Induction and maintenance of bi-functional (IFN-γ ⁺ IL-2⁺ and IL-2⁺ TNF-α⁺) T cell responses by DNA prime MVA boosted subtype C prophylactic vaccine tested in a Phase I trial in India.

Autor: Munusamy Ponnan, Sivasankaran¹, Pattabiram, Sathyamurthy¹, Thiruvengadam, Kannan¹, Goyal, Rajat², Singla, Nikhil², Mukherjee, Joyeeta², Chatrath, Shweta², Bergin, Philip³, T. Kopycinski, Jakub³, Gilmour, Jill³, Kumar, Sriram¹, Muthu, Malathy¹, Subramaniam, Sudha¹, Swaminathan, Soumya¹, Prasad Tripathy, Srikanth¹, Luke, Hanna Elizabeth¹ hanna@nirt.res.in

Publikováno v: PLoS ONE. 3/28/2019, Vol. 14 Issue 3, p1-23. 23p.

Induction and maintenance of bi-functional (IFN-γ + IL-2+ and IL-2+ TNF-α+) T cell responses by DNA prime MVA boosted subtype C prophylactic vaccine tested in a Phase I trial in India.

Autor: Munusamy Ponnan S; Department of HIV, National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India., Pattabiram S; Department of HIV, National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India., Thiruvengadam K; Department of HIV, National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India., Goyal R; International AIDS Vaccine Initiative, New Delhi, India., Singla N; International AIDS Vaccine Initiative, New Delhi, India., Mukherjee J; International AIDS Vaccine Initiative, New Delhi, India., Chatrath S; International AIDS Vaccine Initiative, New Delhi, India., Bergin P; IAVI Human Immunology Laboratory, Imperial College, London, United Kingdom., T Kopycinski J; IAVI Human Immunology Laboratory, Imperial College, London, United Kingdom., Gilmour J; IAVI Human Immunology Laboratory, Imperial College, London, United Kingdom., Kumar S; Department of HIV, National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India., Muthu M; Department of HIV, National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India., Subramaniam S; Department of HIV, National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India., Swaminathan S; Department of HIV, National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India., Prasad Tripathy S; Department of HIV, National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India., Luke HE; Department of HIV, National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India.

Publikováno v: PloS one [PLoS One] 2019 Mar 28; Vol. 14 (3), pp. e0213911. Date of Electronic Publication: 2019 Mar 28 (Print Publication: 2019).