Zobrazeno 1 - 10
of 988
pro vyhledávání: '"Paul A, Foster"'
Autor:
Dan J Stein, Mingguang He, Paul J Foster, Zihan Sun, Zhuoting Zhu, Jonathan Ipser, Sheri-Michelle Koopowitz, Michaela Joan Grimbly, Ruiye Chen
Publikováno v:
BMJ Open Ophthalmology, Vol 9, Iss 1 (2024)
Background/Aims The emerging concept of retinal age, a biomarker derived from retinal images, holds promise in estimating biological age. The retinal age gap (RAG) represents the difference between retinal age and chronological age, which serves as a
Externí odkaz:
https://doaj.org/article/efbb62ebb0384abebf15083579972095
Autor:
Brian G. Oliver, Paul S. Foster
Publikováno v:
ERJ Open Research, Vol 10, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/16138c711e7d4f90891024a562995069
Autor:
Jemma R Mayall, Jay C Horvat, Niamh E Mangan, Anne Chevalier, Huw McCarthy, Daniel Hampsey, Chantal Donovan, Alexandra C Brown, Antony Y Matthews, Nicole A de Weerd, Eveline D de Geus, Malcolm R Starkey, Richard Y Kim, Katie Daly, Bridie J Goggins, Simon Keely, Steven Maltby, Rennay Baldwin, Paul S Foster, Michael J Boyle, Pradeep S Tanwar, Nicholas D Huntington, Paul J Hertzog, Philip M Hansbro
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 2, Pp 267-293 (2024)
Abstract The uterus is a unique mucosal site where immune responses are balanced to be permissive of a fetus, yet protective against infections. Regulation of natural killer (NK) cell responses in the uterus during infection is critical, yet no studi
Externí odkaz:
https://doaj.org/article/27c077dad3a5489b8adb434699dbf324
Autor:
Emily Warmington, Gabrielle Smith, Vasileios Chortis, Raimunde Liang, Juliane Lippert, Sonja Steinhauer, Laura-Sophie Landwehr, Constanze Hantel, Katja Kiseljak-Vassiliades, Margaret E Wierman, Barbara Altieri, Paul A Foster, Cristina L Ronchi
Publikováno v:
Endocrine Connections, Vol 13, Iss 1, Pp 1-12 (2023)
Adrenocortical carcinoma (ACC) is an aggressive malignancy with limited treatment options. Polo-like kinase 1 (PLK1) is a promising drug target; PLK1 inhibitors (PLK1i) have been investigated in solid cancers and are more effective in TP53-mutated ca
Externí odkaz:
https://doaj.org/article/e4efec62f5f64d8ab3df24cff09f9c14
Autor:
Axel Petzold, Paul J Foster, Praveen J Patel, Anthony P Khawaja, Bing Zhang, Zihan Sun, Peng T Khaw, Denize Atan, Robert N Luben, Stephen Smith, Kelsey V Stuart, Mahantesh I Biradar, Thomas McGillivray
Publikováno v:
BMJ Open Ophthalmology, Vol 9, Iss Suppl 1 (2024)
Externí odkaz:
https://doaj.org/article/7d16647d79a441e0ae558d1dbd4415fa
Autor:
Gang Liu, Tatt Jhong Haw, Malcolm R. Starkey, Ashleigh M. Philp, Stelios Pavlidis, Christina Nalkurthi, Prema M. Nair, Henry M. Gomez, Irwan Hanish, Alan CY. Hsu, Elinor Hortle, Sophie Pickles, Joselyn Rojas-Quintero, Raul San Jose Estepar, Jacqueline E. Marshall, Richard Y. Kim, Adam M. Collison, Joerg Mattes, Sobia Idrees, Alen Faiz, Nicole G. Hansbro, Ryutaro Fukui, Yusuke Murakami, Hong Sheng Cheng, Nguan Soon Tan, Sanjay H. Chotirmall, Jay C. Horvat, Paul S. Foster, Brian GG. Oliver, Francesca Polverino, Antonio Ieni, Francesco Monaco, Gaetano Caramori, Sukhwinder S. Sohal, Ken R. Bracke, Peter A. Wark, Ian M. Adcock, Kensuke Miyake, Don D. Sin, Philip M. Hansbro
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
Abstract Toll-like receptor 7 (TLR7) is known for eliciting immunity against single-stranded RNA viruses, and is increased in both human and cigarette smoke (CS)-induced, experimental chronic obstructive pulmonary disease (COPD). Here we show that th
Externí odkaz:
https://doaj.org/article/c49c73a4f4614f95ae1cab28b0686048
Autor:
Jason L. N. Girkin, Leon A. Sokulsky, Malcolm R. Starkey, Philip M. Hansbro, Paul S. Foster, Adam M. Collison, Joerg Mattes
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
IntroductionEosinophilic esophagitis (EoE) is associated with allergen-driven inflammation of the esophagus and an upregulated Th2 cytokine signature. Recombinant interleukin (IL)-13 (rIL-13) administration to mice induces some of the hallmark featur
Externí odkaz:
https://doaj.org/article/41fd15d331eb4189b86c5a818ebf3301
Autor:
Gianni Virgili, John G Lawrenson, Paul J Foster, Augusto Azuara-Blanco, Mike Clarke, Anthony J King, Ciaran O'Neill, Anish Jindal, Christopher R Cardwell, Meenakshi Sharma, Mary Guiney, Winnie Nolan
Publikováno v:
BMJ Open, Vol 13, Iss 10 (2023)
Introduction Angle-closure is responsible for half of all glaucoma blindness globally. Patients with suspected glaucoma require assessment of the drainage angle by an experienced clinician. The goal of this study is to evaluate the diagnostic perform
Externí odkaz:
https://doaj.org/article/17ce582b8bda4143b552ca19fb2d6b12
Autor:
Martin McKibbin, Tariq Aslam, Sarah Barman, Jenny Barrett, Paul Bishop, Roxana Carare, Usha Chakravarthy, Michelle Chan, Alexander Day, Parul Desai, Bal Dhillon, Andrew Dick, Cathy Egan, Sarah Ennis, Paul Foster, Marcus Fruttiger, John Gallacher, Jane Gibson, Jeremy Guggenheim, Chris Hammond, Alison Hardcastle, Simon Harding, Ruth Hogg, Pirro Hysi, Anthony Khawaja, Gerassimos Lascaratos, Andrew Lotery, Phil Luthert, Tom Macgillivray, Sarah Mackie, Bernadette Mcguinness, Gareth Mckay, Tony Moore, James Morgan, Eoin O’sullivan, Chris Owen, Praveen Patel, Euan Paterson, Axel Petzold, Alicja Rudnicka, Paul J Foster, Naomi Allen, Peng Tee Khaw, Praveen J Patel, Konstantinos Balaskas, Richard Oram, Robert Luben, Tasanee Braithwaite, Graeme Black, Christopher G Owen, Zihan Sun, David Garway-Heath, Thomas Littlejohns, Simon Sheard, Sharon Chua, Pearse Keane, Denize Atan, Savita Madhusudhan, Alexander Doney
Publikováno v:
BMJ Open, Vol 13, Iss 6 (2023)
Purpose The retina provides biomarkers of neuronal and vascular health that offer promising insights into cognitive ageing, mild cognitive impairment and dementia. This article described the rationale and methodology of eye and vision assessments wit
Externí odkaz:
https://doaj.org/article/7aa3818d8e5e4fc3b026f8c7a9faa59c
Autor:
Xiaofan Jiang, Pirro G Hysi, Anthony P Khawaja, Omar A Mahroo, Zihe Xu, Christopher J Hammond, Paul J Foster, Roshan A Welikala, Sarah A Barman, Peter H Whincup, Alicja R Rudnicka, Christopher G Owen, David P Strachan, UK Biobank Eye and Vision Consortium
Publikováno v:
PLoS Genetics, Vol 19, Iss 2, p e1010583 (2023)
The eye is the window through which light is transmitted and visual sensory signalling originates. It is also a window through which elements of the cardiovascular and nervous systems can be directly inspected, using ophthalmoscopy or retinal imaging
Externí odkaz:
https://doaj.org/article/150ba4a65ad84908a2b6b5575876bebf