Zobrazeno 1 - 10
of 284
pro vyhledávání: '"Paul Yager"'
Autor:
Alexander J Yan, Alaina M Olson, Kris M Weigel, Angelique K Luabeya, Erin Heiniger, Mark Hatherill, Gerard A Cangelosi, Paul Yager
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0308235 (2024)
Tongue swabs hold promise as a non-invasive sample for diagnosing tuberculosis (TB). However, their utility as replacements for sputum has been limited by their varied diagnostic performance in PCR assays compared to sputum. The use of silica-based D
Externí odkaz:
https://doaj.org/article/c9f1fbd884e84e7ab2869fcc1567189d
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The simplest point-of-care assays are usually paper and plastic devices that detect proteins or nucleic acids at low cost and minimal user steps, albeit with poor limits of detection. Digital assays improve limits of detection and analyte qu
Externí odkaz:
https://doaj.org/article/86e407578da248b6b215f73fe52c0d93
Autor:
Kamal G Shah, Mike Roller, Sujatha Kumar, Steven Bennett, Erin Heiniger, Katriel Looney, Joshua Buser, Joshua D Bishop, Paul Yager
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284424 (2023)
Recent advances in electronics and microfluidics have enabled several research groups to develop fully integrated, sample-to-result isothermal nucleic acid amplification test (NAAT) platforms for the point of care. However, high component counts and
Externí odkaz:
https://doaj.org/article/dc51f5623b6c443bac2431677847bd12
Publikováno v:
Cureus.
Autor:
Gonzalo J. Domingo, Paul Yager, Christiane Dolecek, Jeremy Farrar, Buddha Basnyat, Stephen G. Baker, Sabina Dongol, Amit Arjyal, Jennifer L. Osborn, Katherine G. McKenzie, Mitra Singhal, Sujatha Ramachandran, Barry Lutz
Publikováno v:
Diagnostics, Vol 3, Iss 2, Pp 244-260 (2013)
This paper describes a rapid, high-throughput flow-through membrane immunoassay (FMIA) platform. A nitrocellulose membrane was spotted in an array format with multiple capture and control reagents for each sample detection area, and assay steps were
Externí odkaz:
https://doaj.org/article/3e9369d81c01428eb4fe106024f7af14
Autor:
Enos Kline, Barry R. Lutz, Josh Bishop, Lisa Lafleur, Joshua R. Buser, Ryan Gallagher, Paul Yager, Kamal Shah, Sujatha Kumar
Publikováno v:
The Analyst. 145:6875-6886
Nucleic acid amplification test (NAAT)-based point-of-care (POC) devices are rapidly growing for use in low-resource settings. However, key challenges are the ability to store the enzyme-based reagents in dry form in the device and the long-term stab
Autor:
Ratmir Derda, Jesse Gitaka, Catherine M Klapperich, Charles R Mace, Ashok A Kumar, Marya Lieberman, Jacqueline C Linnes, Joerg Jores, Johnson Nasimolo, Joseph Ndung'u, Evans Taracha, Abigail Weaver, Douglas B Weibel, Thomas M Kariuki, Paul Yager
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 5, p e0003676 (2015)
Externí odkaz:
https://doaj.org/article/92739970d70b48d59f98385a99dfd87a
Autor:
Peter Kauffman, Caitlin E Anderson, Arielle J. Howell, Sujatha Kumar, Joshua D. Bishop, Joshua R. Buser, Paul Yager, Maxwell H. Wheeler, Samantha A. Byrnes
Publikováno v:
Analytical Methods. 11:336-345
Paper-microfluidic devices are becoming more common due to their ability to automate diagnostic assays at low cost. Increasingly, paper-microfluidic devices automate more complex, multi-step assays, with the aim of bringing these assays out of the la
Autor:
Paula D. Ladd, David Baker, Joshua R. Buser, Janet A. Englund, Alexis M. Fleming, Eva-Maria Strauch, Paul Yager, Caitlin E Anderson
Publikováno v:
Lab on a Chip. 19:885-896
Influenza is a viral respiratory tract infection responsible for up to 5 million cases of severe infection and nearly 600,000 deaths worldwide each year. While treatments for influenza exist, diagnostics for the virus at the point of care are limited
Autor:
Sujatha Kumar, Kamal Shah, Vidhi Singh, Paul Yager, Barry R. Lutz, Louise Lyth Hansen, Joshua D. Bishop, Erin K. Heiniger
Publikováno v:
Analytical chemistry. 92(19)
Nucleic acid amplification tests (NAATs) are common in laboratory and clinical settings because of their low time to result and exquisite sensitivity and specificity. Laboratory NAATs include onboard positive controls to reduce false negatives and sp