Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Paul, Bornstein"'
Autor:
Christina J. Newcomb, Yaping Lei, Yan Zhou, Malcolm L. Snead, Samuel I. Stupp, Zhan Huang, Brad A. Amendt, Paul Bornstein
Publikováno v:
Biomaterials. 61:216-228
Tissue regeneration and development involves highly synchronized signals both between cells and with the extracellular environment. Biomaterials can be tuned to mimic specific biological signals and control cell response(s). As a result, these materi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85252f3a8d29dcd8766ded82c730968b
https://doi.org/10.1016/j.biomaterials.2015.05.035
https://doi.org/10.1016/j.biomaterials.2015.05.035
Autor:
John L. Mignone, Veronica Muskheli, Hans Reinecke, Thomas E. Robey, Paul Bornstein, Charles E. Murry
Publikováno v:
Cardiovascular Pathology. 22:91-95
Fibrosis around cardiac cell injections represents an obstacle to graft integration in cell-based cardiac repair. Thrombospondin-2 (TSP-2) is a pro-fibrotic, anti-angiogenic matricellular protein and an attractive target for therapeutic knockdown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547ed83cf28b41c369271452a7d86ed3
https://doi.org/10.1016/j.carpath.2012.03.005
https://doi.org/10.1016/j.carpath.2012.03.005
Publikováno v:
Wound Repair and Regeneration. 19:134-148
Here, we define dynamic reciprocity (DR) as an ongoing, bidirectional interaction among cells and their surrounding microenvironment. In this review, we posit that DR is especially meaningful during wound healing as the DR-driven biochemical, biophys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74fccd9d27edc55431226039d1774583
https://doi.org/10.1111/j.1524-475x.2011.00673.x
https://doi.org/10.1111/j.1524-475x.2011.00673.x
Autor:
Irene Krukovets, Carla Drumm, Ella G. Frolova, Lauren Blech, Elzbieta Pluskota, Jonathan D. Smith, Olga I. Stenina, Paul Bornstein, Edward F. Plow, Maria Febbraio, Tim Burke
Publikováno v:
Circulation Research. 107:1313-1325
Rationale: Thrombospondin (TSP)-4 is an extracellular protein that has been linked to several cardiovascular pathologies. However, a role for TSP-4 in vascular wall biology remains unknown. Objective: We have examined the effects of TSP-4 gene ( Thbs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5979450106716af08c385027bbb13c08
https://doi.org/10.1161/circresaha.110.232371
https://doi.org/10.1161/circresaha.110.232371
Publikováno v:
Matrix Biology. 29:559-564
The sequence encoding the N-propeptide of collagen I is characterized by significant conservation of amino acids across species; however, the function of the N-propeptide remains poorly defined. Studies in vitro have suggested that one activity of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4597d23da4473113e2dc7244949d2d
https://doi.org/10.1016/j.matbio.2010.08.002
https://doi.org/10.1016/j.matbio.2010.08.002
Autor:
Philip Fleckman, Paul Bornstein, Themis R. Kyriakides, Eleni A. Skokos, Drausin Wulsin, J. Michael Shipley, Annalisa Pirrone, Robert M. Senior
Publikováno v:
Matrix Biology. 28:65-73
Matrix metalloproteinase- (MMP-9) is involved in processes that occur during cutaneous wound healing such as inflammation, matrix remodeling, and epithelialization, To investigate its role in healing, full thickness skin wounds were made in the dorsa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50296f6584459b42ba216ba0b349fbe6
https://doi.org/10.1016/j.matbio.2009.01.001
https://doi.org/10.1016/j.matbio.2009.01.001
Autor:
Robert M. Senior, Themis R. Kyriakides, Dana H. Zhu, Paul Bornstein, J. Michael Shipley, Eleni A. Skokos, Norman A. Meznarich, Sana Raoof, Susan MacLauchlan
Publikováno v:
Journal of Leukocyte Biology. 85:617-626
Macrophages undergo fusion to form multinucleated giant cells in several pathologic conditions, including the foreign body response (FBR). We detected high levels of matrix metalloproteinase (MMP)-9 during macrophage fusion in vitro and in foreign bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3ed8ea4aa9a19f76a787affad63d3b
https://doi.org/10.1189/jlb.1008588
https://doi.org/10.1189/jlb.1008588
Autor:
Karen L. Posey, Jacqueline T. Hecht, Jack Lawler, Paul Bornstein, Kurt D. Hankenson, Alka C. Veerisetty
Publikováno v:
The American Journal of Pathology. 172:1664-1674
Thrombospondin-5 (TSP5) is a large extracellular matrix glycoprotein found in musculoskeletal tissues. TSP5 mutations cause two skeletal dysplasias, pseudoachondroplasia and multiple epiphyseal dysplasia; both show a characteristic growth plate pheno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2edaaf8c7374d5cded1abb45801387
https://doi.org/10.2353/ajpath.2008.071094
https://doi.org/10.2353/ajpath.2008.071094
Publikováno v:
Journal of the American Society of Nephrology. 18:788-798
The role of thrombospondin 2 (TSP2) was investigated in an anti-glomerular basement membrane (GBM) nephritis model that compared TSP2-null mice with wild-type (WT) controls. TSP2-null mice were analyzed for kidney function, renal cortical matrix expa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce83ad0fe493d5f34f6d8f1695c5703
https://doi.org/10.1681/asn.2006080873
https://doi.org/10.1681/asn.2006080873