Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Patrizia Cancemi"'
Autor:
Roberta F. Chiavetta, Simona Titoli, Viviana Barra, Patrizia Cancemi, Raffaella Melfi, Aldo Di Leonardo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10940 (2023)
It is reported that about 10% of cystic fibrosis (CF) patients worldwide have nonsense (stop) mutations in the CFTR gene, which cause the premature termination of CFTR protein synthesis, leading to a truncated and non-functional protein. To address t
Externí odkaz:
https://doaj.org/article/8544a39bfafb4668b718a2e41ba59dab
Autor:
Giuseppe Angellotti, Giulia Di Prima, Fabio D'Agostino, Emanuela Peri, Maria Rita Tricoli, Elena Belfiore, Mario Allegra, Patrizia Cancemi, Viviana De Caro
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8382 (2023)
The well-being of skin and mucous membranes is fundamental for the homeostasis of the body and thus it is imperative to treat any lesion quickly and correctly. In this view, polyphenols might assist and enhance a successful wound healing process by r
Externí odkaz:
https://doaj.org/article/6314d91a7f884642b473247ffd61770b
Autor:
Gabriella Schiera, Patrizia Cancemi, Carlo Maria Di Liegro, Flores Naselli, Sara Volpes, Ilenia Cruciata, Paola Sofia Cardinale, Fabiola Vaglica, Matteo Calligaris, Anna Paola Carreca, Roberto Chiarelli, Simone Dario Scilabra, Olga Leone, Fabio Caradonna, Italia Di Liegro
Publikováno v:
Genes, Vol 14, Iss 5, p 990 (2023)
Gliomas are the prevalent forms of brain cancer and derive from glial cells. Among them, astrocytomas are the most frequent. Astrocytes are fundamental for most brain functions, as they contribute to neuronal metabolism and neurotransmission. When th
Externí odkaz:
https://doaj.org/article/1e57efac8292499cb1362a61985a874e
Autor:
Pasquale Picone, Fabio Salvatore Palumbo, Salvatore Federico, Giovanna Pitarresi, Giorgia Adamo, Antonella Bongiovanni, Antonio Chaves, Patrizia Cancemi, Vera Muccilli, Valentina Giglio, Valeria Vetri, Sara Anselmo, Giuseppe Sancataldo, Valentina Di Liberto, Domenico Nuzzo
Publikováno v:
Materials Today Bio, Vol 12, Iss , Pp 100146- (2021)
Neurodegenerative diseases affect millions of people worldwide and the presence of various physiological barriers limits the accessibility to the brain and reduces the efficacy of various therapies. Moreover, new carriers having targeting properties
Externí odkaz:
https://doaj.org/article/c08570d9f8614a62968d8138353f94a2
Autor:
Valentina Di Felice, Rosario Barone, Eleonora Trovato, Daniela D’Amico, Filippo Macaluso, Claudia Campanella, Antonella Marino Gammazza, Vera Muccilli, Vincenzo Cunsolo, Patrizia Cancemi, Gabriele Multhoff, Dario Coletti, Sergio Adamo, Felicia Farina, Francesco Cappello
Publikováno v:
Cells, Vol 11, Iss 9, p 1406 (2022)
Currently, no commercially available drugs have the ability to reverse cachexia or counteract muscle wasting and the loss of lean mass. Here, we report the methodology used to develop Physiactisome—a conditioned medium released by heat shock protei
Externí odkaz:
https://doaj.org/article/a6fd71659ea948c09164606318511f7e
Autor:
Patrizia Cancemi, Anna Aiello, Giulia Accardi, Rosalia Caldarella, Giuseppina Candore, Calogero Caruso, Marcello Ciaccio, Laura Cristaldi, Francesca Di Gaudio, Valentina Siino, Sonya Vasto
Publikováno v:
Mediators of Inflammation, Vol 2020 (2020)
Extracellular matrix metalloproteinases (MMPs) are a group of proteins that activate substrates by enzymatic cleavage and, on the basis of their activities, have been demonstrated to play a role in ageing. Thus, in order to gain insight into the path
Externí odkaz:
https://doaj.org/article/61c5c1e630b84c5492f8f0d14309bacb
Autor:
Miriam Buttacavoli, Gianluca Di Cara, Elena Roz, Ida Pucci-Minafra, Salvatore Feo, Patrizia Cancemi
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12389 (2021)
Colorectal cancer (CRC) develops by genetic and epigenetic alterations. However, the molecular mechanisms underlying metastatic dissemination remain unclear and could benefit from multi-omics investigations of specific protein families. Matrix metall
Externí odkaz:
https://doaj.org/article/fbdbf667fff548afb0643e9ff5307b0b
Autor:
Ilaria Caon, Maria Luisa D’Angelo, Barbara Bartolini, Elena Caravà, Arianna Parnigoni, Flavia Contino, Patrizia Cancemi, Paola Moretto, Nikos K. Karamanos, Alberto Passi, Davide Vigetti, Evgenia Karousou, Manuela Viola
Publikováno v:
Cancers, Vol 13, Iss 5, p 1105 (2021)
Interaction between cancer cells and their microenvironment is central in defining the fate of cancer development. Tumour cells secrete signals (cytokines, chemokines, growth factors) that modify the surrounding area, while the niche supplies structu
Externí odkaz:
https://doaj.org/article/006b372428064fda9412bb8410bb8598
Autor:
Miriam Buttacavoli, Gianluca Di Cara, Cesare D’Amico, Fabiana Geraci, Ida Pucci-Minafra, Salvatore Feo, Patrizia Cancemi
Publikováno v:
Biology, Vol 10, Iss 3, p 247 (2021)
Heat shock proteins (HSPs) are a well-characterized molecular chaperones protein family, classified into six major families, according to their molecular size. A wide range of tumors have been shown to express atypical levels of one or more HSPs, sug
Externí odkaz:
https://doaj.org/article/0ea2ea80a5f9419cb782d97bd3631bd7
Publikováno v:
Heliyon, Vol 5, Iss 6, Pp e01963- (2019)
The readthrough of nonsense mutations by small molecules like Ataluren is considered a novel therapeutic approach to overcome the gene defect in several genetic diseases as cystic fibrosis (CF). This pharmacological approach suppresses translation te
Externí odkaz:
https://doaj.org/article/2155e2d78ffc48e1b819bd302e0d337e