Zobrazeno 1 - 10 of 62 pro vyhledávání: '"Paul, Le Tissier"'
1
Akademický článek
Sex differences in pituitary corticotroph excitability
Autor: Peter J. Duncan, Nicola Romanò, Sooraj V. Nair, Joanne F. Murray, Paul Le Tissier, Michael J. Shipston
Publikováno v: Frontiers in Physiology, Vol 14 (2023)
Stress-related illness represents a major burden on health and society. Sex differences in stress-related disorders are well documented, with women having twice the lifetime rate of depression compared to men and most anxiety disorders. Anterior pitu
Externí odkaz: https://doaj.org/article/c16b4a29507c4546b0c9388d309586eb
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2
Akademický článek
An expression and function analysis of the CXCR4/SDF-1 signalling axis during pituitary gland development.
Autor: Jose Mario Gonzalez-Meljem, Sarah Ivins, Cynthia Lilian Andoniadou, Paul Le Tissier, Peter Scambler, Juan Pedro Martinez-Barbera
Publikováno v: PLoS ONE, Vol 18, Iss 2, p e0280001 (2023)
The chemokine SDF-1 (CXCL12) and its receptor CXCR4 control several processes during embryonic development such as the regulation of stem cell proliferation, differentiation, and migration. However, the role of this pathway in the formation of the pi
Externí odkaz: https://doaj.org/article/60e7db68dcd349edb05899958a92d033
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3
Akademický článek
NOTCH activity differentially affects alternative cell fate acquisition and maintenance
Autor: Leonard Cheung, Paul Le Tissier, Sam GJ Goldsmith, Mathias Treier, Robin Lovell-Badge, Karine Rizzoti
Publikováno v: eLife, Vol 7 (2018)
The pituitary is an essential endocrine gland regulating multiple processes. Regeneration of endocrine cells is of therapeutic interest and recent studies are promising, but mechanisms of endocrine cell fate acquisition need to be better characterise
Externí odkaz: https://doaj.org/article/c8ca1d8da38143ab834fb6f0cffe8a73
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4
Chronic stress facilitates bursting electrical activity in pituitary corticotrophs
Autor: Mehran Fazli, Nicola Romanò, Peter J. Duncan, Michael J Shipston, Richard Bertram, Paul Le Tissier
Publikováno v: The Journal of Physiology. 600:313-332
KEY POINTS Chronic stress (CS) is predicted to modify the electrical excitability of anterior pituitary corticotrophs. Electrophysiological recordings from isolated corticotrophs from CS male mice display spontaneous electrical bursting behaviour com
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ef8d3000b71de109994697b29b69da
https://doi.org/10.1113/jp282367
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5
Hyperprolactinemia in a male pituitary androgen receptor knockout mouse is associated with female‐like lactotroph development
Autor: Lee B. Smith, Helen C. Christian, Paul Le Tissier, Laura O’Hara
Publikováno v: Andrology. 9:1652-1661
Background Circulating prolactin concentration in rodents and humans is sexually dimorphic. Estrogens are a well-characterised stimulator of prolactin release. Circulating prolactin fluctuates throughout the menstrual/estrous cycle of females in resp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::976b4e77618093c8ee2136b2a03973a2
https://doi.org/10.1111/andr.13040
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7
A New Perspective on Regulation of Pituitary Plasticity: The Network of SOX2-Positive Cells May Coordinate Responses to Challenge
Autor: Paul Le Tissier, Patrice Mollard, Joanne Murray
Publikováno v: Endocrinology
Endocrinology, 2022, 163 (8), pp.bqac089. ⟨10.1210/endocr/bqac089⟩
Plasticity of function is required for each of the anterior pituitary endocrine axes to support alterations in the demand for hormone with physiological status and in response to environmental challenge. This plasticity is mediated at the pituitary l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4f7d63756901a9983eec3e0dd2f445
https://doi.org/10.1210/endocr/bqac089
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8
Corticotroph isolation from Pomc-eGFP mice reveals sustained transcriptional dysregulation characterising a mouse model of glucocorticoid-induced suppression of the hypothalamus-pituitary-adrenal axis
Autor: Peter J, Duncan, Heather, McClafferty, Oscar, Nolan, Qinghui, Ding, Natalie Z M, Homer, Paul, Le Tissier, Brian R, Walker, Michael J, Shipston, Nicola, Romanò, Thomas J G, Chambers
Publikováno v: Journal of neuroendocrinology. 34(7)
Glucocorticoids (GC) are prescribed for periods 3 months to 1%-3% of the UK population; 10%-50% of these patients develop hypothalamus-pituitary-adrenal (HPA) axis suppression, which may last over 6 months and is associated with morbidity and mortali
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ae451722354538eb2fd8be8361be4322
https://pubmed.ncbi.nlm.nih.gov/35833423
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10
Renewing an old interest: Pituitary folliculostellate cells
Autor: Patrice Mollard, Paul Le Tissier
Publikováno v: Journal of Neuroendocrinology
Journal of Neuroendocrinology, Wiley, 2021, pp.e13053. ⟨10.1111/jne.13053⟩
Journal of Neuroendocrinology, 2021, 33 (11), pp.e13053. ⟨10.1111/jne.13053⟩
International audience; Anterior pituitary folliculostellate (FS) cells, first described almost 50 years ago, have a wide range of functions with respect to supporting and coordinating endocrine cell function, in particular through paracrine and gap
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5c55c3cce51984cc8a322b1c099537
https://hal.archives-ouvertes.fr/hal-03428405
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