Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Paul, Lasko"'
Autor:
Amel Chaouch, Paul Lasko
Publikováno v:
Fly, Vol 15, Iss 1, Pp 28-37 (2021)
Drosophila melanogaster has proven to be a powerful genetic model to study human disease. Approximately 75% of human disease-associated genes have homologs in the fruit fly and regulatory pathways are highly conserved in Drosophila compared to humans
Externí odkaz:
https://doaj.org/article/ef971620f3404265bc9c7fa9c9f0808f
Publikováno v:
PLoS Biology, Vol 19, Iss 1, p e3001060 (2021)
Collective migration of cohesive tissues is a fundamental process in morphogenesis and is particularly well illustrated during gastrulation by the rapid and massive internalization of the mesoderm, which contrasts with the much more modest movements
Externí odkaz:
https://doaj.org/article/5863d074219b4e678360d007ddb222bd
Autor:
Charles C Y Xu, Claire Ramsay, Mitra Cowan, Mehrnoush Dehghani, Paul Lasko, Rowan D H Barrett
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0249439 (2021)
We demonstrate that simple, non-invasive environmental DNA (eDNA) methods can detect transgenes of genetically modified (GM) animals from terrestrial and aquatic sources in invertebrate and vertebrate systems. We detected transgenic fragments between
Externí odkaz:
https://doaj.org/article/f412641795c4418d91b2e1b2333a0934
Autor:
Annabelle Dold, Hong Han, Niankun Liu, Andrea Hildebrandt, Mirko Brüggemann, Cornelia Rücklé, Heike Hänel, Anke Busch, Petra Beli, Kathi Zarnack, Julian König, Jean-Yves Roignant, Paul Lasko
Publikováno v:
PLoS Genetics, Vol 16, Iss 1, p e1008581 (2020)
Makorins are evolutionary conserved proteins that contain C3H-type zinc finger modules and a RING E3 ubiquitin ligase domain. In Drosophila, maternal Makorin 1 (Mkrn1) has been linked to embryonic patterning but the mechanism remained unsolved. Here,
Externí odkaz:
https://doaj.org/article/f269777d24fd405bb6f2a90e862f6c95
Autor:
Gareth Baynam, Stephanie Broley, Alicia Bauskis, Nicholas Pachter, Fiona McKenzie, Sharron Townshend, Jennie Slee, Cathy Kiraly-Borri, Anand Vasudevan, Anne Hawkins, Lyn Schofield, Petra Helmholz, Richard Palmer, Stefanie Kung, Caroline E. Walker, Caron Molster, Barry Lewis, Kym Mina, John Beilby, Gargi Pathak, Cathryn Poulton, Tudor Groza, Andreas Zankl, Tony Roscioli, Marcel E. Dinger, John S. Mattick, William Gahl, Stephen Groft, Cynthia Tifft, Domenica Taruscio, Paul Lasko, Kenjiro Kosaki, Helene Wilhelm, Bela Melegh, Jonathan Carapetis, Sayanta Jana, Gervase Chaney, Allison Johns, Peter Wynn Owen, Frank Daly, Tarun Weeramanthri, Hugh Dawkins, Jack Goldblatt
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-8 (2017)
Abstract Background New approaches are required to address the needs of complex undiagnosed diseases patients. These approaches include clinical genomic diagnostic pipelines, utilizing intra- and multi-disciplinary platforms, as well as specialty-spe
Externí odkaz:
https://doaj.org/article/fd1d44fbca064efaae5bfc0d962bda6b
Publikováno v:
Fly, Vol 11, Iss 1, Pp 65-74 (2017)
Synthesis of polypeptides from mRNA (translation) is a fundamental cellular process that is coordinated and catalyzed by a set of canonical ‘translation factors’. Surprisingly, the translation factors of Drosophila melanogaster have not yet been
Externí odkaz:
https://doaj.org/article/385c1b6a366945f4913f62c741005a6e
Publikováno v:
Biology Open, Vol 5, Iss 8, Pp 1040-1051 (2016)
The centrosome-associated proteins Ninein (Nin) and Ninein-like protein (Nlp) play significant roles in microtubule stability, nucleation and anchoring at the centrosome in mammalian cells. Here, we investigate Blastoderm specific gene 25D (Bsg25D),
Externí odkaz:
https://doaj.org/article/80aee09a94bb4d2ea174109c883d66c9
Autor:
Marjon van Slegtenhorst, Paul Lasko, Jill R. Murrell, Romy van de Putte, Courtney Manning, Mary-Alice Abbott, Constance T. R. M. Stumpel, Jacqueline Leonard, Iris A.L.M. van Rooij, Servi J. C. Stevens, Han G. Brunner, Alexander Hoischen, Karin E. M. Diderich, Louise C. Pyle, Jorune Balciuniene
Publikováno v:
Clinical Genetics, 101, 183-189
Clinical Genetics, 101, 2, pp. 183-189
Clinical Genetics, 101(2), 183-189. Wiley
Clinical Genetics, 101(2), 183-189. Wiley-Blackwell Publishing Ltd
Clinical Genetics, 101, 2, pp. 183-189
Clinical Genetics, 101(2), 183-189. Wiley
Clinical Genetics, 101(2), 183-189. Wiley-Blackwell Publishing Ltd
Contains fulltext : 248942.pdf (Publisher’s version ) (Open Access) The caudal type homeobox 2 (CDX2) gene encodes a developmental regulator involved in caudal body patterning. Only three pathogenic variants in human CDX2 have been described, in pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377efc2da984ac09bf73ab8baab94197
https://doi.org/10.1111/cge.14076
https://doi.org/10.1111/cge.14076
A fundamental aspect of morphogenesis is the capacity of cells to actively exchange neighbours while maintaining the overall cohesion of the tissue. These cell rearrangements require the dynamic remodelling of cadherin cell adhesions. Many studies ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54ce540b1d0cde5eb6e1f0132c20b073
https://doi.org/10.1101/2023.03.27.534409
https://doi.org/10.1101/2023.03.27.534409
Autor:
Lisa Shao, Jaclyn M. Fingerhut, Brook L. Falk, Hong Han, Giovanna Maldonado, Yuemeng Qiao, Vincent Lee, Elizabeth Hall, Liang Chen, Gordon Polevoy, Greco Hernández, Paul Lasko, Julie A. Brill
Publikováno v:
Development. 150
Drosophila sperm development is characterized by extensive post-transcriptional regulation whereby thousands of transcripts are preserved for translation during later stages. A key step in translation initiation is the binding of eukaryotic initiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0423fb73bebc2361485a190cd14a1cd
https://doi.org/10.1242/dev.200477
https://doi.org/10.1242/dev.200477