The Oscillatory Profile Induced by the Anxiogenic Drug FG-7142 in the Amygdala–Hippocampal Network Is Reversed by Infralimbic Deep Brain Stimulation: Relevance for Mood Disorders

Autor: Hanna Vila-Merkle, Alicia González-Martínez, Rut Campos-Jiménez, Joana Martínez-Ricós, Vicent Teruel-Martí, Arantxa Blasco-Serra, Ana Lloret, Pau Celada, Ana Cervera-Ferri

Publikováno v: Biomedicines, Vol 9, Iss 7, p 783 (2021)

Anxiety and depression exhibit high comorbidity and share the alteration of the amygdala–hippocampal–prefrontal network, playing different roles in the ventral and dorsal hippocampi. Deep brain stimulation of the infralimbic cortex in rodents or

Externí odkaz: https://doaj.org/article/2259cdce7e8c45caad00629422cae2fa

Dual 5-HT3 and 5-HT6 Receptor Antagonist FPPQ Normalizes Phencyclidine-Induced Disruption of Brain Oscillatory Activity in Rats

Autor: Anna Castañé, Montserrat Cano, Luis Ruiz-Avila, Lluís Miquel-Rio, Pau Celada, Francesc Artigas, Maurizio S Riga

Publikováno v: The international journal of neuropsychopharmacology. 25(5)

Schizophrenia is a severe mental disorder featuring psychotic, depressive, and cognitive alterations. Current antipsychotic drugs preferentially target dopamine D2-R and/or serotonergic 5-HT2A/1A-R. They partly alleviate psychotic symptoms but fail t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44cf8473a5cbef363ac975696195672
https://pubmed.ncbi.nlm.nih.gov/35022720

Modulation of thalamo-cortical activity by the NMDA receptor antagonists ketamine and phencyclidine in the awake freely-moving rat

Autor: Kjartan F. Herrik, Pau Celada, Ulrike Richter, Niels Plath, Anders A. Jensen, Maria Amat-Foraster, Francesc Artigas

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Amat-Foraster, M, Celada, P, Richter, U, Jensen, A A, Plath, N, Artigas, F & Herrik, K F 2019, ' Modulation of thalamo-cortical activity by the NMDA receptor antagonists ketamine and phencyclidine in the awake freely-moving rat ', Neuropharmacology, vol. 158, 107745 . https://doi.org/10.1016/j.neuropharm.2019.107745

Non-competitive N-methyl-D-aspartate receptor antagonists mimic schizophrenia symptoms and produce immediate and persistent antidepressant effects. We investigated the effects of ketamine and phencyclidine (PCP) on thalamo-cortical network activity i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b27811bdd0f6e28a8ccff1861b0c106f
https://pubmed.ncbi.nlm.nih.gov/31445017

Can we increase the speed and efficacy of antidepressant treatments? Part II. Glutamatergic and RNA interference strategies

Autor: Pau Celada, Francesc Artigas, Analía Bortolozzi

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

In the second part we focus on two treatment strategies that may overcome the main limitations of current antidepressant drugs. First, we review the experimental and clinical evidence supporting the use of glutamatergic drugs as fast-acting antidepre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c493e2b16b14be26a7e68904cb97487
http://hdl.handle.net/10261/176419

Temporally dissociable effects of ketamine on neuronal discharge and gamma oscillations in rat thalamo-cortical networks

Autor: Niels Plath, Kjartan F. Herrik, Pau Celada, Maria Amat-Foraster, Francesc Artigas, Anders A. Jensen

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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A partial account of the present study was presented at the 29th Congress of the European College of Neuropsychopharmacology, Vienna 2016 and at the Society for Neuroscience 2017 Annual Meeting.
[Background] Sub-anesthetic doses of the non-compe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6645b2392e15ecb80fb48dd205b7818c
https://pubmed.ncbi.nlm.nih.gov/29702122