Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Patrizia Giannoni"'
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 285, Iss , Pp 117045- (2024)
The increasing concern over the environmental presence of β-N-Methylamino-L-alanine (BMAA), a toxin primarily produced by cyanobacteria and diatoms, has stimulated numerous studies to evaluate the risk for exposed populations, mainly aquatic organis
Externí odkaz:
https://doaj.org/article/68f701126d9c42db86dd7772ecb31c91
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Externí odkaz:
https://doaj.org/article/13ac4cdb6c4c4c2b831818add90a0d7d
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Externí odkaz:
https://doaj.org/article/2e531efcc21c4844b531c3f919844255
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
A bidirectional crosstalk between peripheral players of immunity and the central nervous system (CNS) exists. Hence, blood–brain barrier (BBB) breakdown is emerging as a participant mechanism of dysregulated peripheral–CNS interplay, promoting di
Externí odkaz:
https://doaj.org/article/3ed79f1e33a64699ba3b7bae1ec12434
Autor:
Patrizia Giannoni, Margarita Arango-Lievano, Ines Das Neves, Marie-Claude Rousset, Kévin Baranger, Santiago Rivera, Freddy Jeanneteau, Sylvie Claeysen, Nicola Marchi
Publikováno v:
Neurobiology of Disease, Vol 88, Iss , Pp 107-117 (2016)
Clinical and experimental evidence point to a possible role of cerebrovascular dysfunction in Alzheimer's disease (AD). The 5xFAD mouse model of AD expresses human amyloid precursor protein and presenilin genes with mutations found in AD patients. It
Externí odkaz:
https://doaj.org/article/f6422509dc544197b16d363dae4632e6
Autor:
Silvia Fossati, Patrizia Giannoni, Maria E. Solesio, Sarah L. Cocklin, Erwin Cabrera, Jorge Ghiso, Agueda Rostagno
Publikováno v:
Neurobiology of Disease, Vol 86, Iss , Pp 29-40 (2016)
Mitochondrial dysfunction has been recognized as an early event in Alzheimer's disease (AD) pathology, preceding and inducing neurodegeneration and memory loss. The presence of cytochrome c (CytC) released from the mitochondria into the cytoplasm is
Externí odkaz:
https://doaj.org/article/165bbc7be0b74a2fb820d193492ef648
Autor:
Farron Lynn McIntee, Patrizia Giannoni, Steven Blais, George Sommer, Thomas Neubert, Agueda Rostagno, Jorge Ghiso
Publikováno v:
Frontiers in Aging Neuroscience, Vol 8 (2016)
Amyloid β (Aβ) is the major constituent of the brain deposits found in parenchymal plaques and cerebral blood vessels of patients with Alzheimer’s disease (AD). Several lines of investigation support the notion that synaptic pathology, one of the
Externí odkaz:
https://doaj.org/article/c60c3f1ce55d4de2884899e386994296
Publikováno v:
Life Sciences. 304:120689
Brain disease, in its many forms, has recently demonstrated a great socio-economic impact and represents one of the hardest challenges of present research. Although each pathology of this highly heterogenous group is characterized by individual featu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922c5fa1577fb426aed8b9f8ddac084e
https://doi.org/10.1016/j.lfs.2022.120689
https://doi.org/10.1016/j.lfs.2022.120689
Publikováno v:
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience, Frontiers, 2020, 1, ⟨10.3389/fnagi.2020.00169⟩
Frontiers in Aging Neuroscience, Vol 12 (2020)
Frontiers in Aging Neuroscience, Frontiers, 2020, 1, ⟨10.3389/fnagi.2020.00169⟩
Frontiers in Aging Neuroscience, Vol 12 (2020)
International audience; This Research Topic is a collection of 20 articles that depict a broad representation of the most impactful advances in Alzheimer’s disease (AD) comprehension and therapeutic openings. As it clearly emerges from recent liter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc5679cf407a3bd8ebfdb2ee0bc442a
https://doi.org/10.3389/fnagi.2020.00169
https://doi.org/10.3389/fnagi.2020.00169
Autor:
Kévin Baranger, Patrick Dallemagne, Thomas Freret, Joël Bockaert, Eleazere Cem, Serge Mignani, Michel Boulouard, Katia Hamidouche, Sylvie Claeysen, Patrizia Giannoni, Christophe Rochais, Cédric Lecoutey, Santiago Rivera, Florence Gaven
Publikováno v:
Br J Pharmacol
BACKGROUND AND PURPOSE: We recently identified donecopride as a pleiotropic compound able to inhibit acetylcholinesterase and to activate serotonin subtype 4 receptor. The purpose of the present article is to establish its potential therapeutic inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a245a96ad516379a48e563955d4f648b
https://europepmc.org/articles/PMC7161555/
https://europepmc.org/articles/PMC7161555/
