Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Paul S. Freemont"'
Publikováno v:
Extracellular Vesicle, Vol 4, Iss , Pp 100050- (2024)
Can a combination of the extracellular vesicle (EV) research community’s latest consensus guidance (MISEV2023) along with synthetic biology’s engineering approaches and responsible innovation framework help to accelerate future EV-based industria
Externí odkaz:
https://doaj.org/article/fc4f219ca647476f905930ad486afd40
Autor:
Michael A. Crone, Paul S. Freemont
Publikováno v:
Frontiers in Science, Vol 2 (2024)
Externí odkaz:
https://doaj.org/article/067c66eb68474061949cdf221b8954d0
Autor:
Michael A. Crone, Seran Hakki, Joe Fenn, Jie Zhou, Carolina Rosadas de Oliveira, Kieran J. Madon, Aleksandra Koycheva, Anjna Badhan, Jakob Jonnerby, Sean Nevin, Emily Conibear, Romain Derelle, Robert Varro, Constanta Luca, Shazaad Ahmad, Maria Zambon, Wendy S. Barclay, Jake Dunning, Paul S. Freemont, Graham P. Taylor, Ajit Lalvani
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/933e21f2da6a44f190888eb0cb8b139a
Publikováno v:
npj Systems Biology and Applications, Vol 8, Iss 1, Pp 1-7 (2022)
Abstract Synthetic networks require complex intertwined genetic regulation often relying on transcriptional activation or repression of target genes. CRISPRi-based transcription factors facilitate the programmable modulation of endogenous or syntheti
Externí odkaz:
https://doaj.org/article/910724e32624468682f45dfa01157ca8
Autor:
Richard J. R. Kelwick, Alexander J. Webb, Amelie Heliot, Clara Tresserras Segura, Paul S. Freemont
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 5, Pp n/a-n/a (2023)
Abstract Extracellular vesicles (EVs) are lipid‐membrane nanoparticles that are shed or secreted by many different cell types. The EV research community has rapidly expanded in recent years and is leading efforts to deepen our understanding of EV b
Externí odkaz:
https://doaj.org/article/2f142b92ffd347f7b88edb00369da744
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-5 (2022)
A Global Forum on Synthetic Biology is needed to engage policymakers with practitioners across borders at the highest level. The international community needs a global confidence-building measure focused on discussing policy futures for the age of en
Externí odkaz:
https://doaj.org/article/23ebfd96f5814f06a973574d191dfc7e
Publikováno v:
Engineering Biology, Vol 6, Iss 2-3, Pp 62-68 (2022)
Abstract In synthetic biology, biosensors are routinely coupled with a gene expression system for detecting small molecules and physical signals. We reveal a fluorescent complex, based on the interaction of an Escherichia coli double bond reductase (
Externí odkaz:
https://doaj.org/article/ca0717437d9b49178306015f883d97e3
Autor:
Garrett Wong, Li Rong Lim, Yong Quan Tan, Maybelle Kho Go, David J. Bell, Paul S. Freemont, Wen Shan Yew
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
The ergot alkaloids are a class of natural products known for their pharmacologically privileged molecular structure that are used in the treatment of neurological ailments. Here the authors report on the production of the ergot (fungus)-derived ther
Externí odkaz:
https://doaj.org/article/9f9cc56627a54e64802913fd8933f053
Autor:
Claudia E. Vickers, Paul S. Freemont
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-4 (2022)
Synthetic biology has played a key role in responding to the current pandemic. Biofoundries are critical synthetic biology infrastructure which should be available to all nations as a part of their independent bioengineering, biosecurity, and counter
Externí odkaz:
https://doaj.org/article/6f69d81c51e840d8a14cbbb0c7be5802
Autor:
Ping Han, Maybelle K. Go, Jeng Yeong Chow, Bo Xue, Yan Ping Lim, Michael A. Crone, Marko Storch, Paul S. Freemont, Wen Shan Yew
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract An overreliance on commercial, kit-based RNA extraction in the molecular diagnoses of infectious disease presents a challenge in the event of supply chain disruptions and can potentially hinder testing capacity in times of need. In this stud
Externí odkaz:
https://doaj.org/article/adbe31d6d62648fcadffb1dafb644a27