Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Pattisapu R. J. Gangadharam"'
Autor:
Pattisapu R. J. Gangadharam, Donald L. Wise, Yung-Yueh Hsu, Joseph D. Gresser, Debra J. Trantolo, Charles M. Lyons
Publikováno v:
Journal of Controlled Release. 40:293-302
Incorporation of the antitubercular drug isoniazid, INH, into low density poly(dl-lactide-co-glycolide), PLGA, foams of high interstitial void volume prior to high pressure extrusion is shown to prolong the in vitro release of INH. In vitro studies i
Autor:
Mahmood Ghassemi, Burton R. Andersen, Venkata M. Reddy, Richard M. Novak, Gregory T. Spear, Pattisapu R. J. Gangadharam
Publikováno v:
Journal of Infectious Diseases. 171:68-73
Disseminated Mycobacterium avium complex (MAC) infection is an important opportunistic infection in AIDS patients. Because cells of macrophage lineage are targets for both human immunodeficiency virus (HIV) and MAC, the monocytoid cell line U937 was
Publikováno v:
Journal of Antimicrobial Chemotherapy. 33:273-279
We have studied the bioavailability of clofazimine following administration of a single dose of the drug in the biodegradable polymer polylactic-co-glycolic acid (PLGA). We compared the levels of clofazimine achieved in the liver with single implants
Publikováno v:
Journal of Controlled Release. 26:87-98
Earlier studies by us have shown that a single subcutaneous implant of isoniazid in polylactic coglycolic acid (PLGA) polymer showed sustained levels of drug release for prolonged periods. These levels are comparable to those attained following daily
Autor:
Pattisapu R. J. Gangadharam, Daniel S. Friend, Diana L. Flasher, Naheed Ghori, Dilip R. Ashtekar, Nejat Düzgüneş, Robert J. Debs
Publikováno v:
Journal of Infectious Diseases. 164:143-151
Current treatments for Mycobacterium avium-intracellulare complex (MAC) infections are generally ineffective. Thus, the potential of free or liposome-encapsulated streptomycin to treat acute MAC infection was investigated in beige mice. Free streptom
Autor:
Kameswari S, Konduri, Sandhya, Nandedkar, David A, Rickaby, Nejat, Düzgüneş, Pattisapu R J, Gangadharam
Publikováno v:
Methods in enzymology. 391
Asthma is characterized by airway hyperresponsiveness, chronic inflammation, and airway remodeling, which may lead to progressive, irreversible lung damage. Liposomes have been used for the delivery of aerosolized asthma medications into the lungs. T
Autor:
K.S. Konduri, Pattisapu R. J. Gangadharam, Vincent Suzara, S.D. Nandedkar, Nejat Düzgüneş, James E. Artwohl, Ralph M. Bunte
Publikováno v:
The Journal of allergy and clinical immunology. 111(2)
Background: Inhaled corticosteroids, such as budesonide, attenuate the inflammatory response in asthma. However, patient noncompliance and side effects of available inhaled corticosteroids limit their use. Liposomes are currently used in medicine to
Autor:
Pattisapu R. J. Gangadharam
Publikováno v:
Mycobacteria ISBN: 9781461377436
From a microbiological point of view, every culture of tubercle bacilli would contain some proportion of mutant organisms which are “resistant” to the drug. Thus, resistance and susceptibility are relative terms. What is generally accepted and wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c5a95947854ed22e630a076694e3218
https://doi.org/10.1007/978-1-4615-5987-0_2
https://doi.org/10.1007/978-1-4615-5987-0_2
Autor:
Pattisapu R. J. Gangadharam
Publikováno v:
Mycobacteria ISBN: 9781461575139
Until the middle of this century, tuberculosis had been a serious and often lifethreatening disease. Starting from the late forties, following the introduction of specific drugs, the disease has been brought rapidly to a stage of a curable one. Even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e8478720fef71099f60b51fd31d3f82
https://doi.org/10.1007/978-1-4615-7511-5_13
https://doi.org/10.1007/978-1-4615-7511-5_13