Zobrazeno 1 - 10
of 284
pro vyhledávání: '"Paul Matsudaira"'
Autor:
Wen Hui Tan, Martin Rücklin, Daria Larionova, Tran Bich Ngoc, Bertie Joan van Heuven, Federica Marone, Paul Matsudaira, Christoph Winkler
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109405- (2024)
Summary: Heterozygous mutations in COL10A1 lead to metaphyseal chondrodysplasia type Schmid (MCDS), a skeletal disorder characterized by epiphyseal abnormalities. Prior analysis revealed impaired trimerization and intracellular retention of mutant co
Externí odkaz:
https://doaj.org/article/60581a735fe147b5b4ec1a0aa1ba6ee9
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract During gastrulation of the zebrafish embryo, the cap of blastoderm cells organizes into the axial body plan of the embryo with left–right symmetry and head–tail, dorsal–ventral polarities. Our labs have been interested in the mechanics
Externí odkaz:
https://doaj.org/article/78d28d1de5274be8a614a4b4705eb4b1
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104280- (2022)
Summary: In the mammalian intestine, stem cells (ISCs) replicate in basal crypts, translocate along the villus, and undergo cell death. This pattern of renewal occurs in the zebrafish intestine in which villi are elongated into villar ridges (VR) sep
Externí odkaz:
https://doaj.org/article/e8454c4df4424567a74ffeb08444b007
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 6, Pp 1879-1891 (2020)
Externí odkaz:
https://doaj.org/article/111281c509ba476c9f85d64952a4a9b8
Autor:
Wen Hui Tan, Bich Ngoc Tran, Daria Larionova, Bertie Joan van Heuven, Federica Marone, Martin Rücklin, Paul Matsudaira, Christoph Winkler
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 101046- (2021)
Externí odkaz:
https://doaj.org/article/04fa312aa1494e04bb67944a4aefc013
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232755 (2020)
The quality control of intracellular proteins is achieved by degrading misfolded proteins which cannot be refolded by molecular chaperones. In eukaryotes, such degradation is handled primarily by the ubiquitin-proteasome system. However, it remained
Externí odkaz:
https://doaj.org/article/4a865fd316094096851c71c262bae1d3
Autor:
Sangjin Ryu, Paul Matsudaira
Publikováno v:
JMST Advances. 3:35-40
The stalk of Vorticella convallaria, a sessile microorganism, is a model for calcium-powered cellular contraction and biomimetic actuators because of its high contraction speed and unique energy source. Usually, the stalk coiling follows the contract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7fc9f70649a0149deb010ef24f9ed02
https://doi.org/10.1007/s42791-021-00041-z
https://doi.org/10.1007/s42791-021-00041-z
Publikováno v:
G3: Genes, Genomes, Genetics, 10 (6)
G3: Genes, Genomes, Genetics, Vol 10, Iss 6, Pp 1879-1891 (2020)
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 10, Iss 6, Pp 1879-1891 (2020)
G3: Genes|Genomes|Genetics
Protein quality control in the cytosol (CytoQC) is an important cellular pathway consisting of a network of components which monitor the folding of cytosolic proteins and ensure the efficient removal of aberrant ones. Our understanding of CytoQC mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0609c2b3c33f8ab216a3d62f4703fbf6
https://doi.org/10.1534/g3.120.401186
https://doi.org/10.1534/g3.120.401186
Autor:
Sangjin Ryu, Paul Matsudaira
Publikováno v:
JMST Advances. 2:9-14
The stalk of Vorticella convallaria, a sessile ciliated protozoan, contracts in a few milliseconds at a maximum speed of ~ 10 mm/s and generates a contractile force of ~ 10 nN. After powerful contraction, the stalk slowly returns to its extended stat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18b5739f5fefe125bbb708ec31e2351e
https://doi.org/10.1007/s42791-019-00028-x
https://doi.org/10.1007/s42791-019-00028-x
Publikováno v:
BioTechniques, Vol 41, Iss 3, Pp 295-298 (2006)
Wet electron microscopy (EM) is a new imaging method with the potential to allow higher spatial resolution of samples. In contrast to most EM methods, it requires little time to perform and does not require complicated equipment or difficult steps. W
Externí odkaz:
https://doaj.org/article/029b2ef65bcb40b398f7b2788ff752ff