Zobrazeno 1 - 10
of 231
pro vyhledávání: '"Paul, Kleihues"'
Autor:
Paul Kleihues, Otmar D. Wiestler
Publikováno v:
Target Organ Toxicity ISBN: 9780429290299
Target Organ Toxicity
Target Organ Toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19eddbcce8b98787d6f1113b47da57bc
https://doi.org/10.4324/9780429290299-9
https://doi.org/10.4324/9780429290299-9
Autor:
Josef Paul Kleihues
Publikováno v:
Das Museumsufer Frankfurt ISBN: 9783035618969
Das Museumsufer Frankfurt
Das Museumsufer Frankfurt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::146b74c81c5831b2d9ce82b148d6a2bb
https://doi.org/10.1515/9783035618969-010
https://doi.org/10.1515/9783035618969-010
Autor:
Lauri A. Aaltonen, Markus J. Mäkinen, Ji Eun Oh, Koichiro Sumi, Hiroko Ohgaki, Paul Kleihues, Linda M. Forsström, Riitta Herva
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 76:848-853
We previously reported a patient who had developed 2 glioblastomas at the age of 54 and 64 years, respectively. The first glioblastoma in the right frontal lobe was treated with surgery and radiotherapy. Ten years later, the patient developed a secon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98eb753c4a23abf4af8f43b965c3dfae
https://doi.org/10.1093/jnen/nlx066
https://doi.org/10.1093/jnen/nlx066
Publikováno v:
Neuro-Oncology. 20:579-581
Precise classification of nervous system tumors into coherent clinicopathologic entities is the necessary first step for the appropriate management of patients. While this has been traditionally performed by histopathology only, recent accelerations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8729fb4d2dba838b061d5615d1a872c5
https://doi.org/10.1093/neuonc/noy023
https://doi.org/10.1093/neuonc/noy023
Autor:
Naosuke Nonoguchi, Takashi Ohta, Anne Vital, Werner Paulus, Felice Giangaspero, Daniela Pierscianek, Kaishi Satomi, Ulrich Sure, David Capper, Manila Antonelli, Michel Mittelbronn, Hiroko Ohgaki, Paul Kleihues, Ji Eun Oh
Publikováno v:
Brain Pathology. 26:517-522
The majority of glioblastomas develop rapidly with a short clinical history (primary glioblastoma IDH wild-type), whereas secondary glioblastomas progress from diffuse astrocytoma or anaplastic astrocytoma. IDH mutations are the genetic hallmark of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::635ae717b89c0e0644bbf6bb77062a9b
https://doi.org/10.1111/bpa.12328
https://doi.org/10.1111/bpa.12328
The revised fourth edition of the WHO classification of Tumours of the Central Nervous System, published in 2016, comprises several newly recognized tumour entities, and a significant restructuring of the classification, mainly based on genetic profi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b612f99a2dff601fa16e9707eef2d6bd
https://doi.org/10.1093/med/9780199651870.003.0001
https://doi.org/10.1093/med/9780199651870.003.0001
Autor:
Felice Giangaspero, Elisabeth J. Rushing, Charles G. Eberhart, Andreas von Deimling, Peter C. Burger, Johan M. Kros, Gregory N. Fuller, Cynthia Hawkins, Arie Perry, Figen Soylemezoglu, David N. Louis, V. Peter Collins, Dominique Figarella-Branger, Caterina Giannini, Kenneth Aldape, Paul Kleihues, M. Beatriz S. Lopes, Hiroko Ohgaki, David W. Ellison, Ho Keung Ng, Guido Reifenberger, Daniel J. Brat, Otmar D. Wiestler, Andrey Korshunov, Werner Paulus, Torsten Pietsch, Marc K. Rosenblum, Pieter Wesseling
Publikováno v:
Brain Pathology. 24:429-435
Major discoveries in the biology of nervous system tumors have raised the question of how non-histological data such as molecular information can be incorporated into the next World Health Organization (WHO) classification of central nervous system t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df43445e2e07e993bb541a3981324683
https://doi.org/10.1111/bpa.12171
https://doi.org/10.1111/bpa.12171
Publikováno v:
Acta Neuropathologica. 126:931-937
Telomerase reverse transcriptase (TERT) is up-regulated in a variety of human neoplasms. Mutations in the core promoter region of the TERT gene, which increases promoter activity, have been reported in melanomas and a variety of human neoplasms, incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aaee584cd61110fb6e144b14dc618e4
https://doi.org/10.1007/s00401-013-1163-0
https://doi.org/10.1007/s00401-013-1163-0
Autor:
Paul Kleihues, Hiroko Ohgaki
Publikováno v:
Clinical Cancer Research. 19:764-772
Glioblastoma is the most frequent and malignant brain tumor. The vast majority of glioblastomas (∼90%) develop rapidly de novo in elderly patients, without clinical or histologic evidence of a less malignant precursor lesion (primary glioblastomas)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1c5f7af8c157ad78a5fdd05474d6a8
https://doi.org/10.1158/1078-0432.ccr-12-3002
https://doi.org/10.1158/1078-0432.ccr-12-3002