Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Paul, O'Reilly"'
Autor:
Becky A. S. Bibby, Niluja Thiruthaneeswaran, Lingjian Yang, Ronnie R. Pereira, Elisabet More, Darragh G. McArt, Paul O’Reilly, Robert G. Bristow, Kaye J. Williams, Ananya Choudhury, Catharine M. L. West
Publikováno v:
BMC Urology, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background The presence of hypoxia is a poor prognostic factor in prostate cancer and the hypoxic tumor microenvironment promotes radioresistance. There is potential for drug radiotherapy combinations to improve the therapeutic ratio. We aim
Externí odkaz:
https://doaj.org/article/dc9fc4ab567343f7a4756b4ec9e09d1b
Publikováno v:
Diagnostics, Vol 12, Iss 5, p 1272 (2022)
Integrating artificial intelligence (AI) tools in the tissue diagnostic workflow will benefit the pathologist and, ultimately, the patient. The generation of such AI tools has two parallel and yet interconnected processes, namely the definition of th
Externí odkaz:
https://doaj.org/article/112623c663b04ac28870535f293874d2
Autor:
Girish N Nadkarni, Zahi A Fayad, Benjamin S Glicksberg, David L Reich, Prem Timsina, Arash Kia, Patricia Kovatch, Jessica K De Freitas, Paul O’Reilly, Allan Just, Dennis Charney, Ishan Paranjpe, Ross O'Hagan, Adam J Russak, Anuradha Lala, Riccardo Miotto, Akhil Vaid, Kipp W Johnson, Matteo Danieletto, Eddye Golden, Dara Meyer, Manbir Singh, Sulaiman Somani, Arjun Kapoor, Sayan Manna, Udit Nangia, Suraj K Jaladanki, Laura M Huckins, Patricia Glowe, Robert M Freeman, Matthew A Levin, Jeffrey Jhang, Adolfo Firpo, Joseph Finkelstein, Judith A Aberg, Emilia Bagiella, Carol R Horowitz, Barbara Murphy, Jagat Narula, Eric J Nestler, V Fuster, Carlos Cordon-Cardo, Erwin P Bottinger, Alexander W Charney
Publikováno v:
BMJ Open, Vol 10, Iss 11 (2020)
Objective The COVID-19 pandemic is a global public health crisis, with over 33 million cases and 999 000 deaths worldwide. Data are needed regarding the clinical course of hospitalised patients, particularly in the USA. We aimed to compare clinical c
Externí odkaz:
https://doaj.org/article/49d3bda439074873861d39f10d7bca65
Autor:
Li Li, Benjamin S Glicksberg, Zichen Wang, Amanda Zheutlin, Yu-Han Kao, Kristin Ayers, Susan Gross, Patricia Kovatch, Sharon Nirenberg, Alexander Charney, Girish Nadkarni, Jessica K De Freitas, Paul O’Reilly, Allan Just, Carol Horowitz, Glenn Martin, Andrea Branch, Dennis Charney, David Reich, William K Oh, Eric Schadt, Rong Chen
Publikováno v:
BMJ Open, Vol 10, Iss 10 (2020)
Objective To assess association of clinical features on COVID-19 patient outcomes.Design Retrospective observational study using electronic medical record data.Setting Five member hospitals from the Mount Sinai Health System in New York City (NYC).Pa
Externí odkaz:
https://doaj.org/article/9f2b15d1af1140eea2d99a82f5bd4707
Autor:
Suzanne C. Carter, Alessandro N. Franciosi, Kate M. O’Shea, Orla M. O’Carroll, Ashutosh Sharma, Aoife Bell, Brian Keogan, Paul O’Reilly, Suzie Coughlan, Sheonagh M. Law, Robert D. Gray, Katherine B. Hisert, Pradeep K. Singh, Gordon Cooke, Brenda Grogan, Cillian F. De Gascun, Charles G. Gallagher, Trevor T. Nicholson, Bradley S. Quon, Edward F. McKone
Publikováno v:
Annals of the American Thoracic Society. 19:1818-1826
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b54326d50a2782a8c4e03f0a9a01c15
https://doi.org/10.1513/annalsats.202111-1266oc
https://doi.org/10.1513/annalsats.202111-1266oc
Autor:
Ahmed Serag, Adrian Ion-Margineanu, Hammad Qureshi, Ryan McMillan, Marie-Judith Saint Martin, Jim Diamond, Paul O'Reilly, Peter Hamilton
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
There has been an exponential growth in the application of AI in health and in pathology. This is resulting in the innovation of deep learning technologies that are specifically aimed at cellular imaging and practical applications that could transfor
Externí odkaz:
https://doaj.org/article/e7e97a5dba9d463789ee06203c1b9f91
Autor:
PJ Michael Deans, Carina Seah, Jessica Johnson, Judit Garcia Gonzalez, Kayla Townsley, Evan Cao, Nadine Schrode, Eli Stahl, Paul O’Reilly, Laura M. Huckins, Kristen J. Brennand
Publikováno v:
medRxiv
Genetic studies of schizophrenia (SCZ) reveal a complex polygenic risk architecture comprised of hundreds of risk variants, the majority of which are common in the population at-large and confer only modest increases in disorder risk. Precisely how g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3041b80568541df9600aaf3475e813
https://doi.org/10.1101/2023.03.20.23287497
https://doi.org/10.1101/2023.03.20.23287497
Autor:
Adam Socrates, Niamh Mullins, Ruben Gur, Raquel Gur, Eli Stahl, Paul O’Reilly, Abraham Reichenberg, Hannah Jones, Stan Zammit, Eva Velthorst
Social-isolation has been linked to a range of psychiatric issues, but the behavioral component that drives it is not well understood. Here, a GWAS is carried out to identify genetic variants which contribute to Social-isolation behaviors in up to 44
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcfc2464977889b1100b5d57100430af
https://doi.org/10.21203/rs.3.rs-2583059/v1
https://doi.org/10.21203/rs.3.rs-2583059/v1
The use of siblings to infer the factors influencing complex traits has been a cornerstone of quantitative genetics. Here we utilise siblings for a novel application: the identification of genetic architecture, specifically that in individuals with e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f6b3d7bb571f420dc6b4c60851b3aa7
https://doi.org/10.1101/2023.02.19.529159
https://doi.org/10.1101/2023.02.19.529159
Autor:
Clive Hoggart, Shing Wan Choi, Judit García-González, Tade Souaiaia, Michael Preuss, Paul O’Reilly
Publikováno v:
bioRxiv
Polygenic Risk Scores (PRS) have huge potential to contribute to biomedical research and to a future of precision medicine, but to date their calculation relies largely on Europeanancestry GWAS data. This global bias makes most PRS substantially less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2435a6006d818f7ac0770df69460d6b3
https://doi.org/10.1101/2023.02.17.528938
https://doi.org/10.1101/2023.02.17.528938