Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Paul, Dunman"'
Autor:
Charlene Desbonnet, Amelia Tait-Kamradt, Monica Garcia-Solache, Paul Dunman, Jeffrey Coleman, Michel Arthur, Louis B. Rice
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT The intrinsic resistance of Enterococcus faecium to ceftriaxone and cefepime (here referred to as “cephalosporins”) is reliant on the presence of class A penicillin-binding proteins (Pbps) PbpF and PonA. Mutants lacking these Pbps exhibi
Externí odkaz:
https://doaj.org/article/0e21ddea2be3440793cb23110dbae309
Autor:
Lori A, Knackstedt, Lizhen, Wu, Jeffrey, Rothstein, Svetlana, Vidensky, John, Gordon, Mercy, Ramanjulu, Paul, Dunman, Benjamin, Blass, Wayne, Childers, Magid, Abou-Gharbia
Publikováno v:
J Pharmacol Exp Ther
Cocaine use disorder currently lacks Food and Drug Administration–approved treatments. In rodents, the glutamate transporter-1 (GLT-1) is downregulated in the nucleus accumbens after cocaine self-administration, and increasing the expression and fu
Autor:
Louis B. Rice, Charlene Desbonnet, Amelia Tait-Kamradt, Monica Garcia-Solache, John Lonks, Thomas M. Moon, Éverton D. D’AndrÉéa, Rebecca Page, Wolfgang Peti, Paul Dunman
Publikováno v:
mBio
mBio, Vol 9, Iss 2, p e00361-18 (2018)
mBio, Vol 9, Iss 2 (2018)
mBio, Vol 9, Iss 2, p e00361-18 (2018)
mBio, Vol 9, Iss 2 (2018)
Enterococcus faecalis strains resistant to penicillin and ampicillin are rare and have been associated with increases in quantities of low-affinity penicillin-binding protein 4 (PBP4) or with amino acid substitutions in PBP4. We report an E. faecalis
Autor:
Lisa K. McNeil, Robert G. K. Donald, Alexey Gribenko, Roger French, Nathaniel Lambert, Shannon L. Harris, Thomas R. Jones, Sheng Li, Gary Zlotnick, Ulrich Vogel, Heike Claus, Raquel Abad, Julio A. Vazquez, Ray Borrow, Jamie Findlow, Muhamed-Kheir Taha, Ala-Eddine Deghmane, Dominique A. Caugant, Paula Kriz, Martin Musilek, Xin Wang, Jeni Vuong, Leonard W. Mayer, Michael W. Pride, Kathrin U. Jansen, Annaliesa S. Anderson, Paul Dunman
Publikováno v:
mBio
mBio, American Society for Microbiology, 2018, 9 (2), ⟨10.1128/mBio.00036-18⟩
Repisalud
Instituto de Salud Carlos III (ISCIII)
mBio, 2018, 9 (2), ⟨10.1128/mBio.00036-18⟩
mBio, Vol 9, Iss 2, p e00036-18 (2018)
mBio, Vol 9, Iss 2 (2018)
mBio, American Society for Microbiology, 2018, 9 (2), ⟨10.1128/mBio.00036-18⟩
Repisalud
Instituto de Salud Carlos III (ISCIII)
mBio, 2018, 9 (2), ⟨10.1128/mBio.00036-18⟩
mBio, Vol 9, Iss 2, p e00036-18 (2018)
mBio, Vol 9, Iss 2 (2018)
Bivalent rLP2086 (Trumenba), a vaccine for prevention of Neisseria meningitidis serogroup B (NmB) disease, was licensed for use in adolescents and young adults after it was demonstrated that it elicits antibodies that initiate complement-mediated kil
Autor:
Lamia Harper, Divya Balasubramanian, Elizabeth A. Ohneck, William E. Sause, Jessica Chapman, Bryan Mejia-Sosa, Tenzin Lhakhang, Adriana Heguy, Aristotelis Tsirigos, Beatrix Ueberheide, Jeffrey M. Boyd, Desmond S. Lun, Victor J. Torres, Anthony R. Richardson, Paul Dunman
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
mBio
mBio, Vol 9, Iss 1, p e02272-17 (2018)
mBio
mBio, Vol 9, Iss 1, p e02272-17 (2018)
Staphylococcus aureus is a versatile bacterial pathogen that can cause significant disease burden and mortality. Like other pathogens, S. aureus must adapt to its environment to produce virulence factors to survive the immune responses evoked by infe
Publikováno v:
mSphere, Vol 3, Iss 1 (2018)
mSphere
mSphere, Vol 3, Iss 1, p e00500-17 (2018)
mSphere
mSphere, Vol 3, Iss 1, p e00500-17 (2018)
Methicillin-resistant Staphylococcus aureus (MRSA) presents one of the most serious health concerns worldwide. The WHO labeled it as a “high-priority” pathogen in 2017, also citing the more recently emerged vancomycin-intermediate and -resistant
Publikováno v:
mBio, Vol 8, Iss 4, p e00873-17 (2017)
mBio, Vol 8, Iss 4 (2017)
mBio
mBio, Vol 8, Iss 4 (2017)
mBio
The airways of cystic fibrosis (CF) patients have thick mucus, which fosters chronic, polymicrobial infections. Pseudomonas aeruginosa and Staphylococcus aureus are two of the most prevalent respiratory pathogens in CF patients. In this study, we tes
Autor:
Jun-Rong Wei, Daryl L. Richie, Mina Mostafavi, Louis E. Metzger, Christopher M. Rath, William S. Sawyer, Kenneth T. Takeoka, Charles R. Dean, Paul Dunman
Publikováno v:
mSphere, Vol 2, Iss 4 (2017)
mSphere
mSphere, Vol 2, Iss 4, p e00199-17 (2017)
mSphere
mSphere, Vol 2, Iss 4, p e00199-17 (2017)
Acinetobacter baumannii is a Gram-negative pathogen for which new therapies are needed. The lipid A biosynthetic pathway has several potential enzyme targets for the development of anti-Gram-negative agents (e.g., LpxC). However, A. baumannii ATCC 19
Autor:
Travis B. Nielsen, Paul Pantapalangkoor, Jun Yan, Brian M. Luna, Ken Dekitani, Kevin Bruhn, Brandon Tan, Justin Junus, Robert A. Bonomo, Ann Marie Schmidt, Michael Everson, Frederick Duncanson, Terence M. Doherty, Lin Lin, Brad Spellberg, Paul Dunman
Publikováno v:
mBio, Vol 8, Iss 4, p e00818-17 (2017)
mBio, Vol 8, Iss 4 (2017)
mBio
mBio, Vol 8, Iss 4 (2017)
mBio
For more than a century, diabetic patients have been considered immunosuppressed due to defects in phagocytosis and microbial killing. We confirmed that diabetic mice were hypersusceptible to bacteremia caused by Gram-negative bacteria (GNB), dying a
Autor:
Shawn French, Jean-Philippe Côtôé, Jonathan M. Stokes, Ray Truant, Eric D. Brown, Paul Dunman
Publikováno v:
mBio, Vol 8, Iss 2 (2017)
mBio
mBio, Vol 8, Iss 2, p e01977-16 (2017)
mBio
mBio, Vol 8, Iss 2, p e01977-16 (2017)
Perturbation of cellular processes is a prevailing approach to understanding biology. To better understand the complicated biology that defines bacterial shape, a sensitive, high-content platform was developed to detect multiple morphological defect