Zobrazeno 1 - 10
of 883
pro vyhledávání: '"Paul A, Davies"'
Autor:
Paul A. Davies, Hayley J. Fowler, Roberto Villalobos Herrera, Julia Slingo, David L.A. Flack, Mateusz Taszarek
Publikováno v:
Weather and Climate Extremes, Vol 45, Iss , Pp 100696- (2024)
The motivation of our study is to provide forecasters and users complementary guidance and tools to identify and predict atmospheric conditions that could lead to life-threatening flash floods. Using hourly and sub-hourly rainfall datasets, proximity
Externí odkaz:
https://doaj.org/article/c75b8d58fa134098bedc2aa9aae9a5f1
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 621-627 (2024)
A polysubstituted 3-aminoimidazo[5,1-b]oxazol-6-ium framework has been accessed from a new nitrenoid reagent by a two-step ynamide annulation and imidazolium ring-formation sequence. Metalation with Au(I), Cu(I) and Ir(I) at the C2 position provides
Externí odkaz:
https://doaj.org/article/18ce9b5f1cc740948754d9b7bf161fa3
Autor:
Noell Cho, Georgina Kontou, Joshua L. Smalley, Christopher Bope, Jacob Dengler, Kristopher Montrose, Tarek Z. Deeb, Nicholas J. Brandon, Tadashi Yamamoto, Paul A. Davies, Georgios Giamas, Stephen J. Moss
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109512- (2024)
Summary: LMTK3 is a brain-specific transmembrane serine/threonine protein kinase that acts as a scaffold for protein phosphatase-1 (PP1). Although LMKT3 has been identified as a risk factor for autism and epilepsy, its physiological significance is u
Externí odkaz:
https://doaj.org/article/fe648812ed2245d28cd51d531ae0f3c3
Publikováno v:
ACS Omega, Vol 8, Iss 39, Pp 35988-36000 (2023)
Externí odkaz:
https://doaj.org/article/ed9a7fb3fc624213941f3aaa576fad15
Autor:
Joshua L. Smalley, Noell Cho, Shu Fun Josephine Ng, Catherine Choi, Abigail H. S. Lemons, Saad Chaudry, Christopher E. Bope, Jake S. Dengler, Chuansheng Zhang, Matthew N. Rasband, Paul A. Davies, Stephen J. Moss
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
The subunit composition of GABAA receptors and their interaction with beta spectrin complexes influences their localization between the neuronal axon initial segment or dendrites.
Externí odkaz:
https://doaj.org/article/edfc1bb22db642f7ab73e66911075353
Autor:
Joonas Ojala, Janne Pakarinen, Philippos Papadakis, Juha Sorri, Mikael Sandzelius, Daniel M. Cox, Kalle Auranen, Hussam Badran, Paul J. Davies, Tuomas Grahn, Paul T. Greenlees, Jack Henderson, Andrej Herzáň, Rolf-Dietmar Herzberg, Joshua Hilton, Ulrika Jakobsson, David G. Jenkins, David T. Joss, Rauno Julin, Sakari Juutinen, Tibor Kibédi, Joonas Konki, Gregory J. Lane, Matti Leino, Jarkko Liimatainen, Christopher G. McPeake, Olavi Neuvonen, Robert D. Page, Edward Parr, Jari Partanen, Pauli Peura, Panu Rahkila, John Revill, Panu Ruotsalainen, Jan Sarén, Catherine Scholey, Sanna Stolze, Juha Uusitalo, Andrew Ward, Robert Wadsworth
Publikováno v:
Communications Physics, Vol 5, Iss 1, Pp 1-9 (2022)
The authors study an interesting phenomena of shape coexistence in 186Pb. In an elegant and well-documented experiment, they confirm the coexistence of the three 0+ states in the 186Pb nucleus and reassign the shapes associated with the excited 0+ st
Externí odkaz:
https://doaj.org/article/612ea063e0ac48d5b66b59e3323a5564
Autor:
Catherine Choi, Joshua L. Smalley, Abigail H. S. Lemons, Qiu Ren, Christopher E. Bope, Jake S. Dengler, Paul A. Davies, Stephen J. Moss
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Impaired inhibitory signaling underlies the pathophysiology of many neuropsychiatric and neurodevelopmental disorders including autism spectrum disorders and epilepsy. Neuronal inhibition is regulated by synaptic and extrasynaptic γ-aminobutyric aci
Externí odkaz:
https://doaj.org/article/b30ccc0be6cc46cfb9340dd34a6deb46
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Neuroactive steroids (NASs) have potent anxiolytic, anticonvulsant, sedative, and hypnotic actions, that reflect in part their efficacy as GABAAR positive allosteric modulators (PAM). In addition to this, NAS exert metabotropic effects on GABAergic i
Externí odkaz:
https://doaj.org/article/1110699bf1494006862b88d33b2130ba
Publikováno v:
AIP Advances, Vol 11, Iss 4, Pp 045119-045119-9 (2021)
Sum Frequency Generation (SFG) spectroscopy is widely used for studying the di-chain phospholipid monolayers incorporated in model cell membranes. In this context, it is frequently assumed, without justification, that the chains are identical, so the
Externí odkaz:
https://doaj.org/article/8d08d055a38f474dba52246903e7dbcc
Publikováno v:
Astrobiology. 22:1443-1451
It may be that habitable planets are common but life is rare. If future advances in telescopes increasingly suggest this is so, humankind might feel motivated to seed lifeless planets with resilient terrestrial organisms or synthetic forms designed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbdf5f540c07fbf656f64687892e173
https://doi.org/10.1089/ast.2021.0188
https://doi.org/10.1089/ast.2021.0188