Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Patrik Edén"'
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Sentinel lymph node biopsy (SLNB) is standard staging procedure for nodal status in breast cancer, but lacks therapeutic benefit for patients with benign sentinel nodes. For patients with positive sentinel nodes, individualized su
Externí odkaz:
https://doaj.org/article/d11fbeb4f894420bb0db09bfdbeb3e1c
Autor:
Ulrika Axelsson, Lisa Rydén, Per Johnsson, Patrik Edén, Johanna Månsson, Ingalill Rahm Hallberg, Carl A. K. Borrebaeck
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-7 (2018)
Abstract Background Individual patients differ in their psychological response when receiving a cancer diagnosis, in this case breast cancer. Given the same disease burden, some patients master the situation well, while others experience a great deal
Externí odkaz:
https://doaj.org/article/181f1a28116044fba640fa2cc56a357c
Autor:
Martin Sjöström, Johan Staaf, Patrik Edén, Fredrik Wärnberg, Jonas Bergh, Per Malmström, Mårten Fernö, Emma Niméus, Irma Fredriksson
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-13 (2018)
Abstract Background Adjuvant radiotherapy is the standard of care after breast-conserving surgery for primary breast cancer, despite a majority of patients being over- or under-treated. In contrast to adjuvant endocrine therapy and chemotherapy, no d
Externí odkaz:
https://doaj.org/article/ff2a63d745da4d41932390437e13265a
Autor:
Cristina Pina, José Teles, Cristina Fugazza, Gillian May, Dapeng Wang, Yanping Guo, Shamit Soneji, John Brown, Patrik Edén, Mattias Ohlsson, Carsten Peterson, Tariq Enver
Publikováno v:
Cell Reports, Vol 11, Iss 10, Pp 1503-1510 (2015)
We explore cell heterogeneity during spontaneous and transcription-factor-driven commitment for network inference in hematopoiesis. Since individual genes display discrete OFF states or a distribution of ON levels, we compute and combine pairwise gen
Externí odkaz:
https://doaj.org/article/0db5ae2c5e1549f380a996b2f9c21770
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137597 (2015)
We investigate a new method to place patients into risk groups in censored survival data. Properties such as median survival time, and end survival rate, are implicitly improved by optimizing the area under the survival curve. Artificial neural netwo
Externí odkaz:
https://doaj.org/article/b59ad98dbb064ab09082cd5dfe308109
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 8, p e1003197 (2013)
Molecular mechanisms employed by individual multipotent cells at the point of lineage commitment remain largely uncharacterized. Current paradigms span from instructive to noise-driven mechanisms. Of considerable interest is also whether commitment i
Externí odkaz:
https://doaj.org/article/b294fb30456d41d09799d87937850e1b
Autor:
Mårten Fernö, Åke Borg, Jorma Isola, Per Malmström, Carsten Peterson, Patrik Edén, Cecilia Hegardt, Mervi Laakso, Lao H. Saal, Pär-Ola Bendahl, Sofia K. Gruvberger-Saal
Purpose: Endocrine therapies, such as tamoxifen, are commonly given to most patients with estrogen receptor (ERα)–positive breast carcinoma but are not indicated for persons with ERα-negative cancer. The factors responsible for response to tamoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da10c0df3e0eaa0907b1583792ff058
https://doi.org/10.1158/1078-0432.c.6518757.v1
https://doi.org/10.1158/1078-0432.c.6518757.v1
Autor:
Paul S. Meltzer, Carsten Peterson, Mårten Fernö, Åke Borg, Gunilla Chebil, Bo Baldetorp, Markus Ringnér, Patrik Edén, Sofia K. Gruvberger-Saal
The prognostic and treatment-predictive markers currently in use for breast cancer are commonly based on the protein levels of individual genes (e.g., steroid receptors) or aspects of the tumor phenotype, such as histological grade and percentage of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371b1ab64ae431bb681b0e5f7b8347a3
https://doi.org/10.1158/1535-7163.c.6532193
https://doi.org/10.1158/1535-7163.c.6532193
Autor:
Paul S. Meltzer, Carsten Peterson, Mårten Fernö, Åke Borg, Gunilla Chebil, Bo Baldetorp, Markus Ringnér, Patrik Edén, Sofia K. Gruvberger-Saal
Analysis + 1 Figure and 3 Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474079d6fcf3002d1f736cb77afeded8
https://doi.org/10.1158/1535-7163.22486022
https://doi.org/10.1158/1535-7163.22486022
Autor:
Mårten Fernö, Åke Borg, Jorma Isola, Per Malmström, Carsten Peterson, Patrik Edén, Cecilia Hegardt, Mervi Laakso, Lao H. Saal, Pär-Ola Bendahl, Sofia K. Gruvberger-Saal
Supplementary Materials and Methods, along with Supplementary Figure S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011ae9bf6254e59d7711cccdfa686434
https://doi.org/10.1158/1078-0432.22441866.v1
https://doi.org/10.1158/1078-0432.22441866.v1