Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Patrycja Mlotkowska"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Relatively low levels of antioxidant enzymes coupled with high oxygen metabolism result in the formation of numerous oxidative DNA damages in the tissues of the central nervous system. Recently, kynurenic acid (KYNA), knowns for its neuropro
Externí odkaz:
https://doaj.org/article/ae9cd96413e2455c9c72c28131c31a6f
Autor:
Tomasz Misztal, Katarzyna Roszkowicz-Ostrowska, Paweł Kowalczyk, Patrycja Młotkowska, Elżbieta Marciniak
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9428 (2024)
Kynurenic acid (KYNA), a tryptophan metabolite, is believed to exert neuromodulatory and neuroprotective effects in the brain. This study aimed to examine KYNA’s capacity to modify gene expression and the activity of cellular antioxidant enzymes in
Externí odkaz:
https://doaj.org/article/2b8c76d66f5c4a82ade7e3d46cc2fb66
Publikováno v:
Animals, Vol 13, Iss 10, p 1658 (2023)
Oxytocin (OT) is a neuropeptide synthesized in the hypothalamic nuclei that modulates both behavioral and reproductive functions, associated with the increased neurosteroid synthesis in the brain. Therefore, the present study tested the hypothesis th
Externí odkaz:
https://doaj.org/article/ab0770749cac4938b752aa84f7b49aef
Autor:
Katarzyna Roszkowicz-Ostrowska, Patrycja Młotkowska, Paweł Kowalczyk, Elżbieta Marciniak, Marcin Barszcz, Tomasz Misztal
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 136 (2022)
Deficiency of neurotrophic factors and oxidative DNA damage are common causes of many neurodegenerative diseases. Recently, the importance of kynurenic acid (KYNA), an active metabolite of tryptophan, has increased as a neuroprotective molecule in th
Externí odkaz:
https://doaj.org/article/56c404f2015541b0931844f359dacc3f
Autor:
Mariusz T. Skowronski, Patrycja Mlotkowska, Damian Tanski, Ewa Lepiarczyk, Bartosz Kempisty, Lukasz Jaskiewicz, Chandra S. Pareek, Agnieszka Skowronska
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4914 (2019)
This study aimed to examine the effect of follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), and growth hormone (GH) on Aquaporin 5 (AQP5) expression in granulosa (Gc) and theca cells (Tc) from medium (MF) and large (LF) o
Externí odkaz:
https://doaj.org/article/2794deecfa3f42feb87a7782cdea7cb5
Autor:
Mariusz T. Skowronski, Patrycja Mlotkowska, Damian Tanski, Ewa Lepiarczyk, Michal K. Oklinski, Soren Nielsen, Agnieszka Skowronska
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 1, p 5 (2017)
The present in vitro study analyzed whether the hormones that affect the ovarian follicular steroidogenesis process also participate in the regulation of AQP1 mRNA and protein expression. Granulosa (Gc) and theca cells (Tc) of medium and large porcin
Externí odkaz:
https://doaj.org/article/ed2ff7d01d2a49d6a0c77d989c28e9af
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7762 (2020)
The neurosteroid allopregnanolone (AL) has many beneficial functions in the brain. This study tested the hypothesis that AL administered for three days into the third brain ventricle would affect the enzymatic activity of the DNA base excision repair
Externí odkaz:
https://doaj.org/article/b5e67302f1b84cbea274687dc2b82083