Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Patryk Ludzia"'
Autor:
Daniel Ballmer, William Carter, Jolien J. E. van Hooff, Eelco C. Tromer, Midori Ishii, Patryk Ludzia, Bungo Akiyoshi
Publikováno v:
Open Biology, Vol 14, Iss 6 (2024)
Faithful transmission of genetic material is crucial for the survival of all organisms. In many eukaryotes, a feedback control mechanism called the spindle checkpoint ensures chromosome segregation fidelity by delaying cell cycle progression until al
Externí odkaz:
https://doaj.org/article/fc51c75b5ea24df384d7b5ae11810b0e
Publikováno v:
Open Biology, Vol 11, Iss 5 (2021)
Chromosome segregation in eukaryotes is driven by the kinetochore, a macromolecular complex that connects centromeric DNA to microtubules of the spindle apparatus. Kinetochores in well-studied model eukaryotes consist of a core set of proteins that a
Externí odkaz:
https://doaj.org/article/c66f3efda2c04e9ab5f0e6aff32869a1
Publikováno v:
Open Biology, Vol 9, Iss 12 (2019)
The kinetochore is a multi-protein complex that drives chromosome segregation in eukaryotes. It assembles onto centromere DNA and interacts with spindle microtubules during mitosis and meiosis. Although most eukaryotes have canonical kinetochore prot
Externí odkaz:
https://doaj.org/article/a84e0a830e2c478993d94374535decde
Divergent polo boxes in KKT2 and KKT3 initiate the kinetochore assembly cascade inTrypanosoma brucei
Autor:
Midori Ishii, Patryk Ludzia, Gabriele Marcianò, William Allen, Olga O. Nerusheva, Bungo Akiyoshi
Chromosome segregation requires assembly of the macromolecular kinetochore complex onto centromeric DNA. While most eukaryotes have canonical kinetochore proteins that are widely conserved among eukaryotes, evolutionarily divergent kinetoplastids hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5c2e124ac78af0cf59665f71c93c0fb
https://doi.org/10.1101/2022.06.02.494600
https://doi.org/10.1101/2022.06.02.494600
Publikováno v:
Biomolecular Nmr Assignments
KKT4 is a kinetoplastid-specific microtubule-binding kinetochore protein that lacks significant similarity to any known kinetochore or microtubule-binding proteins. Here we present the 1H, 13C and 15N resonance assignments for several fragments from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5253b57fb4c4943a1b6724a9cdeaecff
https://doi.org/10.1007/s12104-020-09968-1
https://doi.org/10.1007/s12104-020-09968-1
Autor:
Patryk Ludzia, Christina Redfield, Gabriele Marcianò, Bungo Akiyoshi, Shabaz Mohammed, Edward D. Lowe
Publikováno v:
Structure(London, England:1993)
Summary The kinetochore is the macromolecular machinery that drives chromosome segregation by interacting with spindle microtubules. Kinetoplastids (such as Trypanosoma brucei), a group of evolutionarily divergent eukaryotes, have a unique set of kin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9758ea8e8b17845fb332766f31b920
https://doi.org/10.1101/2020.10.14.337170
https://doi.org/10.1101/2020.10.14.337170
Autor:
Bungo Akiyoshi, Patryk Ludzia
Publikováno v:
Nature Reviews Microbiology. 19:746-746
This month’s Under the Lens discusses how recent advances in understanding the spatial integration of transcription and splicing sites have shed light on the mechanism that ensures monogenic antigen expression in trypanosomes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17132393becf9756ffdc1f0ce98638c3
https://doi.org/10.1038/s41579-021-00641-5
https://doi.org/10.1038/s41579-021-00641-5
Publikováno v:
Open Biology, Vol 9, Iss 12 (2019)
Open Biology
Open Biology
The kinetochore is a multi-protein complex that drives chromosome segregation in eukaryotes. It assembles onto centromere DNA and interacts with spindle microtubules during mitosis and meiosis. Although most eukaryotes have canonical kinetochore prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75bb02089fb4d3ce416a70dd60898851
https://doi.org/10.1098/rsob.190236
https://doi.org/10.1098/rsob.190236
Autor:
Aida, Llauró, Hanako, Hayashi, Megan E, Bailey, Alex, Wilson, Patryk, Ludzia, Charles L, Asbury, Bungo, Akiyoshi
Publikováno v:
The Journal of Cell Biology
The evolutionarily divergent class of kinetoplastid organisms has a set of unconventional kinetochore proteins that drive chromosome segregation, but it is unclear which components interact with spindle microtubules. Llauró et al. now identify KKT4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::400cfc99c3a8d1c2445f380e2bf45076
https://pubmed.ncbi.nlm.nih.gov/30209069
https://pubmed.ncbi.nlm.nih.gov/30209069
Autor:
Megan E. Bailey, Patryk Ludzia, Hanako Hayashi, Bungo Akiyoshi, Charles L. Asbury, Alexander C. Wilson, Aida Llauró
Kinetochores are multiprotein machines that drive chromosome segregation in all eukaryotes by maintaining persistent, load-bearing linkages between the chromosomes and the tips of dynamic spindle microtubules. Kinetochores in commonly studied eukaryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ee465a475f7e786d24eb90506895d1