Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Patrizia Costi"'
Autor:
Fabio A. Zucca, Weslyn C. Ward, Patrizia Costi, John D. Simon, Chiara Bellei, Mario Gallorini, Luigi Zecca, Alberto Moscatelli, Kazumasa Wakamatsu, Melvin Eisner, William D. Bush, Pier Raimondo Crippa, Luigi Bergamaschi, Shosuke Ito, Luigi Casella, Enrico Monzani, Alberto Albertini, Nicholas J. Turro
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 105 (2008): 17567–17572. doi:10.1073/pnas.0808768105
info:cnr-pdr/source/autori:Zecca L.; Bellei C.; Costi P.; Albertini A.; Monzani E.; Casella L.; Gallorini M.; Bergamaschi L.; Moscatelli A.; Turro N.J.; Eisner M.; Crippa P.R.; Ito S.; Wakamatsu K.; Bush W.D.; Ward W.C.; Simon J.D.; Zucca F.A./titolo:New melanic pigments in the human brain that accumulate in aging and block environmental toxic metals/doi:10.1073%2Fpnas.0808768105/rivista:Proceedings of the National Academy of Sciences of the United States of America/anno:2008/pagina_da:17567/pagina_a:17572/intervallo_pagine:17567–17572/volume:105
info:cnr-pdr/source/autori:Zecca L.; Bellei C.; Costi P.; Albertini A.; Monzani E.; Casella L.; Gallorini M.; Bergamaschi L.; Moscatelli A.; Turro N.J.; Eisner M.; Crippa P.R.; Ito S.; Wakamatsu K.; Bush W.D.; Ward W.C.; Simon J.D.; Zucca F.A./titolo:New melanic pigments in the human brain that accumulate in aging and block environmental toxic metals/doi:10.1073%2Fpnas.0808768105/rivista:Proceedings of the National Academy of Sciences of the United States of America/anno:2008/pagina_da:17567/pagina_a:17572/intervallo_pagine:17567–17572/volume:105
Neuronal pigments of melanic type were identified in the putamen, cortex, cerebellum, and other major regions of human brain. These pigments consist of granules 30 nm in size, contained in organelles together with lipid droplets, and they accumulate
Autor:
Shosuke Ito, Christian Griesinger, Kay L. Double, Gerhard Bringmann, Patrizia Costi, M Mauer, Peter Riederer, Manfred Gerlach, Dorit Ben-Shachar, Luigi Zecca, Ruggero Fariello
Publikováno v:
Journal of Neurochemistry
Neuromelanin (NM) is a complex polymer pigment found primarily in the dopaminergic neurons of the human substantia nigra. The structure of NM is only partially characterized, and its synthesis pathway remains unknown. We used nuclear magnetic and inf
Publikováno v:
Journal of Neurochemistry. 74:1758-1765
Neuromelanin was isolated from human substantia nigra using different procedures. In the pigment isolated by any of these procedures a peptide component covalently bound to the melanic structure was found, as shown by treatment with reagents known to
Publikováno v:
Pharmacology Biochemistry and Behavior. 51:29-35
Bilateral electrolytic lesions of the red nucleus (RN) of rat decreased apomorphine-induced stereotypy, increased haloperidol-induced catalepsy, reversed apomorphine-induced hypothermy, decreased spiroperidol-induced hypomotility, and BHT-920-induced
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 567:425-432
A reversed-phase high-performance liquid chromatographic method with electrochemical detection for the quantitation of diclofenac and metabolites in plasma and cerebrospinal fluid has been developed. Pirprofen is employed as internal standard. Sample
Autor:
Davide Tampellini, Patrizia Costi, Fabio A. Zucca, David Sulzer, Mario Gallorini, Luigi Zecca, Manfred Gerlach, Ruggero Fariello, Peter Riederer, Alberto Gatti, Shosuke Ito
Publikováno v:
Advances in Research on Neurodegeneration ISBN: 9783211839072
The pigmented neurons of the substantia nigra (SN) are typically lost in Parkinson’s disease: however the possible relationship between neuronal vulnerability and the presence of neuromelanin (NM) has not been elucidated. Early histological studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8abb281f0869faaf7f146d64f190255b
https://doi.org/10.1007/978-3-7091-0643-3_8
https://doi.org/10.1007/978-3-7091-0643-3_8