Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Patrizia, Diana"'
Autor:
Antonino Glaviano, Aaron S. C. Foo, Hiu Y. Lam, Kenneth C. H. Yap, William Jacot, Robert H. Jones, Huiyan Eng, Madhumathy G. Nair, Pooyan Makvandi, Birgit Geoerger, Matthew H. Kulke, Richard D. Baird, Jyothi S. Prabhu, Daniela Carbone, Camilla Pecoraro, Daniel B. L. Teh, Gautam Sethi, Vincenzo Cavalieri, Kevin H. Lin, Nathalie R. Javidi-Sharifi, Eneda Toska, Matthew S. Davids, Jennifer R. Brown, Patrizia Diana, Justin Stebbing, David A. Fruman, Alan P. Kumar
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-37 (2023)
Abstract The PI3K/AKT/mTOR (PAM) signaling pathway is a highly conserved signal transduction network in eukaryotic cells that promotes cell survival, cell growth, and cell cycle progression. Growth factor signalling to transcription factors in the PA
Externí odkaz:
https://doaj.org/article/9b643e4724194798a585634205af8fef
Autor:
Mark F. Santos, Germana Rappa, Jana Karbanová, Patrizia Diana, Girolamo Cirrincione, Daniela Carbone, David Manna, Feryal Aalam, David Wang, Cheryl Vanier, Denis Corbeil, Aurelio Lorico
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract The mechanism of human immunodeficiency virus 1 (HIV-1) nuclear entry, required for productive infection, is not fully understood. Here, we report that in HeLa cells and activated CD4+ T cells infected with HIV-1 pseudotyped with VSV-G and n
Externí odkaz:
https://doaj.org/article/655f2362a6824c5ab6eb44b512bed94c
Autor:
Daniela Carbone, Camilla Pecoraro, Fabio Scianò, Valentina Catania, Domenico Schillaci, Barbara Manachini, Stella Cascioferro, Patrizia Diana, Barbara Parrino
Publikováno v:
Marine Drugs, Vol 22, Iss 3, p 133 (2024)
Biofilm-associated infections pose significant challenges in healthcare settings due to their resistance to conventional antimicrobial therapies. In the last decade, the marine environment has been a precious source of bioactive molecules, including
Externí odkaz:
https://doaj.org/article/aace559fdbc9482aa8bc74a8f263d6a3
Autor:
I Gede Putu Supadmanaba, Giulia Mantini, Ornella Randazzo, Mjriam Capula, Ittai B. Muller, Stella Cascioferro, Patrizia Diana, Godefridus J. Peters, Elisa Giovannetti
Publikováno v:
Epigenetics, Vol 17, Iss 4, Pp 381-404 (2022)
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers because of diagnosis at late stage and inherent/acquired chemoresistance. Recent advances in genomic profiling and biology of this disease have not yet been translated to a rel
Externí odkaz:
https://doaj.org/article/95e67049e83d471fb22f4dea5968ac00
Autor:
Camilla Pecoraro, Francesca Terrana, Giovanna Panzeca, Barbara Parrino, Stella Cascioferro, Patrizia Diana, Elisa Giovannetti, Daniela Carbone
Publikováno v:
Molecules, Vol 28, Iss 18, p 6450 (2023)
The marine environment is an excellent source of molecules that have a wide structural diversity and a variety of biological activities. Many marine natural products (MNPs) have been established as leads for anticancer drug discovery. Most of these c
Externí odkaz:
https://doaj.org/article/35f42eb732474d3ca1a712d0e6773846
Autor:
Ignazio Restivo, Manuela Giovanna Basilicata, Ilenia Concetta Giardina, Alessandro Massaro, Giacomo Pepe, Emanuela Salviati, Camilla Pecoraro, Daniela Carbone, Stella Cascioferro, Barbara Parrino, Patrizia Diana, Carmine Ostacolo, Pietro Campiglia, Alessandro Attanzio, Antonella D’Anneo, Fanny Pojero, Mario Allegra, Luisa Tesoriere
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1621 (2023)
We here investigated the anti-inflammatory activity of a polymethoxylated flavone-containing fraction (PMFF) from Citrus sinensis and of a prenylflavonoid-containing one (PFF) from Humulus lupulus, either alone or in combination (MIX). To this end, a
Externí odkaz:
https://doaj.org/article/2fb4d66921f74d7b99926c6757681b73
Autor:
Daniela Carbone, Camilla Pecoraro, Giovanna Panzeca, Geng Xu, Margot S. F. Roeten, Stella Cascioferro, Elisa Giovannetti, Patrizia Diana, Barbara Parrino
Publikováno v:
Marine Drugs, Vol 21, Iss 7, p 412 (2023)
A new series of nortopsentin analogs, in which the central imidazole ring of the natural lead was replaced by a 1,3,4-oxadiazole or 1,3,4-thiadiazole moiety, was efficiently synthesized. The antiproliferative activity of all synthesized derivatives w
Externí odkaz:
https://doaj.org/article/b9842e404649486cbce5b16e2eeda733
Autor:
Daniela Carbone, Michele De Franco, Camilla Pecoraro, Davide Bassani, Matteo Pavan, Stella Cascioferro, Barbara Parrino, Girolamo Cirrincione, Stefano Dall’Acqua, Stefania Sut, Stefano Moro, Valentina Gandin, Patrizia Diana
Publikováno v:
Marine Drugs, Vol 21, Iss 5, p 288 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is one of the main aggressive types of cancer, characterized by late prognosis and drug resistance. Among the main factors sustaining PDAC progression, the alteration of cell metabolism has emerged to have a ke
Externí odkaz:
https://doaj.org/article/459f75d902884714a80923606fbf5a77
Autor:
Daniele Aiello, Hendrik Jonas, Anna Carbone, Daniela Carbone, Camilla Pecoraro, Luisa Tesoriere, Jens Köhler, Bernhard Wünsch, Patrizia Diana
Publikováno v:
Molecules, Vol 27, Iss 21, p 7423 (2022)
Natural products are an excellent source of inspiration for the development of new drugs. Among them, betalains have been extensively studied for their antioxidant properties and potential application as natural food dyes. Herein, we describe the sev
Externí odkaz:
https://doaj.org/article/26c961918f1c47e58a1cb516957dfdd0
Autor:
Mark F. Santos, Germana Rappa, Jana Karbanová, Simona Fontana, Maria Antonietta Di Bella, Marshall R. Pope, Barbara Parrino, Stella Maria Cascioferro, Giulio Vistoli, Patrizia Diana, Girolamo Cirrincione, Goffredo O. Arena, Gyunghwi Woo, Kevin Huang, Tony Huynh, Marta Moschetti, Riccardo Alessandro, Denis Corbeil, Aurelio Lorico
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 10, Pp n/a-n/a (2021)
ABSTRACT Extracellular vesicles (EVs) are mediators of intercellular communication under both healthy and pathological conditions, including the induction of pro‐metastatic traits, but it is not yet known how and where functional cargoes of EVs are
Externí odkaz:
https://doaj.org/article/861bc07de0194278a252706feac6faa3