Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Paul, Kornblith"'
Autor:
John Piwowar, Alan Wells, Anuja Chattopadhyay, Paul Kornblith, Michael J. Gabrin, Lisa D. George, Robert L. Ochs, Dennis R Burholt
Publikováno v:
International Journal of Gynecological Cancer. 14:607-615
The treatment of ovarian cancer principally relies on the use of platinum and taxane chemotherapeutic agents. Short-term clinical results have been encouraging, but long-term responses remain limited. In this report, an in vitro assay system that uti
Autor:
Paul Kornblith, Ronald H. Goldfarb
Publikováno v:
Journal of Neuro-Oncology. 18:v-viii
It is widely appreciated that the pathophysiology of advanced brain cancer is intimately related to the extent of tumor invasiveness. A pre-requisite for comprehensively understanding neuro-oncology is therefore the elucidation of the biochemical and
Publikováno v:
Methods in molecular medicine. 110
We provide a detailed description of the ChemoFx Assay, a phenotype-based cell culture assay for predicting anticancer drug responses in individual cancer patients. The ChemoFx Assay is based on the outgrowth and short-term primary culture of epithel
Autor:
Paul, Kornblith, Alan, Wells, Michael J, Gabrin, John, Piwowar, Lisa D, George, Robert L, Ochs, Dennis, Burholt
Publikováno v:
Anticancer research. 23(4)
The biological efficacy of, and spectrum of action of, agents used in treatment of breast cancer are important issues in therapy planning.Techniques used involve monolayer culture and a quantitative microtiter plate-based chemo-response assay. Precis
Autor:
Robert L, Ochs, Jeffrey, Fensterer, N Paul, Ohori, Alan, Wells, Michael, Gabrin, Lisa D, George, Paul, Kornblith
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 39(1-2)
Isolation and growth of malignant cells from solid tumors have often met with disappointing results. Consequently, we have developed a cell culture methodology based on ex vivo explantation of tumor tissue, with subsequent monolayer cell outgrowth. I
Autor:
Paul, Kornblith, Alan, Wells, Michael J, Gabrin, John, Piwowar, Anuja, Chattopadhyay, Lisa D, George, Robert L, Ochs, Dennis, Burholt
Publikováno v:
Anticancer research. 23(1B)
We describe the in vitro patterns of response of explanted primary and recurrent ovarian cancers to platinum- and taxane-based chemotherapeutics. The chemoresponse assay utilizes cells that grow out from tumor fragments and are then challenged with v
Publikováno v:
In Vitro Cellular and Developmental Biology-Animal.
Autor:
Kenneth A. Giuliano, Richard S. Morrison, William C. Welch, Margaret K. Bradley, Janet L. Gross, Paul Kornblith, Ronald H. Goldfarb, Susanne M. Gollin, Richard B. Kitson
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 31(8)
Human glioma-derived cell cultures and lines have proven to be of significant value in the study of the basic properties that contribute to the highly malignant, invasive and angiogenic phenotype of glioblastoma multiforme tumors. It is frequently di
Publikováno v:
Journal of Clinical Oncology. 23:831-831
831 Background: A preliminary study was conducted of the utility of the ChemoFx assay, an ex vivo chemoresponse assay, in predicting the relative effectiveness of combinations of drugs compared to ...
Autor:
Michael J. Gabrin, Paul Kornblith, Alan Wells, Jeffrey Fensterer, N. Paul Ohori, Lisa D. George, Robert L. Ochs
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 39:63
Isolation and growth of malignant cells from solid tumors have often met with disappointing results. Consequently, we have developed a cell culture methodology based on ex vivo explantation of tumor tissue, with subsequent monolayer cell outgrowth. I