Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Patrick Y. Kim"'
Autor:
Emiko Kranz, Charles J. Kuhlmann, Joshua Chan, Patrick Y. Kim, Irvin S. Y. Chen, Masakazu Kamata
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chimeric-antigen receptor (CAR) T-cell immunotherapy employs autologous-T cells modified with an antigen-specific CAR. Current CAR-T manufacturing processes tend to yield products dominated by effector T cells and relatively small proportions of long
Externí odkaz:
https://doaj.org/article/a1656d681fe741bb9e4556569cdda034
Autor:
Janith A. Seneviratne, Daniel R. Carter, Rituparna Mittra, Andrew Gifford, Patrick Y. Kim, Jie‐Si Luo, Chelsea Mayoh, Alice Salib, Aldwin S. Rahmanto, Jayne Murray, Ngan C. Cheng, Zsuzsanna Nagy, Qian Wang, Ane Kleynhans, Owen Tan, Selina K. Sutton, Chengyuan Xue, Sylvia A. Chung, Yizhuo Zhang, Chengtao Sun, Li Zhang, Michelle Haber, Murray D. Norris, Jamie I. Fletcher, Tao Liu, Pierre J. Dilda, Philip J. Hogg, Belamy B. Cheung, Glenn M. Marshall
Publikováno v:
International Journal of Cancer. 152:1399-1413
The mitochondrion is a gatekeeper of apoptotic processes, and mediates drug resistance to several chemotherapy agents used to treat cancer. Neuroblastoma is a common solid cancer in young children with poor clinical outcomes following conventional ch
Autor:
Frank K. Liou, Patrick Y. Kim, S. Paran Yap, Abdullah Khan, Sandra Taylor, Rex Pillai, Eric King, Amol Shah, R. Torrance Andrews, Catherine T. Vu, Roger E. Goldman
Publikováno v:
Cardiovascular and interventional radiology, vol 46, iss 1
Introduction Clinical outcomes of implantable port catheters (IPCs) placed via alternative veins such as the external jugular and cervical collaterals have not been well established. This investigation evaluates the short- and long-term outcomes of I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922d06a349e66ecbad7c78844d1095ca
https://escholarship.org/uc/item/01w474pm
https://escholarship.org/uc/item/01w474pm
Autor:
Owen Tan, Sonya M. Diakiw, Patrick Y. Kim, Janith A. Seneviratne, Chelsea Mayoh, Olle Sangfelt, Naresh Kumar, Daniel R. Carter, Rituparna Mittra, Ane Kleynhans, Michelle Haber, Belamy B. Cheung, Zsuzsanna Nagy, Jessica K Holien, Murray D. Norris, Aldwin Suryano, Iris Poh Ling Wong, Bing Liu, Olivia C. Ciampa, Hassina Massudi, Mukesh Raipuria, Andrew Gong, Tao Liu, Michael W. Parker, Shizhen Zhu, Greg M. Arndt, Glenn M. Marshall, Satyanarayana Gadde
Publikováno v:
Oncogene
Histone deacetylase (HDAC) inhibitors are effective in MYCN-driven cancers, because of a unique need for HDAC recruitment by the MYCN oncogenic signal. However, HDAC inhibitors are much more effective in combination with other anti-cancer agents. To
Autor:
Frank K, Liou, Patrick Y, Kim, S Paran, Yap, Abdullah, Khan, Sandra, Taylor, Rex, Pillai, Eric, King, Amol, Shah, R Torrance, Andrews, Catherine T, Vu, Roger E, Goldman
Publikováno v:
Cardiovascular and interventional radiology. 46(1)
Clinical outcomes of implantable port catheters (IPCs) placed via alternative veins such as the external jugular and cervical collaterals have not been well established. This investigation evaluates the short- and long-term outcomes of IPCs inserted
Autor:
Gene-Errol E Ringpis, Saki Shimizu, Hubert Arokium, Joanna Camba-Colón, Maria V Carroll, Ruth Cortado, Yiming Xie, Patrick Y Kim, Anna Sahakyan, Emily L Lowe, Munetoshi Narukawa, Fadi N Kandarian, Bryan P Burke, Geoff P Symonds, Dong Sung An, Irvin S Y Chen, Masakazu Kamata
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53492 (2012)
Down-regulation of the HIV-1 coreceptor CCR5 holds significant potential for long-term protection against HIV-1 in patients. Using the humanized bone marrow/liver/thymus (hu-BLT) mouse model which allows investigation of human hematopoietic stem/prog
Externí odkaz:
https://doaj.org/article/2b0ee1ff496b470290d5a8ee5f6b119e
Autor:
Jennifer Lam, Ruth Cortado, Yiming Xie, Angela P. Presson, Yujin Jung, Masakazu Kamata, Hubert Arokium, Irvin S. Y. Chen, Wannisa Khamaikawin, Patrick Y. Kim, Dong Sung An, Sanggu Kim, Jing Wen, Saki Shimizu
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 9, Iss, Pp 23-32 (2018)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Investigations of anti-HIV-1 human hematopoietic stem/progenitor cell (HSPC)-based gene therapy have been performed by HIV-1 challenge after the engraftment of gene-modified HSPCs in humanized mouse models. However, the clinical application of gene t
Autor:
Owen Tan, Belamy B. Cheung, Toby Trahair, Bing Liu, Murray D. Norris, Michelle Haber, Glenn M. Marshall, Tao Liu, Patrick Y. Kim
Publikováno v:
Cancer Letters. 374:315-323
Tripartite Motif-containing protein 16 (TRIM16) is a member of a large family of tripartite motif (TRIM) proteins, that has been implicated in the pathogenesis of multiple cancers. However, the mechanism by which TRIM16 acts as a tumour suppressor is
Autor:
Patrick Y. Kim, Otto O. Yang, Emiko Kranz, Masakazu Kamata, Sean M. O'connor, Gene-Errol Ringpis, Hwee L. Ng, Irvin S. Y. Chen, Joshua Chan
Publikováno v:
Biochemical and Biophysical Research Communications. 463:216-221
Chimeric antigen receptors (CARs) are artificially engineered receptors that confer a desired specificity to immune effector T cells. As an HIV-1-specific CAR, CD4ζ CAR has been extensively tested in vitro as well as in clinical trials. T cells modi
Autor:
Glenn M. Marshall, Toby Trahair, Owen Tan, Eric O. Sekerye, Sonya M. Diakiw, Valerie C. Wasinger, Patrick Y. Kim, Tao Liu, Lou Chesler, Maria Kavallaris, Alla Dolnikov, Murray D. Norris, Michelle Haber, Belamy B. Cheung, Daniel R. Carter, Nai Kong Cheung
Publikováno v:
Journal of Proteomics. 96:1-12
The majority of patients diagnosed with neuroblastoma present with aggressive disease. Improved detection of neuroblastoma cancer cells following initial therapy may help in stratifying patient outcome and monitoring for relapse. To identify potentia