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pro vyhledávání: '"Patti Aha"'
Autor:
Shawn Weng, Lihui Xu, Dasa Lipovsek, Patti Aha, Lin Sun, Robert G. Kuimelis, Terence Lam, Markus Kurz, Richard W. Wagner, Ai Ching Lim, Hongxiang Liu, Ke Gu, Peter A. Lohse
Publikováno v:
Chemistry & Biology. 9:933-942
We constructed a library of >10(12) unique, covalently coupled mRNA-protein molecules by randomizing three exposed loops of an immunoglobulin-like protein, the tenth fibronectin type III domain (10Fn3). The antibody mimics that bound TNF-alpha were i