Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Patrik Scholz"'
Autor:
Manuela Gries, Cornelia M. Keck, Steven Schulte, Monika Martin, Pascal L Stahr, Karl-Herbert Schäfer, Anne Christmann, Sven Ingebrandt, Patrik Scholz, Jessica Ka-Yan Law, Rainer Lilischkis
Publikováno v:
Biological Chemistry. 403:103-122
Motoric disturbances in Parkinson’s disease (PD) derive from the loss of dopaminergic neurons in the substantia nigra. Intestinal dysfunctions often appear long before manifestation of neuronal symptoms, suggesting a strong correlation between gut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cacfc674c80ef3658a7dcf3332c10a98
https://doi.org/10.1515/hsz-2021-0259
https://doi.org/10.1515/hsz-2021-0259
Autor:
Anne, Christmann, Manuela, Gries, Patrik, Scholz, Pascal L, Stahr, Jessica Ka Yan, Law, Steven, Schulte, Monika, Martin, Rainer, Lilischkis, Sven, Ingebrandt, Cornelia M, Keck, Karl-Herbert, Schäfer
Publikováno v:
Biological chemistryReferences. 403(1)
Motoric disturbances in Parkinson's disease (PD) derive from the loss of dopaminergic neurons in the substantia nigra. Intestinal dysfunctions often appear long before manifestation of neuronal symptoms, suggesting a strong correlation between gut an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f62e77b5c51361e7907a1f3657076d65
https://pubmed.ncbi.nlm.nih.gov/34582634
https://pubmed.ncbi.nlm.nih.gov/34582634
Autor:
Patrik Scholz, Natalie Geisel, Pascal-L. Stahr, Henriette Dietrich, Cornelia M. Keck, Olga Pelikh, Jing Huang, Martin Gerst
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 128
Nanocrystals are composed of 100% active and possess an increased aqueous solubility and dissolution velocity when compared to larger sized materials. Nanocrystals can be used to improve the bioavailability of poorly soluble actives not only for oral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f552d61914f3d1596c276772c5fd3a
https://pubmed.ncbi.nlm.nih.gov/29680482
https://pubmed.ncbi.nlm.nih.gov/29680482
Autor:
Patrik Scholz, Cornelia M. Keck
Publikováno v:
Current Pharmaceutical Design. 21:4217-4228
Many new developed drug actives are poorly soluble, therefore the need to increase the solubility of these actives arises. Nanosuspensions are fast and easy to produce, enhance the bioavailability of poorly soluble drugs and feature many beneficial c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379d743666e9c799b3935aa017c87e79
https://doi.org/10.2174/1381612821666150901100417
https://doi.org/10.2174/1381612821666150901100417
Publikováno v:
Chemico-biological interactions. 280
The skin is exposed to many stress factors which, in turn, can promote a shift of the antioxidant (AO) network towards the prooxidative side, supporting the development of various skin disorders. A balanced diet, in combination with a healthy lifesty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d70e9bdb918971ef50bbd7a17cd7889
https://pubmed.ncbi.nlm.nih.gov/29203372
https://pubmed.ncbi.nlm.nih.gov/29203372
Publikováno v:
International Journal of Pharmaceutics. 465:388-395
The ARTcrystal process is a new approach for the production of drug nanocrystals. It is a combination of a special pre-treatment step with subsequent high pressure homogenization (HPH) at low pressures. In the pre-treatment step the particle size is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e8b5d174382f6ba9ad9766f19422d9
https://doi.org/10.1016/j.ijpharm.2014.02.026
https://doi.org/10.1016/j.ijpharm.2014.02.026
Autor:
Cornelia M. Keck, Patrik Scholz
Publikováno v:
International journal of pharmaceutics. 482(1-2)
Nanoemulsions were produced by high speed stirring using an ART MICCRA D27 rotor-stator system. Nanoemulsions with a droplet size of 135 nm and a narrow size distribution were obtained. The emulsions are physically stable for at least three months. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29dc3852971c2e3e7d788a7f769f94df
https://pubmed.ncbi.nlm.nih.gov/25532442
https://pubmed.ncbi.nlm.nih.gov/25532442
Autor:
Cornelia M. Keck, Patrik Scholz
Publikováno v:
International journal of pharmaceutics. 482(1-2)
ARTcrystal(®)-technology is a novel technique for a more efficient production of nanocrystals. It consists of a high speed stirring (HSS) step as pre-milling and subsequent high pressure homogenization (HPH) at reduced pressure and cycle numbers. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3b89d561c4daf12721ce6d9f2ea7bc
https://pubmed.ncbi.nlm.nih.gov/25448550
https://pubmed.ncbi.nlm.nih.gov/25448550