Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Pattie Hellmann"'
Autor:
Pattie Hellmann, Michael O. Thorner, John J. Kopchick, Karen T. Coschigano, Jianhua Liu, Ralf Nass, Bruce D. Gaylinn, Darlene E. Berryman
Publikováno v:
Journal of Neuroendocrinology. 16:669-675
Ghrelin is an endogenous ligand for the growth hormone secretagogue (GHS) receptor. Ghrelin is involved in feeding behaviour and is a potent stimulator of GH release. Chronically increased GH concentrations are known to negatively regulate the pituit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad9619063b4a08f63367eb612710137
https://doi.org/10.1111/j.1365-2826.2004.01220.x
https://doi.org/10.1111/j.1365-2826.2004.01220.x
Autor:
Bruce D. Gaylinn, Richard V. Clark, Michael O. Thorner, E. Bissonette, Ralf Nass, Andy Toogood, Pattie Hellmann
Publikováno v:
Journal of Neuroendocrinology. 12:1194-1199
Pulsatile growth hormone (GH) secretion is regulated by three hypothalamic factors, growth hormone-releasing hormone (GHRH), somatostatin and the natural ligand for the GH secretagogue receptor (Ghrelin). These factors and their effects are, in turn,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a59f1b8aa999e4803d01e69641b8fb5
https://doi.org/10.1046/j.1365-2826.2000.00586.x
https://doi.org/10.1046/j.1365-2826.2000.00586.x
Publikováno v:
The Journal of clinical endocrinology and metabolism. 81(7)
Spontaneous secretion of GH decreases with aging. To investigate whether fasting increases pulsatile GH secretion in older as it does in younger subjects, we studied six subjects (four postmenopausal women and two men, aged 55-81 yr; body mass indexe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb80271b997bc3221a37dd2c96598e8
https://pubmed.ncbi.nlm.nih.gov/8675598
https://pubmed.ncbi.nlm.nih.gov/8675598
Autor:
Michael O. Thorner, Antonio Torsello, Richard O. Day, Eugenio E. Muller, Pattie Hellmann, Reiko Horikawa, Silvano G. Cella
Recent studies have demonstrated that passive immunization of neonatal rats to GRF inhibited their somatic growth through the suppression of GH secretion. In this study, we investigated the changes in pituitary GRF receptor (GRFR) expression in GRF a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da04dbe291f86274a70a67a3e9d481b
http://hdl.handle.net/10281/38462
http://hdl.handle.net/10281/38462
Autor:
José A. Burdman, Michael O. Thorner, Kalman Kovacs, Dorothy Scott, Pattie Hellmann, D. J. McComb, William S. Evans
Publikováno v:
Neuroendocrinology. 41:201-211
The effect of bromocriptine (BEC) treatment on spontaneous, sparsely granulated, prolactin-producing pituitary adenomas was studied in aging female Long-Evans rats of at least 23 months of age. Rats treated with BEC for 1-44 days showed a marked decr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c990f36e64eb1d2534d04c03e1e4666a
https://doi.org/10.1159/000124179
https://doi.org/10.1159/000124179
Autor:
Pattie Hellmann, William S. Evans, Donald L. Kaiser, Michael O. Thorner, David R. Uskavitch, Joao L. C. Borges
Publikováno v:
Endocrinology. 114:861-867
To study in vitro the self-priming effect of GnRH on LH release, rat anterior pituitaries were prepared either as fragments or dispersed cells and continuously perifused in parallel chambers. The experimental groups consisted of rats killed at 0800 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e7a37b16f3afd58198b0d3eb93e2d8
https://doi.org/10.1210/endo-114-3-861
https://doi.org/10.1210/endo-114-3-861
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 175(2)
The action of the potent dopamine receptor agonist bromocriptine was studied in primary cultures of rat anterior pituitary cells. Bromocriptine inhibited both prolactin and growth hormone release in a concentration-dependent manner. This effect was b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ac15efb217aa22aa698b12cbe8c6f5
https://pubmed.ncbi.nlm.nih.gov/6694976
https://pubmed.ncbi.nlm.nih.gov/6694976
Publikováno v:
Experimental pathology. 26(3)
Old female Long-Evans rats with elevated serum prolactin levels were used to study the effect of bromocriptine on the stimulated mammary glands by histology, electron microscopy, and morphometry. Untreated rats were divided into normoprolactinemic (b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12aab169fec9c6168cb45bb074a90304
https://pubmed.ncbi.nlm.nih.gov/6542869
https://pubmed.ncbi.nlm.nih.gov/6542869
Autor:
Pattie Hellmann, Aubrey E. Boyd, Michael O. Thorner, Jennifer L. Thominet, Wylie Vale, Marcus Schaaf, William G. Blackard, Christopher R. W. Edwards, G. Michael Besser, Dorothy T. Krieger, Thomas R. Downs, N. Lytras, Nancy J. Charest, Shlomo Melmed, Marie C. Gelato, Sorana Marcovitz, George Prioleau, Eloy Ituarte, William B. Malarkey, Lawrence A. Frohman, Joan Vaughan, Denis A. Leong, Jean Chitwood
Publikováno v:
The Journal of clinical endocrinology and metabolism. 59(5)
To assess the frequency with which acromegaly is caused by ectopic secretion of GRF, we collected plasma samples from 177 unselected acromegalic patients. The samples together with those of three acromegalic patients with previously diagnosed tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8a56cfa47e5269ea5bf1de166b6c4c
https://pubmed.ncbi.nlm.nih.gov/6434585
https://pubmed.ncbi.nlm.nih.gov/6434585