Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Paul A, Blair"'
Autor:
Paul W. Blair, Kenneth Kobba, Stephen Okello, Sultanah Alharthi, Prossy Naluyima, Emily Clemens, Hannah Kibuuka, Danielle V. Clark, Francis Kakooza, Mohammed Lamorde, Yukari C. Manabe, J. Stephen Dumler, Acute Febrile Illness
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 7, Pp 1442-1446 (2024)
At 3 severe infection cohort sites in Uganda, Orientia seropositivity was common. We identified 4 seroconversion cases and 1 PCR-positive case. These results provide serologic and molecular support for Orientia spp. circulating in sub-Saharan Africa,
Externí odkaz:
https://doaj.org/article/03b48287b06e468baaf9c6ad0f9943f4
Autor:
Josh G. Chenoweth, Joost Brandsma, Deborah A. Striegel, Pavol Genzor, Elizabeth Chiyka, Paul W. Blair, Subramaniam Krishnan, Elliot Dogbe, Isaac Boakye, Gary B. Fogel, Ephraim L. Tsalik, Christopher W. Woods, Alex Owusu-Ofori, Chris Oppong, George Oduro, Te Vantha, Andrew G. Letizia, Charmagne G. Beckett, Kevin L. Schully, Danielle V. Clark
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-9 (2024)
Abstract Background Sepsis from infection is a global health priority and clinical trials have failed to deliver effective therapeutic interventions. To address complicating heterogeneity in sepsis pathobiology, and improve outcomes, promising precis
Externí odkaz:
https://doaj.org/article/c20dbc2d922941d3a99c931cb0e51535
Autor:
Josh G. Chenoweth, Carlo Colantuoni, Deborah A. Striegel, Pavol Genzor, Joost Brandsma, Paul W. Blair, Subramaniam Krishnan, Elizabeth Chiyka, Mehran Fazli, Rittal Mehta, Michael Considine, Leslie Cope, Audrey C. Knight, Anissa Elayadi, Anne Fox, Ronna Hertzano, Andrew G. Letizia, Alex Owusu-Ofori, Isaac Boakye, Albert A. Aduboffour, Daniel Ansong, Eno Biney, George Oduro, Kevin L. Schully, Danielle V. Clark
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Our limited understanding of the pathophysiological mechanisms that operate during sepsis is an obstacle to rational treatment and clinical trial design. There is a critical lack of data from low- and middle-income countries where the sepsis
Externí odkaz:
https://doaj.org/article/81d492ccfe114c88a466b6acdd447d0a
Autor:
Abraham J Kandathil, Paul W Blair, Jennifer Lu, Raghavendran Anantharam, Kenneth Kobba, Matthew L Robinson, Sultanah Alharthi, Edgar C Ndawula, J Stephen Dumler, Francis Kakooza, Mohammed Lamorde, David L Thomas, Steven L Salzberg, Yukari C Manabe
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 9, p e0012451 (2024)
Metagenomic next generation metagenomic sequencing (mNGS) has proven to be a useful tool in the diagnosis and identification of novel human pathogens and pathogens not identified on routine clinical microbiologic tests. In this study, we applied mNGS
Externí odkaz:
https://doaj.org/article/ede602405b7a41ab964a1ce3530e2cae
Autor:
Adrian C. Paskey, Kevin L. Schully, Logan J. Voegtly, Catherine E. Arnold, Regina Z. Cer, Kenneth G. Frey, Paul W. Blair, Danielle V. Clark, Hong Ge, Allen L. Richards, Christina M. Farris, Kimberly A. Bishop-Lilly
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Infection with either Rickettsia prowazekii or Orientia tsutsugamushi is common, yet diagnostic capabilities are limited due to the short window for positive identification. Until now, although targeted enrichment had been applied to increase sensiti
Externí odkaz:
https://doaj.org/article/3d595ae3e3004b54a1737aa718e68971
Autor:
Paul W. Blair, Joost Brandsma, Josh Chenoweth, Stephanie A. Richard, Nusrat J. Epsi, Rittal Mehta, Deborah Striegel, Emily G. Clemens, Sultanah Alharthi, David A. Lindholm, Ryan C. Maves, Derek T. Larson, Katrin Mende, Rhonda E. Colombo, Anuradha Ganesan, Tahaniyat Lalani, Christopher J. Colombo, Allison A. Malloy, Andrew L. Snow, Kevin L. Schully, Charlotte Lanteri, Mark P. Simons, John S. Dumler, David Tribble, Timothy Burgess, Simon Pollett, Brian K. Agan, Danielle V. Clark, the EPICC COVID-19 Cohort Study Group
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The associations between clinical phenotypes of coronavirus disease 2019 (COVID-19) and the host inflammatory response during the transition from peak illness to convalescence are not yet well understood. Blood plasma samples were collected
Externí odkaz:
https://doaj.org/article/a458538433624485aee259a41be8758b
Autor:
Paul W. Blair, Kenneth Kobba, Francis Kakooza, Matthew L. Robinson, Emmanuel Candia, Jonathan Mayito, Edgar C. Ndawula, Abraham J. Kandathil, Alphonsus Matovu, Gilbert Aniku, Yukari C. Manabe, Mohammed Lamorde
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Epidemiology of febrile illness in Uganda is shifting due to increased HIV treatment access, emerging viruses, and increased surveillance. We investigated the aetiology and outcomes of acute febrile illness in adults presenting to
Externí odkaz:
https://doaj.org/article/1b9ab5ee24c4452f9b4975042244cbad
Autor:
Trishul Siddharthan, Paul W. Blair, Erjia Cui, Jackson Pearce, Phabiola Herrera, Gigi Liu, Joshua East, Ciprian Crainiceanu, Danielle V. Clark, the CCPSEI Research Team, Katherine Fenstermacher
Publikováno v:
ERJ Open Research, Vol 9, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/8e092309926f4cb3863395a882ee51c2
Autor:
Annukka A. R. Antar, Tong Yu, Zoe O Demko, Chen Hu, Jeffrey A. Tornheim, Paul W. Blair, David L. Thomas, Yukari C. Manabe
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe incidence of long COVID is substantial, even in people with mild to moderate acute COVID-19. The role of early viral kinetics in the subsequent development of long COVID is largely unknown, especially in individuals who were not hospi
Externí odkaz:
https://doaj.org/article/8a7e6f4b44784b459b9b8c121d314306
Autor:
Christopher W Woods, Daniel Ansong, Emily Ko, George Oduro, Nehkonti Adams, Andrew Letizia, Charmagne Beckett, Mark G Salvador, William R Hulsey, James V Lawler, Kevin L Schully, Paul W Blair, Rittal Mehta, Chris Kwaku Oppong, Som Tin, Ephraim L Tsalik, Josh Chenoweth, Michelle Rozo, Deborah A Striegel, Joost Brandsma, Lauren McKean, Rachael E Mahle, Subramaniam Krishnan, Michael Prouty, Anne Fox, Dennis Faix, Chris Duplessis, Michael G Gregory, Te Vantha, Alex Kwame Owusu-Ofori, Danielle V Clark
Publikováno v:
BMJ Open, Vol 13, Iss 2 (2023)
Objectives We evaluated the performance of commonly used sepsis screening tools across prospective sepsis cohorts in the USA, Cambodia and Ghana.Design Prospective cohort studies.Setting and participants From 2014 to 2021, participants with two or mo
Externí odkaz:
https://doaj.org/article/985bdbc4adde4301b1d31e95179451ca