Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Paul, Laissue"'
Autor:
Lorenzo Costa, Luis Bermudez-Guzman, Ikram Benouda, Paul Laissue, Adrien Morel, Karen Marcela Jiménez, Thierry Fournier, Laurence Stouvenel, Céline Méhats, Francisco Miralles, Daniel Vaiman
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109260- (2024)
Summary: Preeclampsia is a major hypertensive pregnancy disorder with a 50% heritability. The first identified gene involved in the disease is STOX1, a transcription factor, whose variant Y153H predisposes to the disease. Two rare mutations were also
Externí odkaz:
https://doaj.org/article/b911a702ca1a4fb291a95d0fd611069d
Autor:
Paula Quintero-Ronderos, Karen Marcela Jiménez, Clara Esteban-Pérez, Diego A. Ojeda, Sandra Bello, Dora Janeth Fonseca, María Alejandra Coronel, Harold Moreno-Ortiz, Diana Carolina Sierra-Díaz, Elkin Lucena, Sandrine Barbaux, Daniel Vaiman, Paul Laissue
Publikováno v:
Molecular Medicine, Vol 25, Iss 1, Pp 1-8 (2019)
Abstract Background Human reproductive disorders consist of frequently occurring dysfunctions including a broad range of phenotypes affecting fertility and women’s health during pregnancy. Several female-related diseases have been associated with h
Externí odkaz:
https://doaj.org/article/3d567c3476ac4642a7a39a362ecdee6a
Autor:
Brian Ramírez, María José Niño-Orrego, Daniel Cárdenas, Kevin Enrique Ariza, Karol Quintero, Nora Constanza Contreras Bravo, Caroll Tamayo-Agudelo, María Alejandra González, Paul Laissue, Dora Janeth Fonseca Mendoza
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-9 (2019)
Abstract Background Copy Number variation (CNVs) in genes related to drug absorption, distribution, metabolism and excretion (ADME) are relevant in the interindividual variability of drug response. Studies of the CNVs in ADME genes in Latin America p
Externí odkaz:
https://doaj.org/article/d7c669b14fe44e548d41c67fe3569bb1
Autor:
Paul Laissue
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-13 (2019)
Abstract Colorectal cancer (CRC) is the third most commonly occurring cancer worldwide and the fourth most frequent cause of death having an oncological origin. It has been found that transcription factors (TF) dysregulation, leading to the significa
Externí odkaz:
https://doaj.org/article/3fea0f710be34451b8e22431beb7c649
Autor:
Aurélien Ducat, Betty Couderc, Anthony Bouter, Louise Biquard, Rajaa Aouache, Bruno Passet, Ludivine Doridot, Marie-Benoîte Cohen, Pascale Ribaux, Clara Apicella, Irène Gaillard, Sophia Palfray, Yulian Chen, Alexandra Vargas, Amélie Julé, Léo Frelin, Julie Cocquet, Camino Ruano San Martin, Sébastien Jacques, Florence Busato, Jorg Tost, Céline Méhats, Paul Laissue, Jean-Luc Vilotte, Francisco Miralles, Daniel Vaiman
Publikováno v:
iScience, Vol 23, Iss 5, Pp - (2020)
Summary: STOX1 is a transcription factor involved in preeclampsia and Alzheimer disease. We show that the knock-down of the gene induces rather mild effect on gene expression in trophoblast cell lines (BeWo). We identified binding sites of STOX1 shar
Externí odkaz:
https://doaj.org/article/b54fcc60ee1d4939917d4e09e86f70c3
Autor:
Carlos Alberto Calderon-Ospina, Jubby Marcela Galvez, Claudia López-Cabra, Natalia Morales, Carlos Martín Restrepo, Jesús Rodríguez, Fabio Ancízar Aristizábal-Gutiérrez, Alberto Velez-van-Meerbeke, Paul Laissue, Dora Janeth Fonseca-Mendoza
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundEpilepsy is a serious health problem worldwide. Despite the introduction of new antiepileptic drugs (AEDs) almost 30% of these patients have drug-resistant forms of the disease (DRE), with a significant increase in morbi-mortality.Objective
Externí odkaz:
https://doaj.org/article/9f3719a2c3e144a8b76d410583e31f63
Autor:
Paula Quintero-Ronderos, Eric Mercier, Jean-Christophe Gris, Clara Esteban-Perez, Harold Moreno-Ortiz, Dora Janeth Fonseca, Elkin Lucena, Daniel Vaiman, Paul Laissue
Publikováno v:
Reproductive Biology and Endocrinology, Vol 15, Iss 1, Pp 1-5 (2017)
Abstract Recurrent pregnancy loss (RPL) is a frequently occurring disease, which is classified as idiopathic in more than 50% of cases. THBD, the endothelial cell receptor for thrombin, has been associated with distinct biological processes and consi
Externí odkaz:
https://doaj.org/article/01c86291d1184925b5ce2c02c633083f
Autor:
Heidi Eliana Mateus, Ana María Pérez, Martha Lucía Mesa, Germán Escobar, Jubby Marcela Gálvez, José Ivo Montaño, Martha Lucía Ospina, Paul Laissue
Publikováno v:
BMC Research Notes, Vol 10, Iss 1, Pp 1-7 (2017)
Abstract Objective Orphan diseases must be considered a public health concern, underlying country-specific challenges for their accurate and opportune diagnosis, classification and management. Orphan disease registries have not yet been created in So
Externí odkaz:
https://doaj.org/article/0128ba6a16e14302872cb751e286b7a3
Publikováno v:
Revista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturales. 46:1031-1033
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0108fa2d1188c27b8bc11000e6112ee7
https://doi.org/10.18257/raccefyn.1824
https://doi.org/10.18257/raccefyn.1824
Autor:
Diana Carolina Sierra-Díaz, Adrien Morel, Dora Janeth Fonseca, Nora Contreras, Mariana Angulo-Aguado, Valentina Balaguera, Kevin Llinás-Caballero, Isabel Munevar, Mariana Borras, Mauricio Lema, Henry Idrobo, Daniela Trujillo, Norma Serrano, Ana Isabel Orduz, Diego Lopera, Jaime Gonzalez, Gustavo Rojas, Paula Londoño, Ray Manneh, Catalina Quintero, Paul Laissue, Rodrigo Cabrera, Carlos M Restrepo, William Mantilla
Publikováno v:
Cancer Research. 82:P3-07
Introduction In Colombia Breast cancer (BC), is the most frequent and has the highest mortality rate among all types of cancer. There are few studies of the genomic profile in unselected affected population by BC in Colombia. Some of these studies ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d22d68f4536cb7efa9582c10568c08d1
https://doi.org/10.1158/1538-7445.sabcs21-p3-07-05
https://doi.org/10.1158/1538-7445.sabcs21-p3-07-05