Zobrazeno 1 - 10
of 190
pro vyhledávání: '"Patrizia Sabatelli"'
Autor:
Manuela Moriggi, Enrica Torretta, Matilde Cescon, Loris Russo, Ilaria Gregorio, Paola Braghetta, Patrizia Sabatelli, Cesare Faldini, Luciano Merlini, Cesare Gargioli, Paolo Bonaldo, Cecilia Gelfi, Daniele Capitanio
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7118 (2024)
Pericytes are a distinct type of cells interacting with endothelial cells in blood vessels and contributing to endothelial barrier integrity. Furthermore, pericytes show mesenchymal stem cell properties. Muscle-derived pericytes can demonstrate both
Externí odkaz:
https://doaj.org/article/4214af8259e44f6fa471124b64b1c968
Autor:
Nastasia Cardone, Melissa Moula, Rianne J. Baelde, Ariane Biquand, Marcello Villanova, Corinne Metay, Chiara Fiorillo, Serena Baratto, Luciano Merlini, Patrizia Sabatelli, Norma B. Romero, Frederic Relaix, François Jérôme Authier, Valentina Taglietti, Marco Savarese, Josine de Winter, Coen Ottenheijm, Isabelle Richard, Edoardo Malfatti
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-10 (2023)
Abstract Congenital titinopathies are an emerging group of a potentially severe form of congenital myopathies caused by biallelic mutations in titin, encoding the largest existing human protein involved in the formation and stability of sarcomeres. I
Externí odkaz:
https://doaj.org/article/5fea3216d6b44beab3e6bcbaf02277ca
Autor:
Vittoria Cenni, Patrizia Sabatelli, Alberto Di Martino, Luciano Merlini, Manuela Antoniel, Stefano Squarzoni, Simona Neri, Spartaco Santi, Samuele Metti, Paolo Bonaldo, Cesare Faldini
Publikováno v:
Cells, Vol 13, Iss 5, p 378 (2024)
The pericellular matrix (PCM) is a specialized extracellular matrix that surrounds cells. Interactions with the PCM enable the cells to sense and respond to mechanical signals, triggering a proper adaptive response. Collagen VI is a component of musc
Externí odkaz:
https://doaj.org/article/c453625c018140808afd9f71a0119467
Autor:
Lisa Gambarotto, Samuele Metti, Martina Chrisam, Cristina Cerqua, Patrizia Sabatelli, Andrea Armani, Carlo Zanon, Marianna Spizzotin, Silvia Castagnaro, Flavie Strappazzon, Paolo Grumati, Matilde Cescon, Paola Braghetta, Eva Trevisson, Francesco Cecconi, Paolo Bonaldo
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 4, Pp 2211-2224 (2022)
Abstract Background Maintaining healthy mitochondria is mandatory for muscle viability and function. An essential surveillance mechanism targeting defective and harmful mitochondria to degradation is the selective form of autophagy called mitophagy.
Externí odkaz:
https://doaj.org/article/20e28c3148de45fc84c282fe3f3670ae
Autor:
Vittoria Cenni, Camilla Evangelisti, Spartaco Santi, Patrizia Sabatelli, Simona Neri, Marco Cavallo, Giovanna Lattanzi, Elisabetta Mattioli
Publikováno v:
Cells, Vol 13, Iss 2, p 162 (2024)
In muscle cells subjected to mechanical stimulation, LINC complex and cytoskeletal proteins are basic to preserve cellular architecture and maintain nuclei orientation and positioning. In this context, the role of lamin A/C remains mostly elusive. Th
Externí odkaz:
https://doaj.org/article/d01b1c0d03794a5eba64ac7101dbe90c
Autor:
Camilla M. Fontana, Lisa Locatello, Patrizia Sabatelli, Nicola Facchinello, Elisa Lidron, Francesca Maradonna, Oliana Carnevali, Maria B. Rasotto, Luisa Dalla Valle
Publikováno v:
Biomedical Journal, Vol 45, Iss 2, Pp 377-386 (2022)
Background: Dysregulation of the autophagic flux is linked to a wide array of human diseases, and recent findings highlighted the central role of autophagy in reproduction, as well as an association between impairment of autophagy and behavioural dis
Externí odkaz:
https://doaj.org/article/73a7f944b0fe46c8ae0b8ddf0a988753
Autor:
Luciano Merlini, Patrizia Sabatelli, Francesca Gualandi, Edoardo Redivo, Alberto Di Martino, Cesare Faldini
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12474 (2023)
Pathogenetic mechanism recognition and proof-of-concept clinical trials were performed in our patients affected by collagen VI-related myopathies. This study, which included 69 patients, aimed to identify innovative clinical data to better design fut
Externí odkaz:
https://doaj.org/article/fb741869de0f472a8b2f910a133baec6
Autor:
Michela Starace, Francesca Pampaloni, Francesca Bruni, Federico Quadrelli, Stephano Cedirian, Carlotta Baraldi, Cosimo Misciali, Alberto Di Martino, Patrizia Sabatelli, Luciano Merlini, Bianca Maria Piraccini
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6678 (2023)
Collagen VI-related myopathies are characterized by severe muscle involvement and skin involvement (keratosis pilaris and impaired healing with the development of abnormal scars, especially keloids). Scalp involvement and hair loss have not been repo
Externí odkaz:
https://doaj.org/article/27ae1571b7c44e909aa584a447307244
Autor:
Alberto Di Martino, Matilde Cescon, Claudio D’Agostino, Francesco Schilardi, Patrizia Sabatelli, Luciano Merlini, Cesare Faldini
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5095 (2023)
Collagen VI exerts several functions in the tissues in which it is expressed, including mechanical roles, cytoprotective functions with the inhibition of apoptosis and oxidative damage, and the promotion of tumor growth and progression by the regulat
Externí odkaz:
https://doaj.org/article/e4c6bc1030344b978a6f17798b48c66e
Autor:
Maria Sofia Falzarano, Rachele Rossi, Andrea Grilli, Mingyan Fang, Hana Osman, Patrizia Sabatelli, Manuela Antoniel, Zhiyuan Lu, Wenyan Li, Rita Selvatici, Cristina Al-Khalili, Francesca Gualandi, Silvio Bicciato, Silvia Torelli, Alessandra Ferlini
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Background: Neuromuscular disorders (NMDs) are a heterogeneous group of genetic diseases, caused by mutations in genes involved in spinal cord, peripheral nerve, neuromuscular junction, and muscle functions. To advance the knowledge of the pathologic
Externí odkaz:
https://doaj.org/article/73150439769649459f63a62da9f5f2a9