Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Patrizia Panzanelli"'
Autor:
Yuan-Chen Tsai, Mohammad Hleihil, Kanako Otomo, Andrin Abegg, Anna Cavaccini, Patrizia Panzanelli, Teresa Cramer, Kim David Ferrari, Matthew J. P. Barrett, Giovanna Bosshard, Theofanis Karayannis, Bruno Weber, Shiva K. Tyagarajan, Jillian L. Stobart
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Gephyrin is the main scaffolding protein at inhibitory postsynaptic sites, and its clusters are the signaling hubs where several molecular pathways converge. Post-translational modifications (PTMs) of gephyrin alter GABAA receptor clustering
Externí odkaz:
https://doaj.org/article/61f06bd1f1de40d1b7c391b161388674
Autor:
Teresa M.L. Cramer, Berangere Pinan-Lucarre, Anna Cavaccini, Angeliki Damilou, Yuan-Chen Tsai, Musadiq A. Bhat, Patrizia Panzanelli, Nicolas Rama, Patrick Mehlen, Dietmar Benke, Theofanis Karayannis, Jean-Louis Bessereau, Shiva K. Tyagarajan
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112947- (2023)
Summary: The molecular code that controls synapse formation and maintenance in vivo has remained quite sparse. Here, we identify that the secreted protein Adamtsl3 functions as critical hippocampal synapse organizer acting through the transmembrane r
Externí odkaz:
https://doaj.org/article/5d6008f4088e4776b7758e3496236210
Autor:
Federica Foglietta, Roberto Canaparo, Simone Cossari, Patrizia Panzanelli, Franco Dosio, Loredana Serpe
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1102 (2022)
The use of ultrasound (US) in combination with a responsive chemical agent (sonosensitizer) can selectively trigger the agent’s anticancer activity in a process called sonodynamic therapy (SDT). SDT shares some properties with photodynamic therapy
Externí odkaz:
https://doaj.org/article/9c1a9243f4834483b45ad780bad5ec1c
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 615 (2022)
Sonodynamic therapy (SDT) is a noninvasive method for cancer treatment based on selective activation of a sonosensitiser by ultrasound (US), which results in the generation of reactive oxygen species (ROS) and cancer cell death. SDT uses a similar ap
Externí odkaz:
https://doaj.org/article/3166c47a8cc14817be7210406b5c7688
Autor:
Federica Foglietta, Manuela Macrì, Patrizia Panzanelli, Andrea Francovich, Gianni Durando, Francesca Garello, Enzo Terreno, Loredana Serpe, Roberto Canaparo
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 183:119-131
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a290bf95d0f6edb1b688a0b2c9cb2aaf
https://doi.org/10.1016/j.ejpb.2023.01.005
https://doi.org/10.1016/j.ejpb.2023.01.005
Autor:
Rochelle M. Hines, Hans Michael Maric, Dustin J. Hines, Amit Modgil, Patrizia Panzanelli, Yasuko Nakamura, Anna J. Nathanson, Alan Cross, Tarek Deeb, Nicholas J. Brandon, Paul Davies, Jean-Marc Fritschy, Hermann Schindelin, Stephen J. Moss
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
The inhibitory synaptic protein collybistin (CB) and GABAAR-α subunits are thought to interact, but strength and specificity are unclear. Here the authors study the CB–α2 interaction and show that a mouse mutated in the CB-binding region of α2 d
Externí odkaz:
https://doaj.org/article/603d64a78c594cd6a9206450bd9f2e4e
Autor:
Vanessa Pinnelli, Loredana Serpe, Roberto Canaparo, Patrizia Panzanelli, Gianni Durando, Francesca Giuntini, Nadia Barbero, Federica Foglietta, Enzo Terreno
Publikováno v:
Cancers
Cancers, Vol 13, Iss 3852, p 3852 (2021)
Volume 13
Issue 15
Cancers, Vol 13, Iss 3852, p 3852 (2021)
Volume 13
Issue 15
Sonodynamic Therapy (SDT) is a new anticancer strategy based on ultrasound (US) technique and is derived from photodynamic therapy (PDT)
SDT is still, however, far from clinical application. In order to move this therapy forward from bench to be
SDT is still, however, far from clinical application. In order to move this therapy forward from bench to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a350623c62c96d1cded167653add633
https://hdl.handle.net/2318/1801733
https://hdl.handle.net/2318/1801733
Autor:
Yuan-Chen Tsai, Mohammad Hleihil, Kanako Otomo, Andrin Abegg, Anna Cavaccini, Patrizia Panzanelli, Teresa Cramer, Kim David Ferrari, Matthew J.P. Barrett, Giovanna Bosshard, Theofanis Karayannis, Bruno Weber, Jillian L. Stobart, Shiva K. Tyagarajan
A diverse set of GABAA receptors (GABAARs) enable synaptic plasticity adaptations at inhibitory postsynaptic sites in collaboration with the scaffolding protein gephyrin. Early studies helped to identify distinctions between GABAAR subtypes allocated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7fd2aff0c65ae3671aacdabde34ecc4
https://doi.org/10.1101/2020.11.25.397877
https://doi.org/10.1101/2020.11.25.397877
Autor:
Alessandro Ciccarelli, Arianna Calza, Patrizia Panzanelli, Alessandra Concas, Maurizio Giustetto, Marco Sassoè-Pognetto
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46250 (2012)
The ventral tegmental area (VTA) is widely implicated in drug addiction and other psychiatric disorders. This brain region is densely populated by dopaminergic (DA) neurons and also contains a sparse population of γ-aminobutyric acid (GABA)ergic cel
Externí odkaz:
https://doaj.org/article/ea235f5c1f6d469cbbcc897ee281be93
Autor:
Simon Früh, Mirko Santello, Jennifer Romanos, Shiva K. Tyagarajan, Patrizia Panzanelli, Daniela Bürgisser, Kevin P. Campbell, Jean-Marc Fritschy
Publikováno v:
Journal of Neuroscience
Distinct types of GABAergic interneurons target different subcellular domains of pyramidal cells, thereby shaping pyramidal cell activity patterns. Whether the presynaptic heterogeneity of GABAergic innervation is mirrored by specific postsynaptic fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd73767018ed86f8485d16c2b0676561
https://doi.org/10.1523/jneurosci.1823-16.2016
https://doi.org/10.1523/jneurosci.1823-16.2016