Výsledky vyhledávání - "Patton, W. F."

P216-T Beyond Differential In-Gel Electrophoresis: Top-down Multiplexed Analysis in Two-dimensional Gels Using an Isobaric Mass Tagging Approach

Autor: Xie, B., Hekking, B., Lisoukov, H., Wang, Y., Parman, C., Patton, W. F.

Large sets of biological samples are commonly encountered in biomedical research, and a rigorous, reliable top-down quantification method for proteins from multiple samples is required. With differential in-gel electrophoresis (DIGE), Cy3 and Cy5 dye

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmc_________::5c44f8185caaaa5cec3edf72acfcb901
https://europepmc.org/articles/PMC2291894/

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P75-T Selective Detection of Phosphoproteins and Subsequent Enrichment of Constituent Phosphopeptides for Phosphorylation Site Analysis by Mass Spectrometry

Autor: Mikulskis, A., Kramer, S. E., Bogdanova, A., Xie, H., Golenko, E., Wang, Y., Lisoukov, H., Patton, W. F.

Protein phosphorylation is crucial to the global regulation of the intricate biochemical networks of cell signaling pathways, allowing protein functional activity, stability, association into multi-subunit complexes, and subcellular localization to b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmc_________::bb5aafbe19ebb6eeaf30dfa2826633a9
https://europepmc.org/articles/PMC2291898/

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P208-S Top-Down Quantitative Proteomic Analysis Using a Highly Multiplexed Isobaric Mass Tagging Strategy

Autor: Patton, W. F., Xie, B.

Proteomic analysis has proved key to determining drug mechanisms and assessing toxicological potential during preclinical screening studies. A major goal in proteomics is to accurately measure changes in the relative abundance of large sets of protei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmc_________::73a19c8464a2766dec652bfa76a384fa
https://europepmc.org/articles/PMC2292037/

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