Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Patty Wong"'
Autor:
Lindsay Williams, Lin Li, Paul J. Yazaki, Patty Wong, Teresa Hong, Erasmus K. Poku, Susanta Hui, Hemendra Ghimire, John E. Shively, Maciej Kujawski
Publikováno v:
Cancer Medicine, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract Background The potent immune effects of interleukin‐2 (IL‐2) for cancer therapy can be increased by genetic fusion of IL‐2 to the Fc domain of an antibody (IL‐2‐Fc) or tumor targeted by genetic fusion to a whole antibody known as a
Externí odkaz:
https://doaj.org/article/5d59608a2bfc41f3848415e9d3c06ce0
Development and characterization of DIA 12.3, a fully human intact anti-CEACAM1 monoclonal antibody.
Autor:
Michela Centonze, Valentina Fiori, Maciej Kujawski, Lin Li, Patty Wong, Lindsay Williams, Tomas Di Mambro, Sabrina Dominici, Angelo Sparti, John E Shively, Mauro Magnani
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0295345 (2024)
Carcinoembryonic antigen cell adhesion molecule-1 (CEACAM1), a homotypic cell adhesion molecule glycoprotein with apical expression on normal epithelial cells and activated lymphocytes, is overexpressed on many tumors and acts as an inhibitory recept
Externí odkaz:
https://doaj.org/article/b51ad4ff63384ac8a4df3e97495290ac
Autor:
Junfeng Li, Weidong Hu, Jiangling Peng, Patty Wong, Fouad Kandeel, Tove Olafsen, John E. Shively
Publikováno v:
Pharmaceuticals, Vol 15, Iss 12, p 1577 (2022)
The world-wide high incidence of non-alcoholic fatty liver disease (NAFLD) is of concern for its progression to insulin resistance, steatohepatitis and cardiovascular disease (CVD). The increased uptake of fatty acids in critical organs plays a major
Externí odkaz:
https://doaj.org/article/3f9c736a80a54457bdf7222f4732c34c
Autor:
Maciej Kujawski, Lin Li, Supriyo Bhattacharya, Patty Wong, Wen-Hui Lee, Lindsay Williams, Harry Li, Junie Chea, Kofi Poku, Nicole Bowles, Nagarajan Vaidehi, Paul Yazaki, John E. Shively
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background Bispecific T-cell engaging antibodies (BiTES), comprising dual anti-CD3 and anti-tumor antigen scFv fragments, are important therapeutic agents for the treatment of cancer. The dual scFv construct for BiTES requires proper protein
Externí odkaz:
https://doaj.org/article/ac867d27e03b48d49a75f75d86b0177f
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84515 (2013)
Histone deacetylase inhibitors (HDIs) have shown promise as candidate radiosensitizer for many types of cancers. However, the mechanisms of action are not well understood, and whether they could have clinical impact on radiotherapy for leukemia is un
Externí odkaz:
https://doaj.org/article/44d2a7bc54194d48a4d7440ee05430ef
Autor:
Jeffrey Y.C. Wong, Corentin Laulier, Jeremy M. Stark, Eric H. Radany, Patty Wong, Xufeng Chen
PDF file - 364K, Cells were pretreated with 200 nM SAHA for 16 hours, and then irradiated with 6 Gy. Cells were collected at indicated time points after irradiation for immunofluorescence staining with anti-RAD51 antibody (red), and anti phosphorylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d94944328634e44eb7b8a78ffb903add
https://doi.org/10.1158/1541-7786.22517026
https://doi.org/10.1158/1541-7786.22517026
Autor:
Jeffrey Y.C. Wong, Corentin Laulier, Jeremy M. Stark, Eric H. Radany, Patty Wong, Xufeng Chen
PDF file - 41K, Dose-dependent cytoxicity of SAHA on Multiple Myeloma cells in vitro. * and ** indicate significances (*Rho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae4250c42ecfd520a9be7e4bfde8b18
https://doi.org/10.1158/1541-7786.22517035
https://doi.org/10.1158/1541-7786.22517035
Autor:
Jeffrey Y.C. Wong, Corentin Laulier, Jeremy M. Stark, Eric H. Radany, Patty Wong, Xufeng Chen
PDF file - 66K, (A) Immunofluorescence analysis for RAD51 (red) and cyclin A (green) co-staining in U266B1 cells at indicated time point after IR; Nuclei were stained with DAPI (blue). (B) Flow Cytometry assays for BrdU-incorporation and cell cycle d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::552da192732faf7ba64fc1107e45c2ae
https://doi.org/10.1158/1541-7786.22517023.v1
https://doi.org/10.1158/1541-7786.22517023.v1
Autor:
Jeffrey Y.C. Wong, Corentin Laulier, Jeremy M. Stark, Eric H. Radany, Patty Wong, Xufeng Chen
PDF file - 60K, Effects of SAHA on (A) IC50/IC90, and (B) acetylation of histone H4 (fold changes measured by densitometry for western blot signals) in Multiple Myeloma cells in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04af791c9ed110169a01cab6993dd9ad
https://doi.org/10.1158/1541-7786.22517038.v1
https://doi.org/10.1158/1541-7786.22517038.v1
Supplementary Figures S1-S5; Supplementary Tables S1-S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8126e1c0400ecbc98a9cd02c833177d6
https://doi.org/10.1158/1541-7786.22519497.v1
https://doi.org/10.1158/1541-7786.22519497.v1