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pro vyhledávání: '"Patricke E. Benedict"'
Autor:
Mita Ghosh, William O. Dobbins, Patricke E. Benedict, Phyllissa Schmiedlin-Ren, Paul B. Watkins, Joseph C. Kolars
Publikováno v:
Biochemical Pharmacology. 46:905-918
Enzymes within the CYP3A subfamily are major Phase I drug-metabolizing enzymes present in hepatocytes and small bowel enterocytes. These enzymes are highly inducible in the liver by many structurally diverse compounds, including a number of commonly