Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Paul, Zakrevsky"'
Autor:
Paul Zakrevsky, Bruce A. Shapiro
Publikováno v:
RNA Nanotechnology and Therapeutics ISBN: 9781003001560
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::381f550006bbe779025ec0ec9e37f522
https://doi.org/10.1201/9781003001560-19
https://doi.org/10.1201/9781003001560-19
Autor:
Paul Zakrevsky, Eckart Bindewald, Hadley Humbertson, Mathias Viard, Nomongo Dorjsuren, Bruce A. Shapiro
Publikováno v:
Nanomaterials, Vol 9, Iss 4, p 615 (2019)
Several varieties of small nucleic acid constructs are able to modulate gene expression via one of a number of different pathways and mechanisms. These constructs can be synthesized, assembled and delivered to cells where they are able to impart regu
Externí odkaz:
https://doaj.org/article/8a91c0858f2144309317ac92a4a1f1cf
Autor:
Erin R. Calkins, Gurkeerat Singh, Yi-Ling Kao, Luc Jaeger, Paul Zakrevsky, Stéphanie Baudrey, Vasken L Keleshian
Publikováno v:
Nucleic Acids Research
GNRA tetraloop-binding receptor interactions are key components in the macromolecular assembly of a variety of functional RNAs. In nature, there is an apparent bias for GAAA/11nt receptor and GYRA/helix interactions, with the former interaction being
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec40ae1a24398c7438e03f8577c04ab
http://europepmc.org/articles/PMC7913685
http://europepmc.org/articles/PMC7913685
Autor:
William F. Heinz, Eric A. Fields, Eckart Bindewald, Nomongo Dorjsuren, Luc Jaeger, Bruce A. Shapiro, Htet Khant, Natalia de Val, Paul Zakrevsky, Wojciech Kasprzak, Weimin Wu
Publikováno v:
Nanoscale. 12:2555-2568
Using RNA as a material for nanoparticle construction provides control over particle size and shape at the nano-scale. RNA nano-architectures have shown promise as delivery vehicles for RNA interference (RNAi) substrates, allowing multiple functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5589eb241ac51e655ec27c93958311e0
https://doi.org/10.1039/c9nr08197f
https://doi.org/10.1039/c9nr08197f
Autor:
Bruce A. Shapiro, Kirill A. Afonin, Emily Satterwhite, Mathias Viard, Jaclyn Smollett, Wojciech Kasprzak, Eckart Bindewald, Justin R. Halman, Lorena Parlea, Paul Zakrevsky
Publikováno v:
RNA & disease (Houston, Tex.)
The targeted and conditional activation of pharmaceuticals is an increasingly important feature in modern personalized medicine. Nucleic acid nanoparticles show tremendous potential in this exploit due to their programmability and biocompatibility. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0beba55a5c0eab0393b66ce9cd939ff4
https://pubmed.ncbi.nlm.nih.gov/34307841
https://pubmed.ncbi.nlm.nih.gov/34307841
Autor:
Anu, Puri, Faisal, Ibrahim, André, O'Reilly Beringhs, Camryn, Isemann, Paul, Zakrevsky, Abigail, Whittenburg, Derek, Hargrove, Tapan, Kanai, Rebecca S, Dillard, Natalia, de Val, Michael H, Nantz, Xiuling, Lu, Bruce A, Shapiro
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 44:102572
We previously reported that hydroxylated oxime ether lipids (OELs) efficiently deliver functional Dicer substrate siRNAs (DsiRNAs) in cells. Here, we explored in vivo utility of these OELs, using OEL4 as a prototype and report that surface modificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c6e60fd4818d9385be651b822f84c4
https://doi.org/10.1016/j.nano.2022.102572
https://doi.org/10.1016/j.nano.2022.102572
Autor:
Camryn Isemann, Serena Zampino, Mathias Viard, Sohaib Alvi, Paul Zakrevsky, Anu Puri, Jeff Clogston, Upendra Chitgupi, Bruce A. Shapiro, Arabella Chen, Jonathan F. Lovell
Publikováno v:
Nanomedicine
Translation potential of RNA interference nanotherapeutics remains challenging due to in vivo off-target effects and poor endosomal escape. Here, we developed novel polyplexes for controlled intracellular delivery of dicer substrate siRNA, using a li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764a4df4adeb71df5a5737e9ad1031e1
https://europepmc.org/articles/PMC8117728/
https://europepmc.org/articles/PMC8117728/
Autor:
Eduardo G Aguilar, Cody Geary, Erin R. Calkins, Vasken L Keleshian, Luc Jaeger, Paul Zakrevsky
Publikováno v:
Nucleic Acids Research
Stable RNAs rely on a vast repertoire of long-range interactions to assist in the folding of complex cellular machineries such as the ribosome. The universally conserved L39/H89 interaction is a long-range GNRA-like/receptor interaction localized in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913c54da5829a4f3e53b8b3f18ca5fc4
https://resolver.caltech.edu/CaltechAUTHORS:20190412-104543880
https://resolver.caltech.edu/CaltechAUTHORS:20190412-104543880
Autor:
Mathias Viard, Bruce A. Shapiro, Taejin Kim, Kirill A. Afonin, Eckart Bindewald, Paul Zakrevsky
Publikováno v:
Nano Letters. 16:1726-1735
RNA is an attractive material for the creation of molecular logic gates that release programmed functionalities only in the presence of specific molecular interaction partners. Here we present HyperFold, a multistrand RNA/DNA structure prediction app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5ccedb0afba1095019c09dff8c94fb
https://doi.org/10.1021/acs.nanolett.5b04651
https://doi.org/10.1021/acs.nanolett.5b04651