Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

Autor: Adkins, Amy E, Hack, Laura M, Raabe, Richard C, Alaimo, Joseph T, Blackwell, GinaMari G, Moscati, Arden, Poland, Ryan S, Rood, Benjamin, Patterson, Diana G, Walsh, Dermot, Consortium, Collaborative Study of the Genetics of Alcoholism, Whitfield, John B, Bigdeli, Tim B, Zhu, Gu, Montgomery, Grant W, Henders, Anjali K, Martin, Nicholas G, Heath, Andrew C, Madden, Pamela A F, Frank, Josef, Ridinger, Monika, Wodarz, Norbert, Soyka, Michael, Williamson, Vernell S, Zill, Peter, Ising, Marcus, Nöthen, Markus M, Kiefer, Falk, Rietschel, Marcella, Consortium, German Study of the Genetics of Addiction, Gelernter, Joel, Sherva, Richard, Koesterer, Ryan, Almasy, Laura, McMichael, G Omari, Zhao, Hongyu, Kranzler, Henry R, Farrer, Lindsay A, Maher, Brion S, Prescott, Carol A, Dick, Danielle M, Bacanu, Silviu A, Mathies, Laura D, Davies, Andrew G, Vladimirov, Vladimir I, Mamdani, Mohammed, Grotewiel, Mike, Bowers, M Scott, Bettinger, Jill C, Webb, Bradley T, Miles, Michael F, Kendler, Kenneth S, Riley, Brien P, Hesselbrock, Victor, Bauer, Lance, Chan, Grace, Edwards, Alexis C, Edenberg, Howard J, Xuei, Xiaoling, Nurnberger, John, O'Connor, Sean, Foroud, Tatiana, Koller, Daniel L, Wetherill, Leah, Kuperman, Samuel, Kramer, John, Porjesz, Bernice, Aliev, Fazil, Kang, Sun J, Manz, Niklas, Rangaswamy, Madhavi, Bierut, Laura, Rice, John, Bucholz, Kathleen, Rohrbaugh, John W, Wang, Jen C, Goate, Alison, Schuckit, Marc, Chan, Robin F, Tischfield, Jay, Brooks, Andrew, Taylor, Robert E, Cichon, Sven, Treutlein, Jens, Mattheisen, Manuel, Hoffmann, Per, Herms, Stefan, Maier, Wolfgang, Mössner, Rainald, Bhandari, Poonam, Degenhardt, Franziska, Gaebel, Wolfgang, Dahmen, Norbert, Scherbaum, Norbert, Schmäl, Christine, Steffens, Michael, Lucae, Susanne, Müller-Myhsok, Bertram, Mann, Karl

Publikováno v: Alcoholism 41(5), 911-928 (2017). doi:10.1111/acer.13362
Alcoholism: Clinical and Experimental Research

Background: Alcohol dependence (AD) shows evidence for genetic liability, but genes influencing risk remain largely unidentified. Methods: We conducted a genomewide association study in 706 related AD cases and 1,748 unscreened population controls fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137212ea846579aaa546f823b50ff37f
https://www.ncbi.nlm.nih.gov/pubmed/28226201

Genomewide linkage survey of nicotine dependence phenotypes

Autor: Prescott, Carol A., Patterson, Diana G., Neale, Michael C., Walsh, Dermot, Sullivan, Patrick F., Kendler, Kenneth S., Vittum, Jen, Webb, B. Todd, Kuo, Po-Hsiu, Riley, Brien, Furberg, Helena

A comprehensive understanding of the etiology and neurobiology of nicotine dependence is not available. We sought to identify genomic regions that might contain etiologically-relevant loci using genomewide univariate and bivariate linkage analyses.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b402782c645dcdc6c3c5b5543faa8c21

Genome-wide linkage scans for major depression in individuals with alcohol dependence

Autor: Kuo, Po-Hsiu, Neale, Michael C., Walsh, Dermot, Patterson, Diana G., Riley, Brien, Prescott, Carol A., Kendler, Kenneth S.

Publikováno v: In Journal of Psychiatric Research 2010 44(9):616-619

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.