Spotlight on Secondary Metabolites Produced by an Early-Flowering Apulian Artichoke Ecotype Sanitized from Virus Infection by Meristem-Tip-Culture and Thermotherapy

Autor: Roberta Spanò, Patrizia Gena, Vito Linsalata, Valeria Sini, Isabella D’Antuono, Angela Cardinali, Pietro Cotugno, Giuseppe Calamita, Tiziana Mascia

Publikováno v: Antioxidants, Vol 13, Iss 7, p 852 (2024)

Globe artichoke (Cynara cardunculus L. subsp. scolymus) is an important crop of the Mediterranean basin characterized by many properties, like hepatoprotective, anticarcinogenic, antioxidant, antibacterial, and beneficial to human health. The high bi

Externí odkaz: https://doaj.org/article/5b830c90572e4e0599c200f2fe67b2eb

Characterization of the Aquaporin-9 Inhibitor RG100204 In Vitro and in db/db Mice

Autor: Marilina Florio, Angelica Engfors, Patrizia Gena, Jessica Larsson, Alessandro Massaro, Stella Timpka, Martina Kvist Reimer, Per Kjellbom, Eric Beitz, Urban Johanson, Michael Rützler, Giuseppe Calamita

Publikováno v: Cells, Vol 11, Iss 19, p 3118 (2022)

Aquaporin-9 (AQP9) is a facilitator of glycerol and other small neutral solute transmembrane diffusion. Identification of specific inhibitors for aquaporin family proteins has been difficult, due to high sequence similarity between the 13 human isofo

Externí odkaz: https://doaj.org/article/661d4ca979a64e47b3f85e59af6b2c7f

Corrigendum: Aquaporin-9 Contributes to the Maturation Process and Inflammatory Cytokine Secretion of Murine Dendritic Cells

Autor: Stefania De Santis, Grazia Serino, Maria R. Fiorentino, Vanessa Galleggiante, Patrizia Gena, Giulio Verna, Marina Liso, Monica Massaro, Jinggang Lan, Jacopo Troisi, Ilaria Cataldo, Alessia Bertamino, Aldo Pinto, Pietro Campiglia, Angelo Santino, Gianluigi Giannelli, Alessio Fasano, Giuseppe Calamita, Marcello Chieppa

Publikováno v: Frontiers in Immunology, Vol 10 (2019)

Externí odkaz: https://doaj.org/article/54d051402b7a452882f1fb00e77564d1

In Vitro and In Vivo Nutraceutical Characterization of Two Chickpea Accessions: Differential Effects on Hepatic Lipid Over-Accumulation

Autor: Mariangela Centrone, Patrizia Gena, Marianna Ranieri, Annarita Di Mise, Mariagrazia D’Agostino, Maria Mastrodonato, Maria Venneri, Davide De Angelis, Stefano Pavan, Antonella Pasqualone, Carmine Summo, Valentina Fanelli, Giovanna Valenti, Giuseppe Calamita, Grazia Tamma

Publikováno v: Antioxidants, Vol 9, Iss 3, p 268 (2020)

Dietary habits are crucially important to prevent the development of lifestyle-associated diseases. Diets supplemented with chickpeas have numerous benefits and are known to improve body fat composition. The present study was undertaken to characteri

Externí odkaz: https://doaj.org/article/05cc45aed6454f84a1ea372c42595b9d

Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors

Autor: Tania Singh, Yonathan Sonntag, Michal K. Oklinski, Anna Maggio, Isabella Artner, Per Kjellbom, John Nieland, Michael Rützler, Søren Nielsen, Urban Johanson, Giuseppe Calamita, Patrizia Gena

Publikováno v: Sonntag, Y, Gena, P, Maggio, A, Singh, T, Artner, I, Oklinski, M K, Johanson, U, Kjellbom, P, Nieland, J D, Nielsen, S, Calamita, G & Rützler, M 2019, ' Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors ', The Journal of Biological Chemistry, vol. 294, no. 18, pp. 7377-7387 . https://doi.org/10.1074/jbc.RA118.006083
J Biol Chem

The aquaglyceroporins are a subfamily of aquaporins that conduct both water and glycerol. Aquaporin-3 (AQP3) has an important physiological function in renal water reabsorption, and AQP3- mediated hydrogen peroxide (H 2O 2) permeability can enhance c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11ad23a6321dcbbb8b1bc917895b869
https://doi.org/10.1074/jbc.ra118.006083