Near-infrared Photosensitizer Based on a Cycloimide Derivative of Chlorin p6: 13,15-N-(3′-Hydroxypropyl)Cycloimide Chlorin p6¶

Autor: Anna Filyasova, Alexei V. Feofanov, Tatyana Karmakova, Marguerite Egret-Charlier, Victoria S. Lebedeva, Anna Pljutinskaya, Raisa I. Yakubovskaya, Andrei Mironov, Paul Vigny, Alexei Grichine

Publikováno v: Photochemistry and Photobiology. 75:633-643

The 13,15-N-(3'-hydroxypropylcycloimide) chlorin p6 (CIC), which absorbs at 711 nm, possesses considerable photoinduced cell-killing activity. It is 43-, 61- and 110-fold more active than chlorin p6, 3-formyl-3-devinyl chlorin p6 and Photogem, respec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956b836b91d7c83c802d5c613d5779d4
https://doi.org/10.1562/0031-8655(2002)0750633nipboa2.0.co2

Tissue distribution and in vivo photosensitizing activity of 13,15-[N-(3-hydroxypropyl)]cycloimide chlorin p6 and 13,15-(N-methoxy)cycloimide chlorin p6 methyl ester

Autor: Jean-Claude Maurizot, Alexei V. Feofanov, Ramzes Ruziyev, Victoria S. Lebedeva, Tatyana Karmakova, Anna Nazarova, Raisa I. Yakubovskaya, Andrey F. Mironov, Andrei Pankratov, Natalia I. Kazachkina, Paul Vigny

Publikováno v: Journal of Photochemistry and Photobiology B: Biology
Journal of Photochemistry and Photobiology B: Biology, Elsevier, 2006, 82, pp.28-36. ⟨10.1016/j.jphotobiol.2005.08.006⟩

Photosensitizers 13,15-[N-(3-hydroxypropyl)]cycloimide chlorin p6 (HPC) and 13,15-(N-methoxy)cycloimide chlorin p6 methyl ester (MMC) absorb at 711 nm and possess high photoinduced cytotoxicity in vitro. Here we report, that photodynamic therapy with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eaf856b324cc438b93c2b2b20281af5
https://doi.org/10.1016/j.jphotobiol.2005.08.006

Photobiological Properties of 13,15-N-(Carboxymethyl)- and 13,15-N-(2-Carboxyethyl)cycloimide Derivatives of Chlorin p6

Autor: Anna Nazarova, Alexei V. Feofanov, Jean-Claude Maurizot, Paul Vigny, Tatyana Karmakova, Grishin Ai, Victoria S. Lebedeva, Andrey F. Mironov, R. D. Ruziev, Iakubovskaia Ri, A.D. Pliutinskaia

Publikováno v: Russian Journal of Bioorganic Chemistry. 30:374-384

Lipophilic derivatives of chlorin p6, 13,15-N-(carboxymethyl)cycloimide methyl ester (CIC1) and 13,15-N-(2-carboxyethyl)cycloimide methyl ester (CIC2), were shown to absorb light in 710 nm region and to be efficient IR photosensitizers. They exhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9b48f435568cc5ac1f57846bee6e8dd
https://doi.org/10.1023/b:rubi.0000037265.90931.49

Formation of Cyclobutane Thymine Dimers from UVA Photosensitization of Pyridopsoralen Monoadducted DNA

Autor: Lidia Andreu Guillo, Paul Vigny, Annick Spassky, Benedicte Beylot

Publikováno v: Photochemistry and Photobiology. 64:349-355

The present report provides evidence that thymine dimerization can be UVA photosensitized at a tetranucleotide, 5′-TATT-3′, by a 7-methyl-pyrido(3, 4-c)psoralen monoadduct in DNA. The efficiency of the photoprocess depends on the tetranucleotide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9af19b9788a5ae3668292c78562f75
https://doi.org/10.1111/j.1751-1097.1996.tb02470.x

SELECTIVE DNA THYMINE DIMERIZATION DURING UVA IRRADIATION IN THE PRESENCE OF A SATURATED PYRIDOPSORALEN

Autor: LidiaAndreu Guillo, Jocelyne Blais, Annick Spassky, Paul Vigny

Publikováno v: Photochemistry and Photobiology. 61:331-335

— It has been recently shown that UVA (320–400 nm) irradiation of DNA in the presence of pyridopsoralens induces the formation of thymine cyclobutane dimers in addition to monoadducts. In this work, we measured the potency of a saturated pyridops

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb7935a807e8d7fe9c028b9d2e577d9
https://doi.org/10.1111/j.1751-1097.1995.tb08617.x