Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Patrizia, Porazzi"'
Autor:
Yunlin Zhang, Ruchi P. Patel, Ki Hyun Kim, Hyungwoo Cho, Jae-Cheol Jo, Seong Hyun Jeong, Sung Yong Oh, Yoon Seok Choi, Sung Hyun Kim, Ji Hyun Lee, Mathew Angelos, Puneeth Guruprasad, Ivan Cohen, Ositadimma Ugwuanyi, Yong Gu Lee, Raymone Pajarillo, Jong Hyun Cho, Alberto Carturan, Luca Paruzzo, Guido Ghilardi, Michael Wang, Soohwan Kim, Sung-Min Kim, Hyun-Jong Lee, Ji-Ho Park, Leiguang Cui, Tae Bum Lee, In-Sik Hwang, Young-Ha Lee, Yong-Jun Lee, Patrizia Porazzi, Dongfang Liu, Yoon Lee, Jong-Hoon Kim, Jong-Seo Lee, Dok Hyun Yoon, Junho Chung, Marco Ruella
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-23 (2023)
Abstract Background Commercial anti-CD19 chimeric antigen receptor T-cell therapies (CART19) are efficacious against advanced B-cell non-Hodgkin lymphoma (NHL); however, most patients ultimately relapse. Several mechanisms contribute to this failure,
Externí odkaz:
https://doaj.org/article/f352f6b7f911417286a5dd19eb392756
Autor:
Marco Ruella, Yong Gu Lee, Nicholas Yang, Inkook Chun, Patrizia Porazzi, Alberto Carturan, Luca Paruzzo, Christopher Tor Sauter, Puneeth Guruprasad, Raymone Pajarillo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)
Immunotherapy has revolutionized the treatment of cancer. In particular, immune checkpoint blockade, bispecific antibodies, and adoptive T-cell transfer have yielded unprecedented clinical results in hematological malignancies and solid cancers. Whil
Externí odkaz:
https://doaj.org/article/3234ef3ae87941f2a4475be752f10e55
Autor:
Luca Pagliaroli, Patrizia Porazzi, Alyxandra T. Curtis, Chiara Scopa, Harald M. M. Mikkers, Christian Freund, Lucia Daxinger, Sandra Deliard, Sarah A. Welsh, Sarah Offley, Connor A. Ott, Bruno Calabretta, Samantha A. Brugmann, Gijs W. E. Santen, Marco Trizzino
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Mutations in the ARID1B subunit of the BAF chromatin remodeling complex are associated with the neurodevelopmental Coffin-Siris syndrome. Here the authors reveal that there is a transition from ARID1A-containing complexes to ARID1B during cranial neu
Externí odkaz:
https://doaj.org/article/d81d9aec3d4b4606a4380fcc57816cd2
Autor:
Javad Rasouli, Giacomo Casella, Larissa L. W. Ishikawa, Rodolfo Thome, Alexandra Boehm, Adam Ertel, Carolina R. Melo-Silva, Elisabeth R. Mari, Patrizia Porazzi, Weifeng Zhang, Dan Xiao, Luis J. Sigal, Paolo Fortina, Guang-Xian Zhang, Abdolmohamad Rostami, Bogoljub Ciric
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IFN-β has been the treatment for multiple sclerosis (MS) for almost three decades, but understanding the mechanisms underlying its beneficial effects remains incomplete. We have shown that MS patients have increased numbers of GM-CSF+ Th cells in ci
Externí odkaz:
https://doaj.org/article/5b73622522934dc1a2b4a1b2ed9a906b
Autor:
Svetlana Petruk, Samanta A. Mariani, Marco De Dominici, Patrizia Porazzi, Valentina Minieri, Jingli Cai, Lorraine Iacovitti, Neal Flomenberg, Bruno Calabretta, Alexander Mazo
Publikováno v:
Cell Reports, Vol 19, Iss 2, Pp 295-306 (2017)
Summary: The role of chromatin structure in lineage commitment of multipotent hematopoietic progenitors (HPCs) is presently unclear. We show here that CD34+ HPCs possess a post-replicative chromatin globally devoid of the repressive histone mark H3K2
Externí odkaz:
https://doaj.org/article/5bd388368332412081472e38aff5b32a
Autor:
Guido Ghilardi, Yong Gu Lee, Patrizia Porazzi, Ivan Cohen, Luca Paruzzo, Ositadimma H Ugwuanyi, Raymone Pajarillo, Yunlin Zhang, Puneeth Guruprasad, Ruchi P. Patel, Elise A. Chong, Sunita Dwivedy Nasta, Stefan K. Barta, Alfred L. Garfall, Daniel J. Landsburg, Sam Sadigh, Mariusz Wasik, Jakub Svoboda, Siddharth Bhattacharyya, Stephen J. Schuster, Marco Ruella
Publikováno v:
Blood. 140:7371-7373
Autor:
Marco Ruella, Patrizia Porazzi, Stephen J. Schuster, James Gerson, Sara Cherry, David C. Schultz, Kanupriya Whig, Yunlin Zhang, Xueqing Maggie Lu, Simon F. Lacey, Wan-Jung Chang, Joseph A. Fraietta, Sarah E. Church, Khrystyna North, Elise A. Chong, Saar Gill, Jakub Svoboda, Katherine D. Cummins, Kimberly V. Amelsberg, Nicholas Yang, Inkook Chun, Seok Jae Hong, Hatcher J. Ballard, Ruchi Patel, Christopher Tor Sauter, Raymone Pajarillo, Guido Ghilardi, Puneeth Guruprasad, Yong Gu Lee
Supplementary Figure from Modulation of BCL-2 in Both T Cells and Tumor Cells to Enhance Chimeric Antigen Receptor T-cell Immunotherapy against Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d63f43f4903bc7d8bbd7a04cf8ac881
https://doi.org/10.1158/2159-8290.22541380.v1
https://doi.org/10.1158/2159-8290.22541380.v1
Autor:
Marco Ruella, Patrizia Porazzi, Stephen J. Schuster, James Gerson, Sara Cherry, David C. Schultz, Kanupriya Whig, Yunlin Zhang, Xueqing Maggie Lu, Simon F. Lacey, Wan-Jung Chang, Joseph A. Fraietta, Sarah E. Church, Khrystyna North, Elise A. Chong, Saar Gill, Jakub Svoboda, Katherine D. Cummins, Kimberly V. Amelsberg, Nicholas Yang, Inkook Chun, Seok Jae Hong, Hatcher J. Ballard, Ruchi Patel, Christopher Tor Sauter, Raymone Pajarillo, Guido Ghilardi, Puneeth Guruprasad, Yong Gu Lee
Chimeric antigen receptor T-cell (CART) immunotherapy led to unprecedented responses in patients with refractory/relapsed B-cell non-Hodgkin lymphoma (NHL); nevertheless, two thirds of patients experience treatment failure. Resistance to apoptosis is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b0483ba6841122a031e009f0d25306
https://doi.org/10.1158/2159-8290.c.6549622.v1
https://doi.org/10.1158/2159-8290.c.6549622.v1
Autor:
Bruno Calabretta, Alexander Mazo, Christine M. Eischen, Paolo Fortina, Adam Ertel, Pierluigi Porcu, Neil Palmisiano, Eli Canaani, Alessandro Gardini, Marco Trizzino, Alexis Grande, Sandra Deliard, Elisa Barbieri, Valentina Minieri, Gaurav Kumar, Saul Kushinsky, Matthew V. Puccetti, David Deming, Marco De Dominici, Luca Pagliaroli, Svetlana Petruk, Patrizia Porazzi
Despite treatment with intensive chemotherapy, acute myelogenous leukemia (AML) remains an aggressive malignancy with a dismal outcome in most patients. We found that AML cells exhibit an unusually rapid accumulation of the repressive histone mark H3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec590e126a2276bbb1c315321caff927
https://doi.org/10.1158/0008-5472.c.6513811.v1
https://doi.org/10.1158/0008-5472.c.6513811.v1
Autor:
Bruno Calabretta, Marja T. Nevalainen, Pierluigi Porcu, Luke F. Peterson, Alessandro Rambaldi, Orietta Spinelli, Samanta A. Mariani, Patrizia Porazzi, Marco De Dominici, Valentina Minieri
Primary human Ph+ ALL samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef6d62ceef6c04e37078b2c582e3932
https://doi.org/10.1158/0008-5472.22420215
https://doi.org/10.1158/0008-5472.22420215