Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Paul, Blount"'
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/ab0f08beaac64275b12b669dc7abc2ea
Publikováno v:
Microorganisms, Vol 11, Iss 9, p 2236 (2023)
Understanding how bacteria respond to ventilated environments is a crucial concept, especially when considering accurate airflow modeling and detection limits. To properly design facilities for aseptic conditions, we must minimize the parameters for
Externí odkaz:
https://doaj.org/article/c7a4cbdaae474852b38c19424f7dc057
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010198 (2021)
Curcumin, a natural compound isolated from the rhizome of turmeric, has been shown to have antibacterial properties. It has several physiological effects on bacteria including an apoptosis-like response involving RecA, membrane permeabilization, inhi
Externí odkaz:
https://doaj.org/article/24fa9d6a4f254411ba71ae3cb1cf85f0
Publikováno v:
Antibiotics, Vol 11, Iss 7, p 970 (2022)
Resistance to antibiotics is a serious and worsening threat to human health worldwide, and there is an urgent need to develop new antibiotics that can avert it. One possible solution is the development of compounds that possess multiple modes of acti
Externí odkaz:
https://doaj.org/article/affea55ca0824b4b967f21ebf8d1cd3f
Autor:
Limin Yang, Claudio Catalano, Yunyao Xu, Weihua Qiu, Dongyu Zhang, Ann McDermott, Youzhong Guo, Paul Blount
Publikováno v:
BBA Advances, Vol 1, Iss , Pp 100011- (2021)
Proteoliposomes mimic the cell membrane environment allowing for structural and functional membrane protein analyses as well as antigen presenting and drug delivery devices. To make proteoliposomes, purified functional membrane proteins are required.
Externí odkaz:
https://doaj.org/article/4ae51f37a0f748b5b91891233552e71f
In Silico Screen Identifies a New Family of Agonists for the Bacterial Mechanosensitive Channel MscL
Publikováno v:
Antibiotics, Vol 11, Iss 4, p 433 (2022)
MscL is a highly conserved mechanosensitive channel found in the majority of bacterial species, including pathogens. It functions as a biological emergency release valve, jettisoning solutes from the cytoplasm upon acute hypoosmotic stress. It opens
Externí odkaz:
https://doaj.org/article/632c3cf163bb4c4aa342c0478ca96d61
Publikováno v:
Membranes, Vol 11, Iss 11, p 849 (2021)
Mechanosensitive channels respond to mechanical forces exerted on the cell membrane and play vital roles in regulating the chemical equilibrium within cells and their environment. High-resolution structural information is required to understand the g
Externí odkaz:
https://doaj.org/article/d6ef261896024b6c834f3ab697fff4a4
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0228153 (2020)
The antibiotic resistance crisis is becoming dire, yet in the past several years few potential antibiotics or adjuvants with novel modes of action have been identified. The bacterial mechanosensitive channel of large conductance, MscL, found in the m
Externí odkaz:
https://doaj.org/article/f1592b91f46b4c6dbc00116562faa9ce
Autor:
Tubagus Aryandi Gunawan, Alessandro Singlitico, Paul Blount, James Burchill, James G. Carton, Rory F. D. Monaghan
Publikováno v:
Energies, Vol 13, Iss 7, p 1798 (2020)
The results of a techno-economic model of distributed wind-hydrogen systems (WHS) located at each existing wind farm on the island of Ireland are presented in this paper. Hydrogen is produced by water electrolysis from wind energy and backed up by gr
Externí odkaz:
https://doaj.org/article/e1ad8bf51a39491cae935be0b7961f02
Publikováno v:
Biosensors, Vol 3, Iss 1, Pp 171-184 (2013)
The mechanosensitive channel of large conductance, MscL, has been proposed as a triggered nanovalve to be used in drug release and other nanodevices. It is a small homopentameric bacterial protein that has the largest gated pore known: greater than 3
Externí odkaz:
https://doaj.org/article/3c846857c58944d98845d242eb13166f