Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Patty I. Mathias"'
Publikováno v:
Environmental Health Perspectives
An effect on intracellular calcium continues to be proposed as a biochemical pathway for the mediation of biologic effects of electrical-power-frequency magnetic fields (MF). However, reproducible results among laboratories are difficult to attain an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d2cf55bb53f3f4812b53c2779fe966
https://doi.org/10.1289/ehp.00108135
https://doi.org/10.1289/ehp.00108135
Publikováno v:
Toxicology. 119:203-211
Cultured cardiac myocytes were exposed for up to 4 h to 50 and 100 microM potassium antimonyl tartrate (PAT). After 4 h, 50 and 100 microM PAT killed 14 and 33% respectively of the cardiac myocytes. PAT-induced alterations in both protein and nonprot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd70ab051599a58e844790c1f1ee5f6
https://doi.org/10.1016/s0300-483x(97)03628-7
https://doi.org/10.1016/s0300-483x(97)03628-7
Autor:
Mark Toraason, Ingrid Heinroth-Hoffmann, Donald E. Richards, P. Hoffmann, H.E. Wey, Patty I. Mathias
Publikováno v:
Cardiovascular Research. 30:889-898
Objectives: The purpose of this study was to investigate the effects of prolonged arachidonic acid (AA) exposure on electrically induced fluctuations of cytosolic free Ca2+ concentration ([Ca2+]i) in cardiac myocytes and to identify intracellular bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a3acbcc67b150f4b2caa3c06515299a
https://doi.org/10.1016/s0008-6363(95)00133-6
https://doi.org/10.1016/s0008-6363(95)00133-6
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 34:19-21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2b8528f72e006395b161858476303e
https://doi.org/10.1007/s11626-998-0045-6
https://doi.org/10.1007/s11626-998-0045-6
Autor:
Mary Ann Butler, Patty I. Mathias, Kenneth L. Cheever, Howard Wey, Kate L. Marlow, Avima M. Ruder, Lauralynn Taylor, Christy Forrester, David L Ashley, Mark Toraason, Edward F. Krieg
Publikováno v:
Mutation research. 539(1-2)
Perchloroethylene (PERC) is used widely as an industrial dry cleaning solvent and metal degreaser. PERC is an animal carcinogen that produces increased incidence of renal adenomas, adenocarcinomas, mononuclear cell leukemia, and hepatocellular tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1bf4048beb26be605d48ada7af29544
https://pubmed.ncbi.nlm.nih.gov/12948810
https://pubmed.ncbi.nlm.nih.gov/12948810
Autor:
David A. Dankovic, Mark Toraason, Dwight Werren, John C. Clark, Patty I. Mathias, Cynthia V. Walker, Steve Skaggs
Publikováno v:
Toxicology. 138(1)
Oxidative DNA damage is emerging as an biomarker of effect in studies assessing the health risks of occupational chemicals. Trichloroethylene (TCE) and perchloroethylene (PERC) are used in the dry cleaning industry and their metabolism can produce re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfca12067f19f1aecdd542357a3e82a
https://pubmed.ncbi.nlm.nih.gov/10566590
https://pubmed.ncbi.nlm.nih.gov/10566590
Publikováno v:
Toxicology and applied pharmacology. 159(2)
The effects of nonlethal concentrations of potassium antimonyl tartrate (PAT) were examined in cultured neonatal rat cardiac myocytes. PAT (5, 10 microM) significantly increased cellular reduced glutathione (GSH) and heme oxygenase activity after 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4fa22554e8222464abf6304c00f785
https://pubmed.ncbi.nlm.nih.gov/10495772
https://pubmed.ncbi.nlm.nih.gov/10495772
Publikováno v:
Electrophoresis. 18(15)
Despite reported adverse effects, the cardiovascular toxicity of lead remains controversial. The purpose of the present study was to determine if low-level subchronic exposure of rabbits to lead would produce detectable, concentration-dependent chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0734caab29db4c63cc1454a38fdfe4
https://pubmed.ncbi.nlm.nih.gov/9504838
https://pubmed.ncbi.nlm.nih.gov/9504838
Publikováno v:
Toxicology and applied pharmacology. 146(1)
Industrial exposure and pharmaceutical use of antimony compounds have been linked to altered cardiovascular function and pathology. Antimony compounds induce hypotension, bradycardia, and cardiac arrhythmias, all of which can arise from aberrations i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a531c20f8f938d36a79cebe46ea39d3
https://pubmed.ncbi.nlm.nih.gov/9299602
https://pubmed.ncbi.nlm.nih.gov/9299602
Publikováno v:
Toxicology and applied pharmacology. 145(1)
Trivalent antimony, delivered as potassium antimonyl tartrate (PAT), has been previously shown to induce an oxidative stress and toxicity in cultured neonatal rat cardiac myocytes. The present study investigates the effect of PAT on intracellular fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb35c9a7474b61739d5b641f3007047
https://pubmed.ncbi.nlm.nih.gov/9221838
https://pubmed.ncbi.nlm.nih.gov/9221838