Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Patrik Oleksak"'
Autor:
Champa Keeya Tudu, Tusheema Dutta, Mimosa Ghorai, Protha Biswas, Dipu Samanta, Patrik Oleksak, Niraj Kumar Jha, Manoj Kumar, Radha, Jarosław Proćków, José M. Pérez de laLastra, Abhijit Dey
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/07f1f0ad7a6d48c59bdf9958a1157fae
Autor:
Jiri Patocka, Wenda Wu, Patrik Oleksak, Romana Jelinkova, Eugenie Nepovimova, Lenka Spicanova, Pavlina Springerova, Suliman Alomar, Miao Long, Kamil Kuca
Publikováno v:
Heliyon, Vol 10, Iss 8, Pp e28795- (2024)
Fentanyl is a synthetic μ-opioid receptor agonist approved to treat severe to moderate pain with faster onset of action and about 100 times more potent than morphine. Over last two decades, abuse of fentanyl and its derivatives has an increased tren
Externí odkaz:
https://doaj.org/article/cf3866a19cce4d84b3ee9175af12f37e
Autor:
Zofia Chrienova, Eugenie Nepovimova, Rudolf Andrys, Rafael Dolezal, Jana Janockova, Lubica Muckova, Lenka Fabova, Ondrej Soukup, Patrik Oleksak, Martin Valis, Jan Korabecny, José Marco-Contelles, Kamil Kuca
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2605-2620 (2022)
Twenty-four novel compounds bearing tetrahydroacridine and N-propargyl moieties have been designed, synthesised, and evaluated in vitro for their anti-cholinesterase and anti-monoamine oxidase activities. Propargyltacrine 23 (IC50 = 21 nM) was the mo
Externí odkaz:
https://doaj.org/article/1b4b604d4ed2463eadfec515d42a5564
Autor:
Zofia Chrienova, David Rysanek, Patrik Oleksak, Dorota Stary, Marek Bajda, Milan Reinis, Romana Mikyskova, Ondrej Novotny, Rudolf Andrys, Adam Skarka, Pavla Vasicova, Josef Novak, Martin Valis, Kamil Kuca, Zdenek Hodny, Eugenie Nepovimova
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
To date, the most studied drug in anti-aging research is the mTOR inhibitor – rapamycin. Despite its almost perfect anti-aging profile, rapamycin exerts one significant limitation – inappropriate physicochemical properties. Therefore, we have dec
Externí odkaz:
https://doaj.org/article/2138141c119d4080852852773bb5684e
Autor:
Champa Keeya Tudu, Tusheema Dutta, Mimosa Ghorai, Protha Biswas, Dipu Samanta, Patrik Oleksak, Niraj Kumar Jha, Manoj Kumar, Radha, Jarosław Proćków, José M. Pérez de la Lastra, Abhijit Dey
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Allium sativum L. (Garlic) is a fragrant herb and tuber-derived spice that is one of the most sought-after botanicals, used as a culinary and ethnomedicine for a variety of diseases around the world. An array of pharmacological attributes such as ant
Externí odkaz:
https://doaj.org/article/dd2c48d59d7a43bb9f4d5dc33b400d5f
Autor:
Swati Halder, Uttpal Anand, Samapika Nandy, Patrik Oleksak, Safaa Qusti, Eida M. Alshammari, Gaber El-Saber Batiha, Eapen P. Koshy, Abhijit Dey
Publikováno v:
Saudi Pharmaceutical Journal, Vol 29, Iss 8, Pp 879-907 (2021)
Memory, one of the most vital aspects of the human brain, is necessary for the effective survival of an individual. ‘Memory’ can be defined in various ways but in an overall view, memory is the retention of the information that the brain grasps.
Externí odkaz:
https://doaj.org/article/70b55c24b88241a482c127b0d44bc747
Autor:
Patrik Oleksak, Miroslav Psotka, Marketa Vancurova, Olena Sapega, Jana Bieblova, Milan Reinis, David Rysanek, Romana Mikyskova, Katarina Chalupova, David Malinak, Jana Svobodova, Rudolf Andrys, Helena Rehulkova, Vojtech Skopek, Pham Ngoc Lam, Jiri Bartek, Zdenek Hodny, Kamil Musilek
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 410-424 (2021)
Twelve novel analogs of STAT3 inhibitor BP-1-102 were designed and synthesised with the aim to modify hydrophobic fragments of the molecules that are important for interaction with the STAT3 SH2 domain. The cytotoxic activity of the reference and nov
Externí odkaz:
https://doaj.org/article/cfac0c0e4320428ab38cfae14e7c28f8
Autor:
Le Yang, Junbang Wang, Yongsheng Yang, Sha Li, Tongxin Wang, Patrik Oleksak, Zofia Chrienova, Qinghua Wu, Eugenie Nepovimova, Xiujuan Zhang, Kamil Kuca
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 234, Iss , Pp 113403- (2022)
To clarify the global status and research hotspots of heavy metal pollution phytoremediation, we used Web of Science, Cite Space software, and VOS viewer to analyse 1123 publications from the period of 2000–2020. Literature categories, research hot
Externí odkaz:
https://doaj.org/article/ac23dd1f803641fd86aa7616a930ff6a
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Antimicrobial peptides are an important component of many organisms’ innate immune system, with a good inhibitory or killing effect against the invading pathogens. As a type of biological polypeptide with natural immune activities, antimicrobial pe
Externí odkaz:
https://doaj.org/article/96f0cee09f4e4910934e089c6d201526
Autor:
Harsh Kumar, Kanchan Bhardwaj, Natália Cruz-Martins, Eugenie Nepovimova, Patrik Oleksak, Daljeet Singh Dhanjal, Sonali Bhardwaj, Reena Singh, Chirag Chopra, Rachna Verma, Prem Parkash Chauhan, Dinesh Kumar, Kamil Kuča
Publikováno v:
Molecules, Vol 26, Iss 11, p 3447 (2021)
The ingestion of contaminated water and food is known to cause food illness. Moreover, on assessing the patients suffering from foodborne disease has revealed the role of microbes in such diseases. Concerning which different methods have been develop
Externí odkaz:
https://doaj.org/article/e87d80f693394bd6bb1d187710c3a5fa