Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Paul, Bertone"'
Autor:
Navneet Singh, Carsten Eickhoff, Augusto Garcia-Agundez, Paul Bertone, Sunita S. Paudel, Dhananjay T. Tambe, Leslie A. Litzky, Katherine Cox-Flaherty, James R. Klinger, Sean F. Monaghan, Christopher J. Mullin, Mandy Pereira, Thomas Walsh, Mary Whittenhall, Troy Stevens, Elizabeth O. Harrington, Corey E. Ventetuolo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Pulmonary arterial hypertension (PAH) is characterized by endothelial cell (EC) dysfunction. There are no data from living patients to inform whether differential gene expression of pulmonary artery ECs (PAECs) can discern disease subtypes,
Externí odkaz:
https://doaj.org/article/fe02a15d8bc348fbaf794a7a71a2d29c
Autor:
Max Petersen, Anna Chorzalska, Makayla Pardo, Anaelena Rodriguez, John Morgan, Nagib Ahsan, Ting C. Zhao, Olin Liang, Leszek Kotula, Paul Bertone, Philip A. Gruppuso, Patrycja M. Dubielecka
Publikováno v:
Molecular Oncology, Vol 17, Iss 11, Pp 2356-2379 (2023)
Dysregulation of the adaptor protein Abelson interactor 1 (ABI1) is linked to malignant transformation. To interrogate the role of ABI1 in cancer development, we mapped the ABI1 interactome using proximity‐dependent labeling (PDL) with biotin follo
Externí odkaz:
https://doaj.org/article/9feb2424ca384d45925ebb57c2e9eae4
Autor:
Vivien, Marx
Publikováno v:
Nature methods. 10(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe5705af111c58016f3175cb8e4c9945
https://pubmed.ncbi.nlm.nih.gov/27205877
https://pubmed.ncbi.nlm.nih.gov/27205877
Autor:
Céline Labouesse, Bao Xiu Tan, Chibeza C. Agley, Moritz Hofer, Alexander K. Winkel, Giuliano G. Stirparo, Hannah T. Stuart, Christophe M. Verstreken, Carla Mulas, William Mansfield, Paul Bertone, Kristian Franze, José C. R. Silva, Kevin J. Chalut
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The independent control of substrate stiffness and tethering of extracellular matrix to substrates for mechanical signalling investigations remains challenging. Here the authors present StemBond hydrogels, with stable ECM tethering that can be varied
Externí odkaz:
https://doaj.org/article/2711320dd2f24be2b2c8cdd0355b3ae1
Autor:
Vivien Marx
Publikováno v:
Nature Methods. 10:1137-1137
Software can be like music, but an evaluation of software tools can involve some hard-to-play chords.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6456c9ffe0729af1afb878758906a0b
https://doi.org/10.1038/nmeth.2747
https://doi.org/10.1038/nmeth.2747
Autor:
Kathryn C. Tremble, Giuliano G. Stirparo, Lawrence E. Bates, Katsiaryna Maskalenka, Hannah T. Stuart, Kenneth Jones, Amanda Andersson-Rolf, Aliaksandra Radzisheuskaya, Bon-Kyoung Koo, Paul Bertone, José C.R. Silva
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102153- (2021)
Summary: Induced pluripotency provides a tool to explore mechanisms underlying establishment, maintenance, and differentiation of naive pluripotent stem cells (nPSCs). Here, we report that self-renewal of nPSCs requires minimal Sox2 expression (Sox2-
Externí odkaz:
https://doaj.org/article/0ba31fc74d5742b49d4349e5fd86f383
Akademický článek
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Autor:
Ge Guo, Ferdinand von Meyenn, Fatima Santos, Yaoyao Chen, Wolf Reik, Paul Bertone, Austin Smith, Jennifer Nichols
Publikováno v:
Stem Cell Reports, Vol 6, Iss 4, Pp 437-446 (2016)
Conventional generation of stem cells from human blastocysts produces a developmentally advanced, or primed, stage of pluripotency. In vitro resetting to a more naive phenotype has been reported. However, whether the reset culture conditions of selec
Externí odkaz:
https://doaj.org/article/dffb88be6d4f4f50b7ef44d64e28f6ae
Autor:
Helena Carén, Stefan H. Stricker, Harry Bulstrode, Sladjana Gagrica, Ewan Johnstone, Thomas E. Bartlett, Andrew Feber, Gareth Wilson, Andrew E. Teschendorff, Paul Bertone, Stephan Beck, Steven M. Pollard
Publikováno v:
Stem Cell Reports, Vol 5, Iss 5, Pp 829-842 (2015)
Glioblastoma (GBM) is an aggressive brain tumor whose growth is driven by stem cell-like cells. BMP signaling triggers cell-cycle exit and differentiation of GBM stem cells (GSCs) and, therefore, might have therapeutic value. However, the epigenetic
Externí odkaz:
https://doaj.org/article/018195e881b74e3099bb5cf8e7096814