Zobrazeno 1 - 10
of 399
pro vyhledávání: '"Paul Cos"'
Publikováno v:
ACS Omega, Vol 9, Iss 32, Pp 34808-34828 (2024)
Externí odkaz:
https://doaj.org/article/6cc7d4f7c0814da186471771f9e8114f
Autor:
Clara M. Bento, Kevin van Calster, Tatiana Piller, Gabriel S. Oliveira, Linda de Vooght, Davie Cappoen, Paul Cos, M. Salomé Gomes, Tânia Silva
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT Mycobacterium abscessus (Mab) is an emerging pathogen that poses a severe health threat, especially in people with cystic fibrosis and other chronic lung diseases. Available drugs are largely ineffective due to an exquisite intrinsic resista
Externí odkaz:
https://doaj.org/article/560d5dfe8a07432fafc1a54d9968bc84
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Dry eye disease (DED) is a challenge in ophthalmology. Rat models represent valuable tools to study the pathophysiology and to develop novel treatments. A major challenge in DED research is detecting multiple biomarkers in a low tear volume
Externí odkaz:
https://doaj.org/article/cf92bd06e82d4f20a17c0e1a3fad8ad6
Autor:
Natalia Smiejkowska, Lauren Oorts, Kevin Van Calster, Linda De Vooght, Rob Geens, Henri-Philippe Mattelaer, Koen Augustyns, Sergei V. Strelkov, Dirk Lamprecht, Koen Temmerman, Yann G.-J. Sterckx, Davie Cappoen, Paul Cos
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
ABSTRACTThe World Health Organization’s goal to combat tuberculosis (TB) is hindered by the emergence of anti-microbial resistance, therefore necessitating the exploration of new drug targets. Multidrug regimens are indispensable in TB therapy as t
Externí odkaz:
https://doaj.org/article/c8fac40f6384460fafe887ecb260e268
Autor:
Yamila Lebeque Pérez, Gabriel Llauradó Maury, Manuel de Jesús Serrat Díaz, Paul Cos, Guillermo Antonio Barreto Argilagos
Publikováno v:
Revista Información Científica, Vol 103, Iss 0, Pp e4364-e4364 (2024)
Introducción: los bioderivados propuestos como candidatos a ingredientes alimentarios suelen requerir ciertas evaluaciones para las aplicaciones inmunonutricionales Los hongos comestibles-medicinales son un surtidor de compuestos con estas potencial
Externí odkaz:
https://doaj.org/article/e620414e9d2e42159ae3c12e7cb6908a
Autor:
Aiva Plotniece, Arkadij Sobolev, Claudiu T. Supuran, Fabrizio Carta, Fredrik Björkling, Henrik Franzyk, Jari Yli-Kauhaluoma, Koen Augustyns, Paul Cos, Linda De Vooght, Matthias Govaerts, Juliana Aizawa, Päivi Tammela, Raivis Žalubovskis
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Natural products and analogues are a source of antibacterial drug discovery. Considering drug resistance levels emerging for antibiotics, identification of bacterial metalloenzymes and the synthesis of selective inhibitors are interesting for antibac
Externí odkaz:
https://doaj.org/article/d7d196adf4464caaa61e8aa20fcbc597
Autor:
Laurence Van Moll, Milan Wouters, Jeroen De Smet, Linda De Vooght, Peter Delputte, Mik Van Der Borght, Paul Cos
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT As effector molecules of the innate immune system, antimicrobial peptides (AMPs) have gathered substantial interest as a potential future generation of antibiotics. Here, we demonstrate the anti-Pseudomonas activity and lipopolysaccharide (L
Externí odkaz:
https://doaj.org/article/7ec5e122c8ad4462addf907e5e73124a
Publikováno v:
Vaccines, Vol 12, Iss 1, p 97 (2024)
Respiratory Syncytial Virus (RSV) poses a significant global health concern as a major cause of lower respiratory tract infections (LRTIs). Over the last few years, substantial efforts have been directed towards developing vaccines and therapeutics t
Externí odkaz:
https://doaj.org/article/8c40d94952fd47528738cb91a9a4ba99
Autor:
Jesus Augusto Vazquez-Rodriguez, Bahaa Shaqour, Clara Guarch-Pérez, Emilia Choińska, Martijn Riool, Bart Verleije, Koen Beyers, Vivian J. A. Costantini, Wojciech Święszkowski, Sebastian A. J. Zaat, Paul Cos, Antonio Felici, Livia Ferrari
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Biomaterial-associated infections are a major healthcare challenge as they are responsible for high disease burden in critically ill patients. In this study, we have developed drug-eluting antibacterial catheters to prevent catheter-related
Externí odkaz:
https://doaj.org/article/063a964a93684d7aa1e518dfdf52a798
Autor:
Kim Stobbelaar, Thomas C. Mangodt, Winke Van der Gucht, Lise Delhaise, Jasmine Andries, Valérie Gille, Cyril Barbezange, Annemieke Smet, Benedicte Y. De Winter, Jozef J. De Dooy, Tom Schepens, Els L. I. M. Duval, Paul Cos, Philippe G. Jorens, Stijn Verhulst, Peter L. Delputte
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT The respiratory syncytial virus (RSV) represents the leading cause of viral lower respiratory tract infections (LRTI) in children worldwide and is associated with significant morbidity and mortality rates. The clinical picture of an RSV infe
Externí odkaz:
https://doaj.org/article/55eb0953477e4672831e926ac266fd1b