Zobrazeno 1 - 10
of 497
pro vyhledávání: '"Paul, Kubes"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
GLPMs represent a population of fetal liver derived large peritoneal cavity Gata6+ macrophages, with the capacity to invade the tissues they surround. Here, in experimental colon cancer liver metastasis models, the authors show that GLPMs invade live
Externí odkaz:
https://doaj.org/article/a2fda9edf52d4f25bd04e59f9b9e384c
Autor:
Channakeshava Sokke Umeshappa, Patricia Solé, Jun Yamanouchi, Saswat Mohapatra, Bas G. J. Surewaard, Josep Garnica, Santiswarup Singha, Debajyoti Mondal, Elena Cortés-Vicente, Charlotte D’Mello, Andrew Mason, Paul Kubes, Pau Serra, Yang Yang, Pere Santamaria
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Invariant natural killer T (iNKT) cells are tissue-resident immune cells recognizing lipid antigens. Here the authors find that liver, but not lung nor spleen, iNKT cells alter their transcriptome upon systemic treatment of lipid nanoparticles for th
Externí odkaz:
https://doaj.org/article/85b3165ec41e474c9dabb9f4fe3fa4b0
Autor:
Stav Kozlovski, Ofer Regev, Anita Sapoznikov, Marina Kizner, Hagit Achdout, Ekaterina Petrovich-Kopitman, Jacob Elkahal, Yoseph Addadi, Fernanda Vargas E. Silva Castanheira, Sara W. Feigelson, Paul Kubes, Noam Erez, Natalio Garbi, Ronen Alon
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
αLβ2 (LFA-1) mediated interactions with ICAM-1 and ICAM-2 predominate leukocyte-vascular interactions, but their functions in extravascular cell-cell communications is still debated. The roles of these two ligands in leukocyte trafficking, lymphocy
Externí odkaz:
https://doaj.org/article/42ff2249db14402eaf642c4f20e2336e
Autor:
Joel Zindel, Jonas Mittner, Julia Bayer, Simon L. April-Monn, Andreas Kohler, Ysbrand Nusse, Michel Dosch, Isabel Büchi, Daniel Sanchez-Taltavull, Heather Dawson, Mercedes Gomez de Agüero, Kinji Asahina, Paul Kubes, Andrew J. Macpherson, Deborah Stroka, Daniel Candinas
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Abdominal surgery can often lead to complications including the formation of peritoneal adhesions and the molecular mechanisms underlying this process are still unknown. Here, the authors suggest that bacterial contamination drives adhesion formation
Externí odkaz:
https://doaj.org/article/1b8f340ac5fd494498184c00669b8081
Autor:
Rachel M. Kratofil, Paul Kubes
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 11, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/042cefea27474a63aaec906b3357798c
Publikováno v:
Bio-Protocol, Vol 12, Iss 16 (2022)
Abdominal surgeries are frequently associated with the development of post-surgical adhesions. These are irreversible fibrotic scar bands that appear between abdominal organs and the abdominal wall. Patients suffering from adhesions are at risk of se
Externí odkaz:
https://doaj.org/article/9ecbd5e81eff4d71b389d136c87ba569
Autor:
Kevin Brulois, Anusha Rajaraman, Agata Szade, Sofia Nordling, Ania Bogoslowski, Denis Dermadi, Milladur Rahman, Helena Kiefel, Edward O’Hara, Jasper J. Koning, Hiroto Kawashima, Bin Zhou, Dietmar Vestweber, Kristy Red-Horse, Reina E. Mebius, Ralf H. Adams, Paul Kubes, Junliang Pan, Eugene C. Butcher
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The origin and diversity of blood vascular endothelial cells (BEC) in lymphoid tissues is unclear. Here, the authors profile murine BECs from peripheral lymph nodes by single cell analysis and identify subsets of cells specialised for immune cell rec
Externí odkaz:
https://doaj.org/article/45437c711e144229ae3255403b2c7df7
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Neutrophils mobilize rapidly and travel through the vasculature and microcirculation en masse in response to inflammatory stimuli. Here the authors use a microfluidic device and intravital microscopy to show neutrophils move through tissues in a high
Externí odkaz:
https://doaj.org/article/66e0f2cdb49c492393495e7c37afdc29
Autor:
Masaki Honda, Bas G. J. Surewaard, Mayuki Watanabe, Catherine C. Hedrick, Woo-Yong Lee, Kirsty Brown, Kathy D. McCoy, Paul Kubes
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Lamina propria macrophages are at the frontline of defense against intestinal pathogens. Here the authors reveal that CCR2 and NR4A1-dependent CX3CR1+ macrophages form a dense network around the vessels in the lamina propria, and implicate this anato
Externí odkaz:
https://doaj.org/article/22f602f2ddee458286f9c7576dcb809a
Autor:
Kimberly J. Dunham-Snary, Bas GJ. Surewaard, Jeffrey D. Mewburn, Rachel ET. Bentley, Ashley Y. Martin, Oliver Jones, Ruaa Al-Qazazi, Patricia AD. Lima, Paul Kubes, Stephen L. Archer
Publikováno v:
Redox Biology, Vol 49, Iss , Pp 102225- (2022)
Background: Neutrophils play a role in innate immunity and are critical for clearance of Staphylococcus aureus. Current understanding of neutrophil bactericidal effects is that NADPH oxidase produces reactive oxygen species (ROS), mediating bacterial
Externí odkaz:
https://doaj.org/article/c6180755b5904ae7b1e5168555395369