Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Patrycja Kozik"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Pore-forming proteins (PFPs) are present in all domains of life, and play an important role in host-pathogen warfare and in the elimination of cancers. They can be employed to deliver specific effectors across membranes, to disrupt membrane integrity
Externí odkaz:
https://doaj.org/article/1eac56f69ff84015ad67f532e3fba77e
Autor:
Patrycja Kozik, Marine Gros, Daniel N. Itzhak, Leonel Joannas, Sandrine Heurtebise-Chrétien, Patrycja A. Krawczyk, Pablo Rodríguez-Silvestre, Andrés Alloatti, Joao Gamelas Magalhaes, Elaine Del Nery, Georg H.H. Borner, Sebastian Amigorena
Publikováno v:
Cell Reports, Vol 32, Iss 2, Pp 107905- (2020)
Summary: Cross-presentation of antigens by dendritic cells (DCs) is critical for initiation of anti-tumor immune responses. Yet, key steps involved in trafficking of antigens taken up by DCs remain incompletely understood. Here, we screen 700 US Food
Externí odkaz:
https://doaj.org/article/f41e73c206eb498a84df86376d83caea
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140404 (2015)
The HIV-1-encoded protein, Nef, plays a key role in the development of AIDS. One of Nef's functions is to keep MHC class I off the surface of infected cells, a process that requires the host proteins clathrin and AP-1. To identify other proteins invo
Externí odkaz:
https://doaj.org/article/6ebf917988bb40e6acd46580d2b0f75b
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64514 (2013)
CALM (clathrin assembly lymphoid myeloid leukemia protein) is a cargo-selective adaptor for the post-Golgi R-SNAREs VAMPs 2, 3, and 8, and it also regulates the size of clathrin-coated pits and vesicles at the plasma membrane. The present study has t
Externí odkaz:
https://doaj.org/article/d665fb411bb54c798fd74d877ea4649f
Autor:
Aydan C. H. Szeto, Ana C. F. Ferreira, Jonathan Mannion, Paula A. Clark, Meera Sivasubramaniam, Morgan W. D. Heycock, Alastair Crisp, Helen E. Jolin, Patrycja Kozik, Martin D. Knolle, Andrew N. J. McKenzie
Publikováno v:
Nature Immunology. 24:123-135
Naive CD4+ T lymphocytes initially undergo antigen-specific activation to promote a broad-spectrum response before adopting bespoke cytokine expression profiles shaped by intercellular microenvironmental cues, resulting in pathogen-focused modular cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ca346888af10ae90e6e3c4740b1495
https://doi.org/10.1038/s41590-022-01378-w
https://doi.org/10.1038/s41590-022-01378-w
Autor:
Pablo Rodríguez-Silvestre, Marco Laub, Alexandra K. Davies, Julia P. Schessner, Patrycja A. Krawczyk, Benjamin J. Tuck, William A. McEwan, Georg H.H. Borner, Patrycja Kozik
During initiation of antiviral and antitumour T cell-mediated immune responses, dendritic cells (DCs) cross-present exogenous antigens on MHC class I. Cross-presentation relies on the unique ‘leakiness’ of endocytic compartments in DCs, whereby i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ec99295124f93af5d707091d954a2d7
https://doi.org/10.1101/2023.01.31.525875
https://doi.org/10.1101/2023.01.31.525875
Publikováno v:
Trends in molecular medicine. 28(4)
Recently, Bikorimana et al. presented a new vaccine formulation, Accum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2037e90f22f6b14d88958e0bbd687b4a
https://pubmed.ncbi.nlm.nih.gov/35288004
https://pubmed.ncbi.nlm.nih.gov/35288004
Autor:
Marine Gros, Elodie Segura, Derek C. Rookhuizen, Blandine Baudon, Sandrine Heurtebise-Chrétien, Nina Burgdorf, Mathieu Maurin, Eugene A. Kapp, Richard J. Simpson, Patrycja Kozik, Jose A. Villadangos, Mathieu J.M. Bertrand, Marianne Burbage, Sebastian Amigorena
Publikováno v:
Cell Reports
Cell Reports, 2022, 40 (7), pp.111205. ⟨10.1016/j.celrep.2022.111205⟩
CELL REPORTS
Cell Reports, 2022, 40 (7), pp.111205. ⟨10.1016/j.celrep.2022.111205⟩
CELL REPORTS
International audience; Despite its crucial role in initiation of cytotoxic immune responses, the molecular pathways underlying antigen cross-presentation remain incompletely understood. The mechanism of antigen exit from endocytic compartments into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f6dae263c114b5590c8084942422e6
https://cnrs.hal.science/hal-03877482
https://cnrs.hal.science/hal-03877482
Publikováno v:
Molecular Immunology. 150:9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a5b6b887fef2aa9a13bb40253155c91
https://doi.org/10.1016/j.molimm.2022.05.039
https://doi.org/10.1016/j.molimm.2022.05.039
Autor:
Ashutosh Trehan, Patrycja Kozik
Publikováno v:
Molecular Immunology. 150:16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8818c3fbd805cd75c2b60bb82c591fe4
https://doi.org/10.1016/j.molimm.2022.05.059
https://doi.org/10.1016/j.molimm.2022.05.059