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Autor:
Takao Kodera, Tracy L. McGaha, Constantin A. Bona, Hilde Cheroute, Patty Zwolo, Dorel L. Radu, Cristina Stoica, Roberta R. Pollock
Publikováno v:
Genes to cells : devoted to molecularcellular mechanisms. 9(11)
Somatic mutation of immunoglobulin (Ig) genes plays an important role in generating antibody diversity. The frequency of somatic mutation appears to vary throughout life. However, this process has been difficult to study in vivo because the DNA in an