Zobrazeno 1 - 10 of 71 pro vyhledávání: '"Patrizia Stoppelli"'
1
Akademický článek
MCT4-driven CAF-mediated metabolic reprogramming in breast cancer microenvironment is a vulnerability targetable by miR-425-5p
Autor: Alessandra Affinito, Cristina Quintavalle, Rosario Vincenzo Chianese, Giuseppina Roscigno, Danilo Fiore, Valeria D’Argenio, Guglielmo Thomas, Alessia Savarese, Francesco Ingenito, Lorenza Cocca, Silvia Nuzzo, Maxim V. Berezovski, Maria Patrizia Stoppelli, Gerolama Condorelli
Publikováno v: Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Multiple oncogenic alterations contribute to breast cancer development. Metabolic reprogramming, deeply contributing to tumor microenvironment (TME) education, is now widely recognized as a hallmark of cancer. The reverse Warburg effect indu
Externí odkaz: https://doaj.org/article/2fc61d0e6b1746779017c255a315c01d
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2
Akademický článek
miR-204 targeting of Ankrd13A controls both mesenchymal neural crest and lens cell migration.
Autor: Raffaella Avellino, Sabrina Carrella, Marinella Pirozzi, Maurizio Risolino, Francesco Giuseppe Salierno, Paola Franco, Patrizia Stoppelli, Pasquale Verde, Sandro Banfi, Ivan Conte
Publikováno v: PLoS ONE, Vol 8, Iss 4, p e61099 (2013)
Loss of cell adhesion and enhancement of cell motility contribute to epithelial-to-mesenchymal transition during development. These processes are related to a) rearrangement of cell-cell and cell-substrate adhesion molecules; b) cross talk between ex
Externí odkaz: https://doaj.org/article/28194eb1f3ce4c5bb1367431d9a702e6
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3
Akademický článek
Exosomal microRNAs synergistically trigger stromal fibroblasts in breast cancer
Autor: Iolanda Scognamiglio, Lorenza Cocca, Ilaria Puoti, Francesco Palma, Francesco Ingenito, Cristina Quintavalle, Alessandra Affinito, Giuseppina Roscigno, Silvia Nuzzo, Rosario Vincenzo Chianese, Stefania Belli, Guglielmo Thomas, Timo Schomann, Alan Chan, Maria Patrizia Stoppelli, Gerolama Condorelli
Publikováno v: Molecular Therapy: Nucleic Acids, Vol 28, Iss , Pp 17-31 (2022)
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype. TNBC progression is sustained by recruitment of a strong tumor microenvironment (TME) mainly composed of cancer-associated fibroblasts (CAFs) able to endorse tumor hal
Externí odkaz: https://doaj.org/article/26bca4025edc49b0acd8b1782fa15af9
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4
Akademický článek
Modulation of Cellular Function by the Urokinase Receptor Signalling: A Mechanistic View
Autor: Daniela Alfano, Paola Franco, Maria Patrizia Stoppelli
Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Urokinase-type plasminogen activator receptor (uPAR or CD87) is a glycosyl-phosphatidyl-inositol anchored (GPI) membrane protein. The uPAR primary ligand is the serine protease urokinase (uPA), converting plasminogen into plasmin, a broad spectrum pr
Externí odkaz: https://doaj.org/article/3e9ae378f3f64a3f8eac86cc92ed4834
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5
Akademický článek
Targeting the cross-talk between Urokinase receptor and Formyl peptide receptor type 1 to prevent invasion and trans-endothelial migration of melanoma cells
Autor: Concetta Ragone, Michele Minopoli, Vincenzo Ingangi, Giovanni Botti, Federica Fratangelo, Antonello Pessi, Maria Patrizia Stoppelli, Paolo Antonio Ascierto, Gennaro Ciliberto, Maria Letizia Motti, Maria Vincenza Carriero
Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-16 (2017)
Abstract Background Accumulating evidence demonstrates that the Urokinase Receptor (uPAR) regulates tumor cell migration through its assembly in composite regulatory units with transmembrane receptors, and uPAR88–92 is the minimal sequence required
Externí odkaz: https://doaj.org/article/3f3287fd62da493eaa830b099a0bd4e9
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7
Data from A Urokinase Receptor–Derived Peptide Inhibiting VEGF-Dependent Directional Migration and Vascular Sprouting
Autor: Maria Vincenza Carriero, Maria Patrizia Stoppelli, Vincenzo Pavone, Mario De Rosa, Maria Teresa Masucci, Domenica Rea, Claudio Arra, Eleonora Liguori, Immacolata Longanesi-Cattani, Katia Bifulco
The receptor for the urokinase-type plasminogen activator (uPAR) is a widely recognized master regulator of cell migration, and uPAR88–92 is the minimal sequence required to induce cell motility. We previously showed that soluble forms of uPAR elic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c4d6ac53c36d8f5f40abd68545682b16
https://doi.org/10.1158/1535-7163.c.6536100
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