Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Pau Bernado"'
Autor:
Nikola Arsic, Tania Slatter, Gilles Gadea, Etienne Villain, Aurelie Fournet, Marina Kazantseva, Frédéric Allemand, Nathalie Sibille, Martial Seveno, Sylvain de Rossi, Sunali Mehta, Serge Urbach, Jean-Christophe Bourdon, Pau Bernado, Andrey V. Kajava, Antony Braithwaite, Pierre Roux
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
p53 isoform Δ133p53β is reported to promote intrinsic oncogenic functions. Here the authors show Δ133p53β is sequestered as aggregates in an inactive form, while association with interacting partners including p63 isoforms and the CCT chaperone c
Externí odkaz:
https://doaj.org/article/68225466d9dc4ec1bb5844837f0a0ec8
Autor:
Juan Manuel Valverde, Geronimo Dubra, Michael Phillips, Austin Haider, Carlos Elena-Real, Aurélie Fournet, Emile Alghoul, Dhanvantri Chahar, Nuria Andrés-Sanchez, Matteo Paloni, Pau Bernadó, Guido van Mierlo, Michiel Vermeulen, Henk van den Toorn, Albert J. R. Heck, Angelos Constantinou, Alessandro Barducci, Kingshuk Ghosh, Nathalie Sibille, Puck Knipscheer, Liliana Krasinska, Daniel Fisher, Maarten Altelaar
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Cell cycle transitions result from global changes in protein phosphorylation states triggered by cyclin-dependent kinases (CDKs). To understand how this complexity produces an ordered and rapid cellular reorganisation, we generated a high-re
Externí odkaz:
https://doaj.org/article/e9908b9e43c84a22ae719efb78f9bc6b
Autor:
Paula M. Corsini, Sunjun Wang, Saima Rehman, Katherine Fenn, Amin Sagar, Slobodan Sirovica, Leanne Cleaver, Charlotte J. C. Edwards-Gayle, Giulia Mastroianni, Ben Dorgan, Lee M. Sewell, Steven Lynham, Dinu Iuga, W. Trent Franks, James Jarvis, Guy H. Carpenter, Michael. A. Curtis, Pau Bernadó, Vidya C. Darbari, James A. Garnett
Publikováno v:
npj Biofilms and Microbiomes, Vol 8, Iss 1, Pp 1-16 (2022)
Abstract Escherichia coli is a Gram-negative bacterium that colonises the human intestine and virulent strains can cause severe diarrhoeal and extraintestinal diseases. The protein SslE is secreted by a range of pathogenic and commensal E. coli strai
Externí odkaz:
https://doaj.org/article/747f5f7c49064702a50bcc94f3a5b325
Autor:
Belén Chaves-Arquero, Santiago Martínez-Lumbreras, Nathalie Sibille, Sergio Camero, Pau Bernadó, M. Ángeles Jiménez, Silvia Zorrilla, José Manuel Pérez-Cañadillas
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Yeast eIF4G1 interacts with RNA binding proteins (RBPs) like Pab1 and Pub1 affecting its function in translation initiation and stress granules formation. We present an NMR and SAXS study of the N-terminal intrinsically disordered region of eIF4G1 (r
Externí odkaz:
https://doaj.org/article/7d78a4554f9246158f89bef1a4df1e84
Autor:
Min-Kyu, Cho, Gabrielle, Nodet, Hai-Young, Kim, Malene R, Jensen, Pau, Bernado, Claudio O, Fernandez, Stefan, Becker, Martin, Blackledge, Markus, Zweckstetter
Publikováno v:
Protein science : a publication of the Protein Society. 18(9)
The relation of alpha-synuclein (alphaS) aggregation to Parkinson's disease has long been recognized, but the pathogenic species and its molecular properties have yet to be identified. To obtain insight into the properties of alphaS in an aggregation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ba349322c538d84206130e2d40bde88
https://pubmed.ncbi.nlm.nih.gov/19554627
https://pubmed.ncbi.nlm.nih.gov/19554627
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3817-3828 (2021)
Intrinsically Disordered Proteins and Regions (IDPs/IDRs) are key components of a multitude of biological processes. Conformational malleability enables IDPs/IDRs to perform very specialized functions that cannot be accomplished by globular proteins.
Externí odkaz:
https://doaj.org/article/30613164330e491497aac99f6eade2d8
Autor:
Miquel Pons, Pau Bernado
Publikováno v:
ChemInform. 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0661432d0dd1cb54c3d4c2f442adf54c
https://doi.org/10.1002/chin.200327292
https://doi.org/10.1002/chin.200327292
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 306-313 (2020)
Polyglutamine (polyQ) regions are one of the most prevalent homorepeats in eukaryotes. It is however difficult to evaluate their prevalence because various studies claim different results. The reason is the lack of a consensus to define what is indee
Externí odkaz:
https://doaj.org/article/958bef9fa3e44dd0801ad5a6e23a00a0
Autor:
Mariane Gonçalves-Kulik, Pablo Mier, Kristina Kastano, Juan Cortés, Pau Bernadó, Friederike Schmid, Miguel A. Andrade-Navarro
Publikováno v:
Biomolecules, Vol 12, Iss 8, p 1098 (2022)
There is increasing evidence that many intrinsically disordered regions (IDRs) in proteins play key functional roles through interactions with other proteins or nucleic acids. These interactions often exhibit a context-dependent structural behavior.
Externí odkaz:
https://doaj.org/article/20014d754a23449593daf21bb349a3fa
Autor:
Myriam Guillien, Assia Mouhand, Aurélie Fournet, Amandine Gontier, Aleix Martí Navia, Tiago N. Cordeiro, Frédéric Allemand, Aurélien Thureau, Jean-Louis Banères, Pau Bernadó, Nathalie Sibille
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 617 (2022)
Arrestin-dependent pathways are a central component of G protein-coupled receptor (GPCRs) signaling. However, the molecular processes regulating arrestin binding are to be further illuminated, in particular with regard to the structural impact of GPC
Externí odkaz:
https://doaj.org/article/1595edf4faf3410b84a10f7e944cbad6