Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Paul, Girvan"'
Autor:
Ewelina Stefaniak, Xiangyu Teng, Radosław Kotuniak, Wojciech Bal, Dawid Płonka, Liming Ying, Paul Girvan
Publikováno v:
Metallomics. 12:470-473
N-Truncated Aβ4–42 displays a high binding affinity with CuII. A mechanistic scheme of the interactions between Aβ4–42 and CuII has been proposed using a fluorescence approach. The timescales of different conversion steps were determined. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60aa107fac8e2151680d77a26ac9de30
https://doi.org/10.1039/c9mt00299e
https://doi.org/10.1039/c9mt00299e
Autor:
Jack J. W. A. van Loon, Markéta Kubánková, Ismael López-Duarte, Emma M. Woodcock, Marina K. Kuimova, Nicholas J. Brooks, Paul Girvan, Julia Eckert
Publikováno v:
Biophysical Journal, 116(10), 1984-1993. Biophysical Society
Woodcock, E M, Girvan, P, Eckert, J, Lopez-Duarte, I, Kubánková, M, van Loon, J J W A, Brooks, N J & Kuimova, M K 2019, ' Measuring intracellular viscosity in conditions of hypergravity ', Biophysical Journal, vol. 116, no. 10, pp. 1984-1993 . https://doi.org/10.1016/j.bpj.2019.03.038
Biophys J
Woodcock, E M, Girvan, P, Eckert, J, Lopez-Duarte, I, Kubánková, M, van Loon, J J W A, Brooks, N J & Kuimova, M K 2019, ' Measuring Intracellular Viscosity in Conditions of Hypergravity ', Biophysical Journal, vol. 116, no. 10, pp. 1984-1993 . https://doi.org/10.1016/j.bpj.2019.03.038
Woodcock, E M, Girvan, P, Eckert, J, Lopez-Duarte, I, Kubánková, M, van Loon, J J W A, Brooks, N J & Kuimova, M K 2019, ' Measuring intracellular viscosity in conditions of hypergravity ', Biophysical Journal, vol. 116, no. 10, pp. 1984-1993 . https://doi.org/10.1016/j.bpj.2019.03.038
Biophys J
Woodcock, E M, Girvan, P, Eckert, J, Lopez-Duarte, I, Kubánková, M, van Loon, J J W A, Brooks, N J & Kuimova, M K 2019, ' Measuring Intracellular Viscosity in Conditions of Hypergravity ', Biophysical Journal, vol. 116, no. 10, pp. 1984-1993 . https://doi.org/10.1016/j.bpj.2019.03.038
Gravity-sensitive cellular responses are regularly observed in both specialized and nonspecialized cells. One potential mechanism for this sensitivity is a changing viscosity of the intracellular organelles. Here, we report a novel, to our knowledge,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f384de2f326ade04f56673579980c0e4
https://doi.org/10.1016/j.bpj.2019.03.038
https://doi.org/10.1016/j.bpj.2019.03.038
Autor:
Xiangyu, Teng, Ewelina, Stefaniak, Paul, Girvan, Radosław, Kotuniak, Dawid, Płonka, Wojciech, Bal, Liming, Ying
Publikováno v:
Metallomics : integrated biometal science. 12(4)
N-Truncated Aβ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b21b526fd574cc733653c121919aa75
https://pubmed.ncbi.nlm.nih.gov/32236192
https://pubmed.ncbi.nlm.nih.gov/32236192
Autor:
Haruki Iino, David Rueda, Artur Kaczmarczyk, Paul Girvan, Amir Abdolahzadeh, Peter J. Unrau, Paul Poudevigne-Durance, George P. Moore, Elena V. Dolgosheina, Tianyi Zhang, Matthew D. Newton
Publikováno v:
Biophysical Journal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1873ed418ffeed090f4d746c7bd28ba
https://doi.org/10.1016/j.bpj.2020.11.1345
https://doi.org/10.1016/j.bpj.2020.11.1345
Publikováno v:
Chembiochem
Mutations and post‐translational modifications of amyloid‐β (Aβ) peptide in its N terminus have been shown to increase fibril formation, yet the molecular mechanism is not clear. Here we investigated the kinetics of the interactions of copper w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dfabe8d549f636cf36f16ec839db763
http://europepmc.org/articles/PMC5096041
http://europepmc.org/articles/PMC5096041
Publikováno v:
Biochemistry. 57(43)
The ability of the amyloid-β peptide to bind to redox active metals and act as a source of radical damage in Alzheimer's disease has been largely accepted as contributing to the disease's pathogenesis. However, a kinetic understanding of the molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4efcfa62c1d7dc8772f9cb5a9b22103a
https://pubmed.ncbi.nlm.nih.gov/30265526
https://pubmed.ncbi.nlm.nih.gov/30265526
Publikováno v:
Angewandte Chemie. 127:1243-1246
The kinetics of the interactions between amyloid-β (Aβ) and metal ions are crucial to understanding the physiological and pathological roles of Aβ in the normal brain and in Alzheimer's disease. Using the quenching of a fluorescent probe by Cu(2+)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ccdb66497f4556526f952c17a1282c
https://doi.org/10.1002/ange.201408810
https://doi.org/10.1002/ange.201408810
Publikováno v:
Biophysical Journal. 116:28a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1148e4c26566ad6f0d84eda3fc51f97
https://doi.org/10.1016/j.bpj.2018.11.194
https://doi.org/10.1016/j.bpj.2018.11.194
Publikováno v:
60th Annual Meeting of the Biophysical Society
552A
552A
Biochemical oscillations are ubiquitous in living systems, occurring in many contexts such as circadian rhythms, DNA synthesis etc. In contrast, in vitro chemical oscillators are limited to only a few examples based largely on oxyhalogen chemistry, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dbe4ce52f7c5e3eb0658b0ddde2cb98
https://doi.org/10.1016/j.bpj.2015.11.2955
https://doi.org/10.1016/j.bpj.2015.11.2955