Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Paul, B. G."'
Autor:
Doré, H., Eisenberg, A. R., Junkins, E. N., Leventhal, G. E., Ganesh, Anakha, Cordero, O. X., Paul, B. G., Valentine, D. L., O'Malley, M. A., Wilbanks, E. G.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 2/27/2024, Vol. 121 Issue 9, p1-12, 32p
Conformational Dynamics of DNA Binding and Cas3 Recruitment by the CRISPR RNA-Guided Cascade Complex
Autor:
Angela Patterson, Luke Berry, Brittney L. Forsman, Ravi Kant, Sarah Golden, Joshua Carter, Ryan N. Jackson, Blake Wiedenheft, Paul B. G. van Erp, Brian Bothner
Publikováno v:
ACS Chemical Biology. 13:481-490
Bacteria and archaea rely on CRISPR (clustered regularly interspaced short palindromic repeats) RNA-guided adaptive immune systems for sequence specific elimination of foreign nucleic acids. In Escherichia coli, short CRISPR-derived RNAs (crRNAs) ass
Autor:
Fran Ding, Blake Wiedenheft, Scott Bailey, Ailong Ke, Robert P. Hayes, Yibei Xiao, Kanagalaghatta R. Rajashankar, Paul B. G. van Erp
Publikováno v:
Nature. 530:499-503
Clustered regularly interspaced short palindromic repeats (CRISPRs) and the cas (CRISPR-associated) operon form an RNA-based adaptive immune system against foreign genetic elements in prokaryotes. Type I accounts for 95% of CRISPR systems, and has be
Autor:
Blake Wiedenheft, Ryan N. Jackson, Paul B. G. van Erp, Sarah Golden, Scott Bailey, Joshua Carter
Publikováno v:
Nucleic Acids Research
In bacteria and archaea, short fragments of foreign DNA are integrated into Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) loci, providing a molecular memory of previous encounters with foreign genetic elements. In Escherichia coli
Publikováno v:
Current opinion in microbiology. 37
Adaptive immune systems in bacteria and archaea rely on small CRISPR-derived RNAs (crRNAs) to guide specialized nucleases to foreign nucleic acids. The activation of these nucleases is controlled by a series of molecular checkpoints that ensure preci
Akademický článek
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Autor:
Remus T. Dame, Renko de Vries, Edze R. Westra, Raymond H.J. Staals, Stan J. J. Brouns, Willem M. de Vos, Matthijs M. Jore, Ekaterina Semenova, Christel L.C. Seegers, Tim Künne, John van der Oost, Shi Pey Wong, Sander Bollen, Konstantin Severinov, Paul B. G. van Erp
Publikováno v:
Molecular Cell 46 (2012) 5
Molecular Cell, 46(5), 595-605
Molecular Cell, 46(5), 595-605
Summary The prokaryotic CRISPR/Cas immune system is based on genomic loci that contain incorporated sequence tags from viruses and plasmids. Using small guide RNA molecules, these sequences act as a memory to reject returning invaders. Both the Casca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55bc28d06f8d2762012a73f04c6074e
https://doi.org/10.1016/j.molcel.2012.03.018
https://doi.org/10.1016/j.molcel.2012.03.018
Akademický článek
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Conformational Dynamics of DNA Binding and Cas3 Recruitment by the CRISPR RNA-Guided Cascade Complex
Autor:
van Erp, Paul B. G., Patterson, Angela, Kant, Ravi, Berry, Luke, Golden, Sarah M., Forsman, Brittney L., Carter, Joshua, Jackson, Ryan N., Bothner, Brian, Wiedenheft, Blake
Publikováno v:
ACS Chemical Biology; 20240101, Issue: Preprints
Autor:
Stan J. J. Brouns, Sarah Golden, Thomas C. Terwilliger, Paul B. G. van Erp, Edze R. Westra, John van der Oost, Ryan N. Jackson, Blake Wiedenheft, Randy J. Read, Joshua Carter
Publikováno v:
Science 345 (2014) 6203
Science, 345(6203), 1473-1479
Science, 345(6203), 1473-1479
A foreign-DNA–destroying machine Bacteria have an adaptive immune system, called CRISPR, that identifies invading viruses through their DNA or RNA sequences and cuts them up (see the Perspective by Zhang and Sontheimer). Jackson et al. and Mulepati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c634e179bc4628f543a61f3497484870
https://research.wur.nl/en/publications/crystal-structure-of-the-crispr-rnaguided-surveillance-complex-fr
https://research.wur.nl/en/publications/crystal-structure-of-the-crispr-rnaguided-surveillance-complex-fr